A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
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Release Characteristics of Diltiazem Hydrochloride Wax-Matrix Granules – Thermal Sintering Effect
Journal of Applied Sciences and Environmental Management, 2011 The aim of this study was to investigate the release characteristics of matrix (non-disintegrating) granules consisting of diltiazem hydrochloride (model drug) and glyceryl behenate (a wax matrix forming polymer) for sustained release application using ...
MU Uhumwangho, RMKV Ramana
doaj +1 more source
Impacts of compound properties and sediment characteristics on the sorption behaviour of pharmaceuticals in aquatic systems [PDF]
, 2016 Sorption is a key factor in determining the persistence, attenuation and bioavailability of sediment-associated contaminants. However, our understanding of the sorption behaviour of pharmaceuticals in sediments is poor. In this study, we investigated the
Al-Khazrajy, Omar S A +1 more
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Química Nova, 2011 This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate buffer at pH 6.8 as the dissolution ...
Taciane Ferreira Mendonça +4 more
doaj +1 more source
Aptamer-based cocaine assay using a nanohybrid composed of ZnS/Ag2Se quantum dots, graphene oxide and gold nanoparticles as a fluorescent probe [PDF]
, 2020 Authors report on a new fluoro-graphene-plasmonic nanohybrid aptamer-based fluorescent nanoprobe for cocaine. To construct the nanoprobe, newly synthesized glutathione-capped ZnS/Ag 2Se quantum dots (QDs) were first conjugated to graphene oxide (GO) to ...
Abdolvand, Amin +4 more
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Development of a Halothane-Adrenaline Arrhythmia Model Using In Vivo Guinea Pigs
Journal of Pharmacological Sciences, 2004 In vivo antiarrhythmic effects of diltiazem hydrochloride and nifekalant hydrochloride, a pure class III antiarrhythmic drug (Vaughan Williams’ classification), on adrenaline induced ventricular arrhythmias were examined in halothane anesthetized guinea ...
Yoshiaki Noda, Keitaro Hashimoto
doaj +1 more source
Wound, pressure ulcer, and burn guidelines (2023)-4: Guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers, third edition. [PDF]
J DermatolThe Journal of Dermatology, Volume 52, Issue 6, Page e430-e480, June 2025.
Asano Y +27 more
europepmc +2 more sources
Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment [PDF]
, 2016 Approximately 1500 active pharmaceutical ingredients are currently in use; however, the environmental occurrence and impacts of only a small proportion of these have been investigated.
Agerstrand +37 more
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Vegetable proteins in microencapsulation: a review of recent interventions and their effectiveness [PDF]
, 2013 Proteins from vegetable seeds are interesting for research at present because they are an abundant alternative to animal-based sources of proteins and petroleum-derived polymers.
Alric, Isabelle +3 more
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A prospective randomized trial of fk506 versus cyclosporine after human pulmonary transplantation [PDF]
, 1994 We have conducted a unique prospective randomized study to compare the effect of PK506 and cyclosporine (CsA) as the principal immunosuppressive agents after pulmonary transplantation.
Armitage, JM +11 more
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