Experimental Basis for the High Oral Toxicity of Dinophysistoxin 1: A Comparative Study of DSP [PDF]
Toxins, 2014 Okadaic acid (OA) and its analogues, dinophysistoxin 1 (DTX1) and dinophysistoxin 2 (DTX2), are lipophilic and heat-stable marine toxins produced by dinoflagellates, which can accumulate in filter-feeding bivalves.
Natalia Vilariño +2 more
exaly +4 more sources
Identification of 24-O-β-d-Glycosides and 7-Deoxy-Analogues of Okadaic Acid and Dinophysistoxin-1 and -2 in Extracts from Dinophysis Blooms, Dinophysis and Prorocentrum Cultures, and Shellfish in Europe, North America and Australasia [PDF]
Toxins, 2021 Two high-mass polar compounds were observed in aqueous side-fractions from the purification of okadaic acid (1) and dinophysistoxin-2 (2) from Dinophysis blooms in Spain and Norway.
Alistair L. Wilkins +12 more
doaj +2 more sources
Journal of Marine Science and Engineering, 2021 Diarrhetic shellfish poisoning (DSP) is a globally occurring disease threatening public health and trade. The causative toxins, okadaic acid (OA), dinophysistoxin-1 (DTX1), and dinophysistoxin-2 (DTX2) are collectively called OAs, and are quantified ...
Tsuyoshi Ikehara +2 more
doaj +2 more sources
Toxic Action Reevaluation of Okadaic Acid, Dinophysistoxin-1 and Dinophysistoxin-2: Toxicity Equivalency Factors Based on the Oral Toxicity Study [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Okadaic acid (OA) and the structurally related compounds dinophysistoxin-1 (DTX1) and dinophysistoxin-2 (DTX2) are marine phycotoxins that cause diarrheic shellfish poisoning (DSP) in humans due to ingestion of contaminated shellfish. In
Paula Abal +8 more
doaj +2 more sources
Integrated Multi-Omics Analysis Reveals Complex Cytotoxicity-Associated Molecular Response Patterns of Representative Toxins from Four Classes of Lipophilic Algal Toxins in Neuro-2a Cells [PDF]
ToxinsLipophilic marine toxins (LMTs) are important toxic risk factors in marine ecosystems and seafood safety, yet the comparative cytotoxicity-associated molecular responses of different LMT classes remain unclear.
Xueru Wei +5 more
doaj +2 more sources
Lipophilic Shellfish Poisoning Toxins in Marine Invertebrates from the Galician Coast [PDF]
Toxins, 2023 For the purpose of assessing human health exposure, it is necessary to characterize the toxins present in a given area and their potential impact on commercial species.
Araceli E. Rossignoli +7 more
doaj +2 more sources
Quantitation of diarrhetic shellfish poisoning toxins in Chilean Mussel using pyrenyldiazomethane as fluorescent labeling reagent [PDF]
Biological Research, 2003 Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by lipid soluble polyether toxins produced by dinoflagellates and accumulated in shellfish.
CARLOS GARCÍA +3 more
doaj +2 more sources
Okadaic Acid Is at Least as Toxic as Dinophysistoxin-1 after Repeated Administration to Mice by Gavage. [PDF]
Toxins (Basel), 2023 Okadaic acid (OA) and its analogues cause diarrhetic shellfish poisoning (DSP) in humans, and risk assessments of these toxins require toxicity equivalency factors (TEFs), which represent the relative toxicities of analogues.
Park SY +6 more
europepmc +2 more sources
Magnetic Covalent Organic Framework Composites for Wastewater Remediation
Small, Volume 19, Issue 37, September 13, 2023., 2023 Covalent organic frameworks (COFs) have desirable properties but their powder form hinders practical applications. This review focuses on magnetic COFs and their applications in wastewater treatment. The review highlights the structural parameters that impact adsorption performance, and discusses the challenges and future prospects in the field ...
Juan Yang +3 more
wiley +1 more source
Journal of Phycology, Volume 59, Issue 4, Page 658-680, August 2023., 2023 Abstract Multiple species of the genus Dinophysis produce diarrhetic shellfish toxins (okadaic acid and Dinophysis toxins, OA/DTXs analogs) and/or pectenotoxins (PTXs). Only since 2008 have DSP events (illnesses and/or shellfish harvesting closures) become recognized as a threat to human health in the United States.
Nour Ayache +17 more
wiley +1 more source