Results 11 to 20 of about 5,257 (204)
Journal of Advanced Pharmaceutical Technology & Research, 2013 The aim of the present study was to develop controlled-release pellets of diltiazem HCl with ethyl cellulose and hydroxylpropyl methylcellulose phthalate as the release rate retarding polymers by fluid bed coating technique.
Mikkilineni Bhanu Prasad +4 more
doaj +2 more sources
Pharmaceuticals, 2021 Diltiazem hydrochloride is a calcium channel blocker, which belongs to the family of benzothiazepines. It is commonly used to treat hypertension and atrial fibrillation. Even though the drug has high solubility, its high permeability and rapid metabolism
Mosab Arafat +5 more
doaj +1 more source
Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7-Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues. [PDF]
Drug Dev ResABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Chenu E +7 more
europepmc +2 more sources
Indonesian Journal of Pharmacy, 2021 Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti +2 more
doaj +1 more source
Journal of Pharmaceutical Analysis, 2020 An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several characterisation techniques as well as isothermal calorimetry were utilized in investigating the ...
Ana-Maria Totea +7 more
doaj +1 more source
Highly stretchable gelatin‐polyacrylamide hydrogel for potential transdermal drug release
Nano Select, 2021 Stretchable hydrogels have been used for a number of biomedical applications. This research focused on the study of a highly stretchable and tough hydrogel made of gelatin and polyacrylamide towards transdermal drug delivery applications.
Zhen Qiao +6 more
doaj +1 more source
Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale. [PDF]
Geriatr Gerontol IntABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Mogi M +4 more
europepmc +2 more sources
Future Journal of Pharmaceutical Sciences, 2021 Background A novel gradient, high-sensitive and specific stability-indicating reverse-phase HPLC method was developed and validated for quantitative purpose of known, unknown and degradant impurities profiling for diltiazem hydrochloride tablets.
Nitin Mahajan +2 more
doaj +1 more source
An Expired Non-Toxic Diltiazem Hydrochloride as Corrosion Inhibitor for Cu in Nitric Acid Medium
International Journal of Electrochemical Science, 2017 The corrosion inhibition of Cu in 1 M HNO3 solution by expired Diltiazem Hydrochloride (HD) has been tested by Tafel polarization, electrical frequency modulation, electrical impedance spectroscopy, and mass loss method. The Diltiazem Hydrochloride gives
A.S. Fouda +3 more
doaj +1 more source
Experimental Approval of the Efficacy of the Combined Composition Rectal Cream New Test-samples in the Conditions of Acute Complicated Anal Fissure in Rats [PDF]
, 2019 Anal fissure (AF) is one of the most common anorectal problems. The severity of the disease, the chronicity of the pathological process and frequent complications lead to a sharp deterioration in the quality of life of patients. An important place in the
Stakhorska, M. (Marina) +1 more
core +3 more sources