Altering Sterol Composition Implied That Cholesterol Is Not Physiologically Associated With Diosgenin Biosynthesis in Trigonella foenum-graecum [PDF]
Diosgenin serves as an important precursor of most steroidal drugs in market. Cholesterol was previously deemed as a sterol origin leading to diosgenin biosynthesis.
Yansheng Zhang +2 more
exaly +7 more sources
Comparative Transcriptome Analysis Identifies Genes Involved in Diosgenin Biosynthesis in Trigonella foenum-graecum L. [PDF]
Trigonella foenum-graecum L. (fenugreek) is a valuable resource of producing diosgenin which serves as a substrate for synthesizing more than two hundred kinds of steroidal drugs.
Yansheng Zhang, Zhou Chen, Changfu Li
exaly +7 more sources
TfWRKY40 positively regulates diosgenin biosynthesis in Trigonella foenum-graecum L. [PDF]
Diosgenin is a bioactive steroidal natural product extraced from plants and serves as an important precursor for the industrial production of steroidal hormone drugs.
Yansheng Zhang +2 more
exaly +6 more sources
Diosgenin biosynthesis pathway and its regulation in Dioscorea cirrhosa L. [PDF]
Dioscorea cirrhosa L. (D. cirrhosa) tuber is a traditional medicinal plant that is abundant in various pharmacological substances. Although diosgenin is commonly found in many Dioscoreaceae plants, its presence in D. cirrhosa remained uncertain.
Yan Lin +6 more
doaj +5 more sources
Silymarin and serotonin, individually and synergistically, enhance fenugreek resistance to salt stress by modulating pathways involved in chlorophyll biosynthesis, defense system, hormonal regulation, ion redox balance, and diosgenin production [PDF]
Background Salinity stress, as one of the most significant and widespread abiotic stresses, affects a large portion of the world’s arable lands. Developing salt-tolerant plants through classical breeding, biotechnology, and molecular methods is time ...
Sajedeh Roshandel +2 more
doaj +5 more sources
Salinity-induced stress is widely considered a main plant-growth-limiting factor. The positive effects of melatonin in modulating abiotic stresses have led this hormone to be referred to as a growth regulator in plants.
Amin Ebrahimi +2 more
exaly +5 more sources
Next-generation sequencing of representational difference analysis products for identification of genes involved in diosgenin biosynthesis in fenugreek (Trigonella foenum-graecum) [PDF]
Representational difference analysis of cDNA was performed and differential products were sequenced and annotated. Candidate genes involved in biosynthesis of diosgenin in fenugreek were identified. Detailed mechanism of diosgenin synthesis was proposed. Fenugreek (Trigonella foenum-graecum L.) is a valuable medicinal and crop plant.
Magdalena Szeliga +2 more
exaly +6 more sources
The Functional Characterization of DzCYP72A12-4 Related to Diosgenin Biosynthesis and Drought Adaptability in Dioscorea zingiberensis. [PDF]
Dioscorea zingiberensis is a perennial herb famous for the production of diosgenin, which is a valuable initial material for the industrial synthesis of steroid drugs. Sterol C26-hydroxylases, such as TfCYP72A616 and PpCYP72A613, play an important role in the diosgenin biosynthesis pathway.
Wang W, Hou L, Li S, Li J.
europepmc +3 more sources
An HD-ZIP I Transcription Factor DZHDZ32 Upregulates Diosgenin Biosynthesis in <i>Dioscorea zingiberensis</i>. [PDF]
Diosgenin, a crucial precursor for steroidal drug production, has poorly understood regulatory pathways. Diosgenin is the primary active component of Dioscorea zingiberensis. Notably, D. zingiberensis also possesses the highest diosgenin content among Dioscorea species, reaching up to 16.15% of dry weight.
Yang H, Li Y, Hu Z, Li J.
europepmc +3 more sources
High-temperature stress is widely considered a main plant-growth-limiting factor. The positive effects of 24-epibrassinolide (EBR) as analogs of brassinosteroids (BRs) in modulating abiotic stresses have led this hormone to be referred to as a growth ...
Shahla Sheikhi +5 more
doaj +3 more sources

