Results 41 to 50 of about 594 (86)
Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power
Acta Ophthalmologica, Volume 103, Issue 7, Page e511-e523, November 2025.Abstract Purpose
The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.Seyed Mohsen Ebrahimi, Niko Huotari, Ville Saarela, Marja Honkamo, Lauri Raitamaa, Vesa Korhonen, Johanna Tuunanen, Janne Kananen, Vesa Kiviniemi +8 morewiley +1 more sourceÂmir-Ârif ilişkisi: Emir Timur-Yesevîlik örneği
Edeb Erkan
Emir Timur’u anlamak Türkistan, Deşt-i Kıpçak, Doğu Avrupa, Rusya, Kafkasya, İran, Hindistan, Irak, Suriye, Mısır, Türkiye’yi kısaca dünya tarihini anlamaktır.Seyfettin Erşahindoaj +1 more sourcePublic Administration, Local and Regional Governance, and Domestic Terrorism
Public Administration Review, Volume 85, Issue 6, Page 1804-1839, November/December 2025.ABSTRACT
This study examines how the nature of public administration and local and regional governance affects domestic terrorism in 73 mixed and democratic countries from multiple regions and levels of development. In conducting a cross‐national statistical analysis from 1991 to 2019 with standard political, economic, and social controls, and ...Lance Y. Hunter, Wesley L. Meares, Martha H. Ginn, William Hatcher +3 morewiley +1 more source
Dinin Geleceği
Dini Araştırmalar
Din ve dinin geleceği uzun yıllardır akademik ve yerel çevrelerce üzerinde tartışılan temel konuların başında gelmektedir. Bu minvalde tartışmanın bir cephesinde klasik sekülerleşme teorileri yer alırken diğer bir cephede dinin ...Nurhibe Büşra Erdoaj +1 more sourceCerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease
Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.Abstract BACKGROUND
The apolipoprotein E (APOE) gene includes the strongest protective (ε2) and risk (ε4) variants for sporadic Alzheimer's disease (AD), but underlying mechanisms remain unclear. We studied APOE genotype effects on the cerebrospinal fluid (CSF) proteome.Eleonora M. Vromen, Senne B. Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Lars Bertram, Johannes Streffer, Simon Lovestone, Stephanie J. B. Vos, Mikel Tainta, Yvonne Freund‐Levi, Lutz Frölich, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Frans Verhey, Rik Vandenberghe, Jolien Schaeverbeke, Kaj Blennow, Sven J. van der Lee, Philip Scheltens, Yolande A. L. Pijnenburg, Wiesje M. van der Flier, Charlotte E. Teunissen, Henrik Zetterberg, Pieter Jelle Visser, Betty Tijms +26 morewiley +1 more sourceCortical thickness subtypes in cognitively unimpaired individuals: Differential network and transcriptomic vulnerability to cortical thinning
Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.Abstract INTRODUCTION
The emergence, stability, and contributing factors of Alzheimer's disease (AD) gray matter subtypes remain unclear. METHODS
We analyzed data from 1323 individuals without a diagnosis of dementia (CDR < 1) with T1w‐MRI and amyloid‐PET, including 622 with longitudinal data (3.66 ± 1.78 years).Luigi Lorenzini, Mario Tranfa, Leonard Pieperhoff, Federico Masserini, Mara ten Kate, Lyduine E. Collij, Giuseppe Pontillo, Emma S. Luckett, Alle Meije Wink, Henk JMM Mutsaerts, Tiago Gil Oliveira, Daniele Altomare, Mercè Boada, Anouk den Braber, Cindy Birck, Christopher Buckley, Gill Farrar, Wiesje van der Flier, Giovanni B. Frisoni, Rossella Gismondi, Juan Domingo Gispert, Bernard J. Hanseeuw, Frank Jessen, Marta Marquié, Anja Mett, Craig Ritchie, Gemma Salvadó, Michael Schöll, Mahnaz Shekari, Andrew W. Stephens, Betty M. Tijms, David Vállez García, Rik Vandenberghe, Pieter Jelle Visser, Luca Roccatagliata, Neil P. Oxtoby, Matteo Pardini, Frederik Barkhof +37 morewiley +1 more sourceMultiple Antibody‐Coated Gold Nanoparticle‐Based ExoAssay for Rapid Isolation of CNS‐Specific Exosomes From Blood
Journal of Neurochemistry, Volume 169, Issue 10, October 2025.A streamlined nanowire‐based approach (ExoAssay) enabled direct, rapid, and cost‐effective isolation of neuronal extracellular vesicles (EVs) from human plasma using multiple antibody‐coated magnetic nanowires. The isolated EVs were characterized using nanoparticle tracking analysis (NTA), immunoblotting, and transmission electron microscopy (TEM ...Leticia Camila Fernandez Flores, Neelam Younas, Stefan Goebel, Kathrin Dittmar, Tayyaba Saleem, Abrar Younas, Holger Budde, Tobias J. Legler, Wiebke Möbius, Peter Hermann, Matthias Schmitz, Inga Zerr +11 morewiley +1 more sourceUnderstanding barriers and optimizing socio‐cognitive assessment in the diagnosis of neurocognitive disorders
Journal of Neuropsychology, Volume 19, Issue 3, Page 603-618, September 2025.Abstract
Harmonized neuropsychological assessment for neurocognitive disorders (NCDs) is an urgent priority in clinics. Neuropsychology assessments in NCDs seldom include tests exploring social cognitive skills. In 2022, we launched the SIGNATURE initiative to optimize socio‐cognitive assessment in NCDs.Chiara Cerami, Marina Boccardi, Claudia Meli, Andrea Panzavolta, Giulia Funghi, Cristina Festari, Stefano F. Cappa, Thanos Chatzikostopoulos, Christian Chicherio, Florencia Clarens, Fabricio Ferreira de Oliveira, Francesco Di Lorenzo, Marco Filardi, Agustin Ibanez, Nicola Girtler, Thibaud Lebouvier, Giancarlo Logroscino, Antonella Luca, Sarah E. MacPherson, Jordi A. Matias‐Guiu, Tommaso Piccoli, Olivier Piguet, Simone Pomati, Mirella Russo, Leonardo Sacco, Ann‐Katrin Schild, Stefano L. Sensi, Steven D. Shirk, Marc Sollberger, Miguel Tábuas‐Pereira, Magda Tsolaki, Esther van den Berg, Maxime Bertoux, Fiona Kumfor, Jan Van den Stock, Kathleen A. Welsh‐Bohmer, Alessandra Dodich, on behalf of the SIGNATURE initiative +37 morewiley +1 more sourceModernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives
Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.Abstract The landscape of Alzheimer's disease (AD) and related dementias (ADRD) diagnosis is evolving rapidly, driven by advances in disease understanding, biomarker tools, and disease‐modifying therapies. Modern diagnostic approaches emphasize biological precision, early detection, and dynamic frameworks that adapt to treatment‐induced changes in ...Takeshi Iwatsubo, Reisa A. Sperling, Alicia Algeciras‐Schimnich, Hidenori Arai, Anna M. Barron, Tammie L. S. Benzinger, Maria C. Carrillo, Christopher Chen, Seong Hye Choi, Igor C. Fontana, Jonathan Graff‐Radford, Joshua D. Grill, Judith Heidebrink, Chaur‐Jong Hu, Ryoko Ihara, Takeshi Ikeuchi, Atsushi Iwata, Fanny C. F. Ip, Fasihah Irfani Fitri, Clifford R. Jack Jr., Jee Hyang Jeong, Jianping Jia, Nagaendran Kandiah, SangYun Kim, Hisatomo Kowa, Renaud La Joie, Yoshiki Niimi, Ryoji Noritake, Ozioma C. Okonkwo, Sebastian Palmqvist, Michael S. Rafii, Rema Raman, Yong Shen, Tanya Simuni, Heather M. Snyder, Orapitchaya Sriwannopas, Luke E. Stoeckel, Wiesje M. van der Flier, Huali Wang, Donna M. Wilcock, Henrik Zetterberg, Jin Zhou, Simin Mahinrad, Claire E. Sexton +43 morewiley +1 more source