Results 51 to 60 of about 556,826 (407)

Cryopreservation of tendon tissue using dimethyl sulfoxide combines conserved cell vitality with maintained biomechanical features.

PLoS ONE, 2019
Biomechanical research on tendon tissue evaluating new treatment strategies to frequently occurring clinical problems regarding tendon degeneration or trauma is of expanding scientific interest.
Eva Hochstrat, Marcus Müller, Andre Frank, Philipp Michel, Uwe Hansen, Michael J Raschke, Daniel Kronenberg, Richard Stange   +7 more
doaj   +1 more source

3-[1-(3-Hydroxybenzyl)-1H-benzimidazol-2-yl]phenol dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2012
Crystals of the title compound were obtained as a 1:1 dimethyl sulfoxide solvate, C20H16N2O2·C2H6O. The molecular conformation of the organic molecule is similar to that in the previously reported unsolvated structure [Eltayeb et al.
Magdalena Quezada-Miriel, Alcives Avila-Sorrosa, Juan Manuel German-Acacio, Reyna Reyes-Martínez, David Morales-Morales   +4 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

2-(5-Bromo-1H-indol-3-yl)-4-(4-bromophenyl)-5-(4-chlorobenzoyl)-1H-pyrrole-3-carbonitrile dimethyl sulfoxide monosolvate

IUCrData, 2016
In the title solvated compound, C26H14Br2ClN3O·C2H6OS, the indole ring is inclined to the central pyrrole ring by 25.7 (2)°. The chlorobenzene ring and the bromobenzene rings subtend dihedral angles of 56.5 (2) and 53.4 (2)°, respectively, with the ...
Y. AaminaNaaz, Jayabal Kamalraja, G. Vimala, Paramasivam T. Perumal, A. SubbiahPandi   +4 more
doaj   +1 more source

A kinetic and theoretical study of the borate catalysed reactions of hydrogen peroxide: the role of dioxaborirane as the catalytic intermediate for a wide range of substrates [PDF]

, 2012
Our recent work has provided new insights into the equilibria and species that exist in aqueous solution at different pHs for the boric acid – hydrogen peroxide system, and the role of these species in oxidation reactions. Most recently, (M. C.
Abel, Adam, Amels, Bennett, Bunton, Chernyshov, Curci, Curci, Curci, D. Martin Davies, Davies, Davies, Davies, Duffin, Durrant, Fortnum, Hansch, Hanson, Hanson, Hoffmann, Hoffmann, Hussain, Ingri, Kamyshny, Lin, Lin, Marcus C. Durrant, Marenich, Maya, Mckillop, McKillop, Michael E. Deary, Mohammad, Muzart, Ogata, Pizer, Salentine, Sawaki, Sawwan, Schubert, Spessard, Wilson, Wilson, Wilson   +43 more
core   +1 more source

Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide

BMB Reports, 2009
Dimethyl sulfoxide (DMSO) is widely used in chemistry and biology as a solvent and as a cryoprotectant. It is also used as a pharmaceutical agent for the treatment of interstitial cystitis and rheumatoid arthritis. Previous reports described DMSO as being reduced by methionine-S-sulfoxide reductase (MsrA).
Kim, Geun-Hee Kwak, Kim Hy, Seung Hee Choi   +3 more
openaire   +4 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

1-Ethyl-4′-(1H-indol-3-ylcarbonyl)-1′-methyl-2,2′′-dioxodispiro[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbonitrile dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2013
In the title compound, C31H25N5O3·C2H6OS, the three indole/indoline units are all essentially planar with maximum deviations of 0.0172 (3), 0.053 (2) and 0.07 (2) Å.
Paramasivam T. Perumal, K. Sethusankar, S. Antony Inglebert, Yuvaraj Arun   +3 more
doaj   +1 more source

The influence of reaction conditions on the Diels-Alder cycloadditions of 2-thio-3-chloroacrylamides; investigation of thermal, catalytic and microwave conditions [PDF]

, 2010
The Diels-Alder cycloadditions of cyclopentadiene and 2,3-dimethyl-1,3-butadiene to a range of 2-thio-3-chloroacrylamides under thermal, catalytic and microwave conditions is described.
Chopra, Jay, Kissane, Marie, Lawrence, Simon E., Lynch, Denis, Maguire, Anita R.   +4 more
core   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source