Results 21 to 30 of about 197,285 (307)
eLife, 2022 Cells steadily adapt their membrane glycerophospholipid (GPL) composition to changing environmental and developmental conditions. While the regulation of membrane homeostasis via GPL synthesis in bacteria has been studied in detail, the mechanisms ...
Florian Bleffert +12 more
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Dimerization of Receptor Protein-Tyrosine Phosphatase alpha in living cells
BMC Cell Biology, 2001 Background Dimerization is an important regulatory mechanism of single membrane-spanning receptors. For instance, activation of receptor protein-tyrosine kinases (RPTKs) involves dimerization. Structural, functional and biochemical studies suggested that
Gadella Theodorus WJ +6 more
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Bulletin of the London Mathematical Society, 2016 We give an overview of recent developments in the theory of dimer models. The viewpoint we take is inspired by mirror symmetry. After an introduction to the combinatorics of dimer models, we will first look at dimers in dynamical systems and statistical mechanics, which can be viewed as coming from the A-model in mirror symmetry.
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Computational characterization of dimerization and ligand binding in biological systems [PDF]
, 2013 The self-association of proteins to form dimers or higher-order oligomers is a very common phenomenon in biology. Protein dimerization or oligomerization acts as a control tool for the execution of functions in many biological systems. Three systems were
Zhang, Lixian
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Lipopeptides as dimerization inhibitors of HIV-1 protease [PDF]
, 1999 In AIDS therapy, attempts have been made to inhibit the virus-encoded enzymes, e.g, HIV-1 protease, using active site-directed inhibitors. This approach is questionable, however, due to virus mutations and the high toxicity of the drugs, An alternative ...
Schramm, W. +5 more
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eLife, 2021 Class A G-protein-coupled receptors (GPCRs) normally function as monomers, although evidence from heterologous expression systems suggests that they may sometimes form homodimers and/or heterodimers.
Seksiri Arttamangkul +3 more
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Thermokinetic study of the inactivation reaction of 1-methyl phthalazinium ylids [PDF]
Journal of the Serbian Chemical Society, 2003 The present paper consists in a thermokinetic study on the dimerization reactions of 1-methylphthalazinium ylids with –NO2 (ylid 1) and respectively, –O–CH3 (ylid 2) substituents in the p position of the benzoyl radical bound to the ylidic carbanion ...
Carposu Maria +4 more
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Biomedicines, 2022 Most neurodegenerative diseases have the characteristics of protein folding disorders, i.e., they cause lesions to appear in vulnerable regions of the nervous system, corresponding to protein aggregates that progressively spread through the neuronal ...
Nicolas Papadopoulos +6 more
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Dimer–Dimer Correlations at the Rough–Smooth Boundary
Communications in Mathematical Physics, 2023 AbstractThree phases of macroscopic domains have been seen for large but finite periodic dimer models; these are known as the frozen, rough and smooth phases. The transition region between the frozen and rough region has received a lot of attention for the last twenty years and recently work has been underway to understand the rough–smooth transition ...
Kurt Johansson, Scott Mason
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Lactose and Galactose Promote the Crystallization of Human Galectin-10
Molecules, 2023 Galectin-10 (Gal-10) forms Charcot–Leyden crystals (CLCs), which play a key role in the symptoms of asthma and allergies and some other diseases. Gal-10 has a carbohydrate-binding site; however, neither the Gal-10 dimer nor the CLCs can bind sugars.
Yu-Fan Fu +6 more
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