Results 121 to 130 of about 5,720 (220)

Bioengineering of Important Secondary Metabolites and Metabolic Pathways in Fenugreek (Trigonella foenum-graecum L.)

Journal of Medicinal Plants, 2010
Fenugreek (Trigonella foenum-graecum L.) has a long and respected history of medicinal uses in Middle East and Persian medicine. The hypocholesterolaemic and hypoglycaemic effects of fenugreek were attributed to its major steroidal sapogenin, diosgenin ...
A Mehrafarin, A Qaderi, Sh Rezazadeh, H Naghdi Badi, Gh Noormohammadi, E Zand   +5 more
doaj  

Diosgenin Attenuates Photoreceptor Degeneration in an N-Methyl-N-Nitrosourea-Induced Mouse Model of Retinal Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Tong W, Cao J, Zhou X, Jia B, Li D, Fu J.   +5 more
europepmc   +1 more source

Diosgenin ameliorates testicular damage in streptozotocin-diabetic rats through attenuation of apoptosis, oxidative stress, and inflammation

, 2019
Diabetes mellitus (DM) is a prevalent metabolic disorder that is associated with development of some complications in male reproductive system including testicular damage, sexual dysfunction, abnormal spermatogenesis, and infertility.
Baluchnejadmojarad, T., Roghani, M., Sedaghat, R., Khosravi, Z.   +3 more
core  

Network Pharmacology, Molecular Docking and Dynamics Simulation Reveal the Anti-Colitis Mechanism of <i>Smilax glabra</i> Roxb. [PDF]

Clin Exp Gastroenterol
Cui Y, Hu J, Li Y, Tong Y, Shen H.
europepmc   +1 more source

Functional characterization of four glycosyltransferases for biosynthesis of steroidal saponins in medicinal plant <i>Paris polyphylla</i>. [PDF]

Synth Syst Biotechnol
Subthain H, Guo F, Zhang C, Fang P, Zhang L, Su Q, Tang D, Chi L, Liu C, Urlacher VB, Li J, Du L, Li S.   +12 more
europepmc   +1 more source

Network Pharmacology and Molecular Docking-Based Approach Revealing the Potential Anticancer Compounds and Molecular Mechanisms of <i>Paris polyphylla</i> Against Colorectal Cancer. [PDF]

Int J Mol Sci
Khanaree C, Inpan R, Taychaworaditsakul W, Dukeaw N.   +3 more
europepmc   +1 more source

Diosgenin-mediated NF-κB and MAPK pathway modulation for osteoarthritis treatment: molecular mechanisms, bioavailability enhancement, and therapeutic applications. [PDF]

Inflammopharmacology
Adarkar R, Viswambharan VL, Dessai A, Lobo R, Tippavajhala VK, Pai V, Subraya CK, Aswatha Ram HN.   +7 more
europepmc   +1 more source

Structural basis for diosgenin as an inverse agonist of retinoic acid receptor-related orphan receptor γ. [PDF]

Sci Rep
Chen S, Tian S, Liang J, Wang R, Li Y.
europepmc   +1 more source

Diosgenin Mitigates Streptozotocin Diabetes-induced Vascular Dysfunction of the Rat Aorta: The Involved Mechanisms

, 2015
Chronic diabetes mellitus finally leads to serious vascular dysfunction. Diosgenin is a natural steroidal saponin with potential cardiovascular protective effect.
Baluchnejadmojarad, T., Roghani, M., Roghani-Dehkordi, F.   +2 more
core  

Risks, Benefits, and Molecular Targets of Fenugreek Administration in the Treatment of Hepatocellular Carcinoma. [PDF]

Cancers (Basel)
Vittal M, Menegassi B, Vinciguerra M.
europepmc   +1 more source