Results 51 to 60 of about 392,357 (290)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Non‐linear dimensionality reduction using fuzzy lattices

open access: yesIET Computer Vision, 2013
The proposed method is based on extraction of non‐linearity from the nearest neighbourhood elements of image. To detect non‐linearity, relation between the nearest neighbourhood elements of the image, have been expressed in terms of Gaussian membership ...
Rajiv Kapoor, Rashmi Gupta
doaj   +1 more source

Nonlinear Dimensionality Reduction Based on HSIC Maximization

open access: yesIEEE Access, 2018
Hilbert-Schmidt independence criterion (HSIC) is typically used to measure the statistical dependence between two sets of data. HSIC first transforms these two sets of data into two reproducing Kernel Hilbert spaces (RKHS), respectively, and then ...
Zhengming Ma   +3 more
doaj   +1 more source

Randomized Dimensionality Reduction for k-means Clustering [PDF]

open access: yes, 2013
We study the topic of dimensionality reduction for $k$-means clustering. Dimensionality reduction encompasses the union of two approaches: \emph{feature selection} and \emph{feature extraction}.
Boutsidis, Christos   +3 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Morphological mapping for non‐linear dimensionality reduction

open access: yesIET Computer Vision, 2015
Recently, much research has been carried out on dimensionality reduction techniques that summarise a large set of features into a smaller set, leading to much less redundancy.
Rajiv Kapoor, Rashmi Gupta
doaj   +1 more source

BIP: A dimensionality reduction for image indexing

open access: yesICT Express, 2019
Searching on internet is one of the daily task done by millions of users around the Globe. There is an urge for effective indexing scheme for unstructured data, which provide better search results. The image, content report, and site pages are said to be
Minu R.I.   +3 more
doaj   +1 more source

Detecting Adversarial Examples through Nonlinear Dimensionality Reduction [PDF]

open access: yes, 2019
Deep neural networks are vulnerable to adversarial examples, i.e., carefully-perturbed inputs aimed to mislead classification. This work proposes a detection method based on combining non-linear dimensionality reduction and density estimation techniques.
Bacciu, Davide   +2 more
core   +1 more source

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