Results 61 to 70 of about 25,927,166 (251)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Transforming Construction Waste into High-Performance Alkali-Activated Paste with Microstructural and Predictive π Modelling Insights

open access: yesBuildings
The construction industry is among the most resource-intensive sectors, generating nearly 40% of global CO2 emissions and over two billion tonnes of construction and demolition waste (CDW) annually. This study investigates the sustainable reuse of CDW in
Israf Javed   +2 more
doaj   +1 more source

Scaling Turbulent Combustion Fields in Explosions

open access: yesApplied Sciences, 2020
We considered the topic of explosions from spherical high-explosive (HE) charges. We studied how the turbulent combustion fields scale. On the basis of theories of dimensional analysis by Bridgman and similarity theories of Sedov and Barenblatt, we found
Allen Kuhl, David Grote, John Bell
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Proppant Transportation in Cross Fractures: Some Findings and Suggestions for Field Engineering

open access: yesEnergies, 2020
The proppant transportation is a typical two-phase flow process in a complex cross fracture network during hydraulic fracturing. In this paper, the proppant transportation in cross fractures is investigated by the computational fluid dynamics (CFD ...
Yan Zhang   +3 more
doaj   +1 more source

Clustering, Classification, and Factor Analysis in High Dimensional Data Analysis [PDF]

open access: yes, 2016
Clustering, classification, and factor analysis are three popular data mining techniques. In this dissertation, we investigate these methods in high dimensional data analysis.
Wang, Yanhong
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Assessing theoretical flow velocity profile and resistance in gravel bed rivers by field measurements

open access: yesJournal of Agricultural Engineering, 2018
Previous studies showed that integrating a power velocity profile, deduced applying dimensional analysis and the incomplete self-similarity condition, the flow resistance equation for open channel flow can be obtained.
Vito Ferro, Paolo Porto
doaj   +1 more source

Innovative solutions for enhanced illicit drugs profiling using comprehensive two-dimensional gas chromatography and mass spectrometry technologies [PDF]

open access: yes, 2014
This project aimed to determine whether comprehensive two-dimensional gas chromatography is suitable for routine use in a forensic laboratory for profiling illicit substances.
Philip Marriot, Blagoj Mitrevski
core  

Dimensional response analysis of multistorey regular steel MRF subjected to pulselike earthquake ground motions [PDF]

open access: yes, 2010
An alternative and efficient procedure to estimate the maximum inelastic roof displacement and the maximum inelastic interstorey drift ratio along the height of regular multi-storey steel MRF subjected to pulse-like ground motions is proposed. The method
Karavasilis, Theodore L.   +11 more
core   +1 more source

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