Results 41 to 50 of about 1,104 (142)

Development of a New High-Cell Density Fermentation Strategy for Enhanced Production of a Fungus β-Glucosidase in Pichia pastoris

open access: yesFrontiers in Microbiology, 2020
Traditional diosgenin manufacturing process has led to serious environmental contamination and wastewater. Clean processes are needed that can alternate the diosgenin production. The β-glucosidase FBG1, cloned from Fusarium sp.
Wancang Liu   +8 more
doaj   +1 more source

Metabolome Profiling of Eight Chinese Yam (Dioscorea polystachya Turcz.) Varieties Reveals Metabolite Diversity and Variety Specific Uses

open access: yesLife, 2021
The Chinese yam (Dioscorea polystachya Turcz.) is an underutilized orphan tuber crop. However, in China it has been used in traditional medicine and food for centuries due to the presence of high starch, protein, fiber, and biologically active compounds.
Xiaoxuan Zeng, Dahui Liu, Luqi Huang
doaj   +1 more source

Cloning, characterization, and expression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene from Dioscorea zingiberensis

open access: yesBiologia Plantarum, 2019
Diosgenin, mainly extracted from some Dioscorea species, is the most important starting material for the production of steroidal drugs. It is believed that diosgenin in Dioscorea is synthesized from isopentenyl diphosphate (IPP) and dimethylallyl ...
Z. Cheng   +4 more
doaj   +1 more source

Elicitation of diosgenin production in Trigonella foenum-graecum (fenugreek) seedlings by methyl jasmonate [PDF]

open access: yes, 2015
The effects of methyl jasmonate (MeJA), an elicitor of plant defense mechanisms, on the biosynthesis of diosgenin, a steroidal saponin, were investigated in six fenugreek (Trigonella foenum-graecum) varieties (Gujarat Methi-2, Kasuri-1, Kasuri-2, Pusa ...
A. Chaudhary   +19 more
core   +1 more source

Ethylene treatment improves diosgenin accumulation in in vitro cultures of Dioscorea zingiberensis via up-regulation of CAS and HMGR gene expression [PDF]

open access: yes, 2013
Background: The perennial medicinal herb Dioscorea zingiberensis is a very important plant used for steroid drug manufacturing for its high level of diosgenin in rhizome. Although the stimulation of diosgenin accumulation by ethylene has been reported in
He, Ji   +7 more
core   +1 more source

Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek

open access: yes, 2023
Fenugreek (Trigonella foenum-graecum L.) is one of the medicinal plants traditionally used in human nutrition and being used as medicine due to the presence of an active substance called diosgenin.
Sina Majidian   +3 more
core   +1 more source

Advances in the Biosynthesis and Molecular Evolution of Steroidal Saponins in Plants

open access: yes, 2023
Steroidal saponins are an important type of plant-specific metabolite that are essential for plants’ responses to biotic and abiotic stresses. Because of their extensive pharmacological activities, steroidal saponins are also important industrial ...
Huan Yang   +4 more
core   +1 more source

Natural Compounds Diosgenin and Panaxadiol Exhibit Anti-Cancer Activities, Potentially Through Targeting RORγ [PDF]

open access: yes, 2023
My study explores the potential anticancer properties of primarily two natural small molecule compounds, diosgenin and panaxadiol, in relation to Retinoic Acid Receptor-related Orphan Receptor Gamma (RORγ)-mediated cancer pathways.
Sharma, Shreya
core  

A hairy-root transformation protocol for Trigonella foenum-graecum L. as a tool for metabolic engineering and specialised metabolite pathway elucidation [PDF]

open access: yes, 2020
The development of genetic transformation methods is critical for enabling the thorough characterization of an organism and is a key step in exploiting any species as a platform for synthetic biology and metabolic engineering approaches.
Alain Goossens   +15 more
core   +2 more sources

Data_Sheet_1_Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.PDF

open access: yes, 2021
Fenugreek (Trigonella foenum-graecum), a pharmacologically important herb, is widely known for its antidiabetic, hypolipidemic, and anticancer effects. The medicinal properties of this herb are accredited to the presence of bioactive steroidal saponins ...
Yansheng Zhang (465719)   +4 more
core   +1 more source

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