Results 141 to 150 of about 888 (178)
METABOLIC TRANSFORMATION OF DINOPHYSISTOXIN-3 INTO DINOPHYSISTOXIN-1 CAUSES HUMAN INTOXICATION BY CONSUMPTION OF O-ACYL-DERIVATIVES DINOPHYSISTOXINS CONTAMINATED SHELLFISH [PDF]
Journal of Toxicological Sciences, 2005 This paper describes for the first time a massive intoxication episode due to consumption of shellfish contaminated with 7-O-acyl-derivative dinophysistoxin-1, named Dinophysistoxin-3 (DTX-3).
Juan Carlos Diaz
exaly +6 more sources
Toxicology in Vitro, 2015 10.1016/j.tiv.2014.09.002Marine dinoflagelates from the genus Dynophisis are important producers of Diarrhetic Shellfish Poisoning (DSP) toxins which are responsible for human intoxications.
Lucia Solino +2 more
exaly +4 more sources
Comparative toxicity of dinophysistoxin-1 and okadaic acid in mice
Journal of Veterinary Medical Science, 2018 The mouse bioassay for diarrhetic shellfish poisoning toxins has been used worldwide. In this study, dinophysistoxin-1 (DTX-1) and okadaic acid (OA) were compared for toxicity. The lethality rate increased and the median survival time decreased in a dose-dependent manner in both DTX-1 and OA. The median lethal dose value was 150.4 µg/kg (95% confidence
Hodaka Suzuki
exaly +5 more sources
Diarrhetic Shellfish Toxin, Dinophysistoxin-1, Is a Potent Tumor Promoter on Mouse Skin [PDF]
Japanese Journal of Cancer Research, 1988 Dinophysistoxin‐1, 35‐methylokadaic acid, is a causative agent of diarrhetic shellfish poisoning. The biological activities and tumor‐promoting activity of dinophysistoxin‐1 were studied together with those of okadaic acid and 7‐O‐palmitoyl okadaic acid.
Hirota Fujiki +2 more
exaly +3 more sources
First evidence of Dinophysistoxin-1 ester and carcinogenic polycyclic aromatic hydrocarbons in smoked bivalves collected in the Patagonia fjords [PDF]
Toxicon, 2004 Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by fat-soluble polyether toxins produced by dinoflagellates and accumulated in shellfish.
González, Viviana +4 more
exaly +2 more sources
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Journal of Agricultural and Food Chemistry, 2013
The protein phosphatase inhibition assay (PPIA) is a well-known strategy for the determination of diarrheic shellfish poisoning (DSP) lipophilic toxins, which deserves better characterization and understanding to be used as a routine screening tool in monitoring programs. In this work, the applicability of two PPIAs to the determination of okadaic acid
Mònica Campàs +2 more
exaly +3 more sources
The protein phosphatase inhibition assay (PPIA) is a well-known strategy for the determination of diarrheic shellfish poisoning (DSP) lipophilic toxins, which deserves better characterization and understanding to be used as a routine screening tool in monitoring programs. In this work, the applicability of two PPIAs to the determination of okadaic acid
Mònica Campàs +2 more
exaly +3 more sources
Journal of Chromatography A, 2005
A rapid and simple method for confirmation of the diarrhetic shellfish poisons (DSP): okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2) using fluorescence detection following derivatization with 9-chloromethylanthracene, has been established as an alternate to LC/MS.
Rawn, Dorothea F. K. +7 more
openaire +3 more sources
A rapid and simple method for confirmation of the diarrhetic shellfish poisons (DSP): okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2) using fluorescence detection following derivatization with 9-chloromethylanthracene, has been established as an alternate to LC/MS.
Rawn, Dorothea F. K. +7 more
openaire +3 more sources
Dinophysistoxin-2: The predominant diarrhoetic shellfish toxin in Ireland
Toxicon, 1996Diarrhoetic shellfish poisoning (DSP) in Europe is due mainly to the presence of the dinoflagellate toxin, okadaic acid (OA). However, analysis of cultivated mussels (Mytilus edulis) from southwest Ireland revealed that an isomer of OA, dinophysistoxin-2, was the major toxin present during DSP episodes. Using fluorimetric HPLC, following derivatisation
E P, Carmody, K J, James, S S, Kelly
openaire +2 more sources
Effects of marine phycotoxin dinophysistoxin-1 on the growth and cell cycle of Isochrysis galbana
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2023The phycotoxin dinophysistoxins are widely distributed in the global marine environments and potentially threaten marine organisms and human health. The mechanism of the dinophysistoxin toxicity in inhibiting the growth of microalgae is less well understood.
Lilin, Han +6 more
openaire +2 more sources
Dinophysistoxin-2: a rare diarrhoeic toxin associated with Dinophysis acuta
Toxicon, 2000Okadaic acid and dinophysistoxin-2 have been found yearly in Portuguese shellfish. Their presence was correlated with the occurrence of Dinophysis spp: Dinophysis acuminata has until now been found to be responsible only for OA contamination, while Dinophysis acuta contributes with OA and the rare diarrhetic toxin DTX2.
P, Vale, M A, Sampayo
openaire +2 more sources