Results 101 to 110 of about 140,776 (178)
Summary Background and Objectives Achieving sustained drug adherence in psoriasis remains challenging despite effective therapies. This exploratory study aims to investigate the care situation and factors associated with drug adherence in patients with moderate‐to‐severe psoriasis vulgaris (PsO). Patients and Methods A single‐center study was conducted
Negahr Jalili‐Tazeshahri +6 more
wiley +1 more source
Transient hair loss during treatment with dimethyl-fumarate for multiple sclerosis
Introduction Dimethyl-fumarate is a recently approved drug for relapsing-remitting Multiple Sclerosis in Italy. Clinical case A 55-year-old woman started therapy with dimethyl-fumarate on June 2014; it was well-tolerated aside from moderate flushing ...
Nociti, Viviana +3 more
core +1 more source
Prebiotic aqueous reactions catalyzed by native nickel without hydrogen
Serpentinizing (H2‐producing) hydrothermal vents are candidate environments for metabolic origin. They generate highly reducing conditions that convert CO2 to formate and methane in abiotic reactions resembling reactions of the acetyl‐CoA pathway of CO2 fixation. They also contain natural catalysts. Native nickel (Ni0), like Fe0, Co0, and their alloys,
Carolina Garcia Garcia +2 more
wiley +1 more source
Pharmacological activation of Nrf2 attenuated alveolar bone loss and protected periodontal tissues by reducing inflammation and oxidative stress, preserving collagen organization, and favoring bone homeostasis. Reversal of these effects by Nrf2 inhibition further supports Nrf2 signaling as a promising therapeutic target in periodontitis.
Vitória Bonan Costa +8 more
wiley +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Health Literacy and Unmet Needs in Patients With Multiple Sclerosis: A Cross‐Sectional Study
ABSTRACT Aims To identify a correlation between unmet needs and HL levels in people with Multiple Sclerosis (pwMS) and to evaluate how sociodemographic characteristics influence HL levels and unmet needs. Design A cross‐sectional study. Methods The study was conducted using a questionnaire including the HLS19‐Q12 to assess HL and the Long‐term Unmet ...
Francesco Pastore +6 more
wiley +1 more source
Dimethyl Fumarate: A Review in Plaque Psoriasis
Compliance with Ethical StandardsFunding: The preparation of this review was not supported by any external funding.Conflicts of interest: Hannah Blair is a salaried employee of Adis/Springer, is responsible for the article content and declares no ...
Hannah A. Blair (5008301)
core +1 more source
In multiple sclerosis (MS), anti‐CD20 therapies have been associated with increased infection risk, but whether this risk differs between rituximab and ocrelizumab is not known. Using a nationwide cohort, we studied infection risk and relapse outcomes among 16,872 treatment episodes with rituximab, ocrelizumab, or other disease‐modifying therapies ...
Thomas Frisell +2 more
wiley +1 more source
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis
Objective Oral immunotherapies have become a standard treatment in relapsing-remitting multiple sclerosis. Direct comparison of their effect on relapse and disability is needed.Methods We identified all patients with relapsing-remitting multiple ...
D Spitaleri (13311744) +43 more
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