Results 11 to 20 of about 5,306 (202)

In Vitro and In Vivo Evaluation of Oral Controlled Release Formulation of BCS Class I Drug Using Polymer Matrix System

open access: yesPharmaceuticals, 2021
Diltiazem hydrochloride is a calcium channel blocker, which belongs to the family of benzothiazepines. It is commonly used to treat hypertension and atrial fibrillation. Even though the drug has high solubility, its high permeability and rapid metabolism
Mosab Arafat   +5 more
doaj   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale. [PDF]

open access: yesGeriatr Gerontol Int
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Mogi M   +4 more
europepmc   +2 more sources

Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film

open access: yesIndonesian Journal of Pharmacy, 2021
Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti   +2 more
doaj   +1 more source

Thermodynamics of clay–drug complex dispersions: Isothermal titration calorimetry and high-performance liquid chromatography

open access: yesJournal of Pharmaceutical Analysis, 2020
An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several characterisation techniques as well as isothermal calorimetry were utilized in investigating the ...
Ana-Maria Totea   +7 more
doaj   +1 more source

Highly stretchable gelatin‐polyacrylamide hydrogel for potential transdermal drug release

open access: yesNano Select, 2021
Stretchable hydrogels have been used for a number of biomedical applications. This research focused on the study of a highly stretchable and tough hydrogel made of gelatin and polyacrylamide towards transdermal drug delivery applications.
Zhen Qiao   +6 more
doaj   +1 more source

A novel stability-indicating method for known and unknown impurities profiling for diltiazem hydrochloride pharmaceutical dosage form (tablets)

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background A novel gradient, high-sensitive and specific stability-indicating reverse-phase HPLC method was developed and validated for quantitative purpose of known, unknown and degradant impurities profiling for diltiazem hydrochloride tablets.
Nitin Mahajan   +2 more
doaj   +1 more source

Echocardiography used for treatment in heart failure accompanied by thyroid storm: Case report and literature review. [PDF]

open access: yesClin Case Rep
Key Clinical Message This case highlights the importance of carefully weighing the benefits and risks of beta‐adrenergic blockade therapy based on symptoms, echocardiography, and BNP values in thyroid storm patients. Abstract Thyroid storm is a rare but life‐threatening condition in thyrotoxic patients.
Wang S, Zhao Y, Yang Y, Pan Y, Wang K.
europepmc   +2 more sources

Wound, pressure ulcer, and burn guidelines (2023)-4: Guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers, third edition. [PDF]

open access: yesJ Dermatol
The Journal of Dermatology, Volume 52, Issue 6, Page e430-e480, June 2025.
Asano Y   +27 more
europepmc   +2 more sources

An Expired Non-Toxic Diltiazem Hydrochloride as Corrosion Inhibitor for Cu in Nitric Acid Medium

open access: yesInternational Journal of Electrochemical Science, 2017
The corrosion inhibition of Cu in 1 M HNO3 solution by expired Diltiazem Hydrochloride (HD) has been tested by Tafel polarization, electrical frequency modulation, electrical impedance spectroscopy, and mass loss method. The Diltiazem Hydrochloride gives
A.S. Fouda   +3 more
doaj   +1 more source

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