Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
Pharmaceutical Crops: An Overview [PDF]
Pharmaceutical crops is an ambiguous term used by biologists and chemists for different categories of plants. We define pharmaceutical crops as those cultivated species that are used for extraction or preparation of therapeutic substances such as active ...
Antoun, Mikhail +5 more
core +1 more source
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
Natural inhibitors of pancreatic lipase as new players in obesity treatment [PDF]
Obesity is a multifactorial disease characterized by an excessive weight for height due to an enlarged fat deposition such as adipose tissue, which is attributed to a higher calorie intake than the energy expenditure.
Boque, Noemi +4 more
core +1 more source
Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha [PDF]
The oxysterol-activated nuclear receptor liver X receptor alpha (LXR alpha) has been implicated in the control of both cholesterol and fatty acid metabolism.
Bloks, Vincent W. +4 more
core +2 more sources
Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su +5 more
wiley +1 more source
Callogenèse et néoformation chez deux espèces de Dioscorea comestibles : D. alata et D. trifida [PDF]
La création d'une diversité génétique est nécessaire pour l'amélioration variétale des ignames. La sélection par hybridation est limitée par l'irrégularité ou même l'absence de fructification des clones cultivés.
Chaguardieff, P. +2 more
core
The red resin of Dracaena cochinchinensis (Lour.) S.C. Chen, known as Chinese dragon’s blood, is formed through metabolic reprogramming following trunk injury, during which the original steroidal saponins are depleted and transformed.
Bin Dai, Li Wang, Li-Hua Su, Hai-Zhou Li
doaj +1 more source
A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review [PDF]
Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. Over the long period of evolution, some co-existing endophytes and their host plants have established a ...
Abd_Allah +141 more
core +1 more source
Carbon isotopic (C-13 and C-14) composition of synthetic estrogens and progestogens [PDF]
RATIONALE: Steroids are potent hormones that are found in many environments. Yet, contributions from synthetic and endogenous sources are largely uncharacterized.
Aelion +55 more
core +2 more sources

