Results 71 to 80 of about 4,992,572 (251)
, 1986 SYNTHESIS AND NUCLEAR MAGNETIC RESONANCE STUDIES OF 1,2-DISUBSTITUTED ADAMANTANES (TWO-DIMENSIONAL, NMR, REARRANGEMENTS, EPOXIDE, PROTOADAMANTANE)
ASHRAF NOSHI. ABDEL-SAYED (7989191)
core +4 more sources
Micromachines, 2017 Flexible electronics have attracted great interest in applications for the wearable devices. Flexible solar cells can be integrated into the flexible electronics as the power source for the wearable devices.
Peng Zhou +10 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
MachinesThis paper presents a novel exoskeleton robot that can be used at home to rehabilitate the index fingers of stroke-affected patients. This exoskeleton is designed as a one-degree-of-freedom four-bar mechanism able to guide the human index finger to ...
Tony Punnoose Valayil, Tanio K. Tanev
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Journal of EngineeringA single hybrid meta‐heuristic is presented for the three classical dimensional‐synthesis tasks of the planar four‐bar mechanism, namely path, motion and function generation.
Brian Goueze Tatiekam +3 more
doaj +1 more source
MathematicsThe dimensional synthesis of compliant mechanisms (CMs) leverages the flexibility of their components to achieve precise motion and functionality. This study introduces a novel approach using the parametric fuzzy form of the Freudenstein equation with ...
Ahmed Alhindi, Meng-Sang Chew
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Design Optimization of a Parallel–Serial Manipulator Considering Stiffness Criteria
RoboticsIn this paper, we analyze stiffness and perform geometrical optimization of a parallel–serial manipulator with five degrees of freedom (5-DOF). The manipulator includes a 3-DOF redundantly actuated planar parallel mechanism, whose stiffness determines ...
Anton Antonov
doaj +1 more source