Results 81 to 90 of about 140,776 (178)

Photosensitizing Au(I) Catalysis With Coumarins

Chemistry – A European Journal, EarlyView.
A Au(I) complex with a tethered coumarin fragment was synthesized and characterized by UV‐vis and emission spectroscopy. Its ability to facilitate photo‐driven cross‐coupling reactions through single‐electron and energy transfer events was evaluated. ABSTRACT Gold catalysis shows versatility in a wide range of challenging transformations, wherein light‐
Liliana Capulín Flores, Jacob J. van der Wal, Johannes E. M. N. Klein   +2 more
wiley   +1 more source

Dual‐Functional Polystyrene‐Based Borate Complexes: Recyclable Alkyl Radical Sources and Photodegradable Absorbents

Chemistry – A European Journal, EarlyView.
Dual‐functional polystyrene‐based polymers bearing 2,2′‐(pyridine‐2,6‐diyl)diphenol (PDP) moieties form photoexcitable alkyl borate complexes: (i) As recyclable radical sources, they enable Giese‐type additions with facile purification by reprecipitation and demonstrate proof‐of‐concept for polymer recovery (50% PDP regeneration).
Nami Jimba, Ryosei Ishii, Kazuki Wako, Tomoki Hirohata, Kosuke Sato, Tomohiro Kubo, Kotaro Satoh, Yuto Sumida, Hirohisa Ohmiya, Shinsuke Inagi   +9 more
wiley   +1 more source

Well‐Defined Nickel Precatalysts: Form, Function, and Application

Chemistry – A European Journal, EarlyView.
This review provides guidance on which nickel precatalysts to choose for a given application or which properties to prioritize in reaction development. A summary of the ease of synthesis, stability, diversity, accessibility, modularity, and general applicability is provided along with a related infographic.
Morgan E. John, George A. Koutsantonis, Reto Dorta, Scott G. Stewart   +3 more
wiley   +1 more source

Effect of dimethyl fumarate on renal disease progression in a genetic ortholog of nephronophthisis

, 2018
Dimethyl fumarate is an FDA-approved oral immunomodulatory drug with anti-inflammatory properties that induces the upregulation of the anti-oxidant transcription factor, nuclear factor erythroid-derived factor 2.
Rao, P., Gopala Rangan, Oliver Oey, Magdalena Luciuk, Luciuk, M., Natasha M Rogers, Rangan, G., Padmashree Rao, Priyanka Sagar, Mannix, C., Oey, O., Sagar, P., Rogers, N.M., Carly Mannix, Wong, A., Annette Wong   +15 more
core   +1 more source

Unsaturated biobased polyesters from bicyclic α‐pinene‐based diols

Polymer International, EarlyView.
We present the synthesis of four biosourced unsaturated polyesters made from chiral terpene‐based diols and esters of renewable diacids. The resulting materials harbor a bicyclic pinene ring in their backbones which leads to enhanced thermal properties while still conferring susceptibility to enzyme hydrolysis for chains having a cis alkene.
Ganapathy Ranjani, Shengwei Sun, Erik Sundén, Diana Bernin, Per‐Olof Syrén   +4 more
wiley   +1 more source

Dimethyl fumarate: a new oral treatment option for multiple sclerosis [PDF]

, 2017
Multiple Sclerosis (MS) is a slowly progressive, immunologically mediated disease of the CNS. The recent years have witnessed great efforts in establishing new therapeutic options for multiple sclerosis. There is a clear need for more effective, safe and
Atal, Sarjana S., Atal, Shubham S.
core  

Multiple sclerosis: overview of orally administrated disease-modifying drugs. Do genetics influence the success of treatment?

Neurologijos seminarai, 2019
Multiple sclerosis (MS) is the main cause of acquired neurological disability in the young people. In MS treatment, disease modifying therapies (DMTs) are essential to reduce disease progression by suppressing the inflammatory response responsible for ...
A. Ovčinikova , R. Kizlaitienė
doaj   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

Immunological effects of dimethyl fumarate treatment in blood and CSF of patients with primary progressive MS

, 2021
Dimethyl fumarate is an efficient therapy used widely in patients with relapsing-remitting multiple sclerosis (RRMS). However, lacking effect of treatment has recently been reported in patients with primary progressive MS (PPMS) (Højsgaard Chow et al ...
Højsgaard Chow, H., Sellebjerg, F., Talbot, J., von Essen, M. Rode, Holm Hansen, R.   +4 more
core   +1 more source

A real-world comparison of relapse rates, healthcare costs and resource use among patients with multiple sclerosis newly initiating subcutaneous interferon beta-1a versus oral disease-modifying drugs

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2018
Background Administrative-claims data enable comparative effectiveness assessment using large numbers of patients treated in real-world settings. Objective To evaluate real-world relapses, healthcare costs and resource use in patients with MS newly ...
James D Bowen, Chris M Kozma, Megan M Grosso, Amy L Phillips   +3 more
doaj   +1 more source