Results 41 to 50 of about 239,005 (157)
Preparation Of Diosgenin-Encapsulated Microspheres By Spray Drying Technique
, 2023 Diosgenin, a naturally occurring steroid sapogenin possessing diverse therapeutic properties, represents a bioactive compound of interest. However, its complete pharmaceutical utilization has been impeded by inherent challenges, primarily associated with
Mangla, Mohit +3 more
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Yeast, EarlyView.We present cryoBN‐PAGE, a method that enables blue native polyacrylamide gel electrophoresis analysis of mitochondrial respiratory complexes and supercomplexes directly from whole yeast cells using cryogenic milling. This approach eliminates the need for mitochondrial isolation, reducing time and cost while preserving native protein complexes.
Lizeth J. Camacho Lopez +3 more
wiley +1 more source
Natural Compounds Diosgenin and Panaxadiol Exhibit Anti-Cancer Activities, Potentially Through Targeting RORγ [PDF]
, 2023 My study explores the potential anticancer properties of primarily two natural small molecule compounds, diosgenin and panaxadiol, in relation to Retinoic Acid Receptor-related Orphan Receptor Gamma (RORγ)-mediated cancer pathways.
Sharma, Shreya
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The Effects of Diosgenin on Hypolipidemia and Its Underlying Mechanism: A Review
Diabetes, Metabolic Syndrome and Obesity, 2021 Fengcui Sun,1 Xiufen Yang,1 Chaoqun Ma,1 Shizhao Zhang,1 Lu Yu,2 Haifei Lu,3 Guoliang Yin,1 Pengpeng Liang,1 Yanan Feng,1 Fengxia Zhang4 1Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2Tianjin University ...
Sun F +9 more
doaj
CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.In aged rats, 6‐month SXZ treatment reversed spatial memory deficits and preserved hippocampal integrity. Mechanistic assays show that SXZ promotes glutathione metabolism and inhibits ferroptosis via p53/SLC7A11/GPX4 and Keap1/Nrf2/HO‐1 pathways. SXZ is a novel neuroprotective agent against age‐related cognitive decline.
Mengya Liu +6 more
wiley +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source
Molecules, 2018 Dioscorea zingiberensis is a perennial herb native to China. The rhizome of D. zingiberensis has long been used as a traditional Chinese medicine to treat rheumatic arthritis.
Jia Li +4 more
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MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source
Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek
, 2023 Fenugreek (Trigonella foenum-graecum L.) is one of the medicinal plants traditionally used in human nutrition and being used as medicine due to the presence of an active substance called diosgenin.
Sina Majidian +3 more
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Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source