Results 121 to 130 of about 8,443,569 (339)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Flow Analysis of Space Shuttle Feed Line 17-inch Disconnect Valve [PDF]

, 1988
A steady incompressible three-dimensional viscous flow analysis has been conducted for the Space Shuttle External Tank/Orbiter propellant feed line disconnect flapper valves with upstream elbows.
Kandula, Max, Pearce, Daniel
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Impact of Part Positioning along Chamber Z-Axis and Processing Parameters in Selective Laser Sintering on Polyamide Properties

Applied Sciences
Additive manufacturing procedures are being increasingly developed, from prototyping to finished functional products. However, their rapid development also brings along the testing of properties with different manufacturing parameters. In selective laser
Ana Pilipović, Petar Ilinčić, Mislav Tujmer, Maja Rujnić Havstad   +3 more
doaj   +1 more source

Dimensional Stability of a Preliminary Vinyl Polysiloxane Impression Material

Dentistry Journal, 2019
Oral rehabilitation success depends upon the accuracy and dimensional stability of the impressions. The purpose of this study is to evaluate the dimensional changes of a first impression type VPS (Vinyl Polysiloxane) (Imprint™ 4 Preliminary Penta ...
Francisco Martins, José Reis, Ignacio Barbero Navarro, Paulo Maurício   +3 more
doaj   +1 more source

New Insights on Wood Dimensional Stability Influenced by Secondary Metabolites: The Case of a Fast-Growing Tropical Species Bagassa guianensis Aubl.

PLoS ONE, 2016
Challenging evaluation of tropical forest biodiversity requires the reporting of taxonomic diversity but also the systematic characterization of wood properties in order to discover new promising species for timber industry.
J. Bossu, J. Beauchêne, Y. Estevez, C. Duplais, Bruno Clair   +4 more
semanticscholar   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Effect of Hygroscopic Wood Structure on Some Properties of Heat Treated Products Formed with the Thermowood Method

BioResources
Changes were determined for the values ​​of physical and mechanical properties resulting from hygroscopicity in some wood species after heat treatment (HT), and to reveal statistically the relationships between the properties.
Ayhan Aytin
doaj