Results 21 to 30 of about 1,074 (118)

Identification and Characterization of a Trillin Rhamnosyltransferase From Dioscorea zingiberensis

Frontiers in Plant Science, 2021
Dioscorea zingiberensis accumulates abundant steroidal saponins, such as dioscin, which is the principal bioactive ingredient displaying a wide range of pharmacological activities.
Jia Li, Isidore Mosongo, Han Li, Yalun Wu, Changfu Li, Shihui Yang, Yansheng Zhang   +6 more
doaj   +1 more source

Diosgenin Biosynthesis in the Sprouts of Fenugreek as Influenced by Chitosan [PDF]

OnLine Journal of Biological Sciences, 2019
Trigonella foenum-graecum L. (Fabaceae), known as Fenugreekis an annual herb, contains various secondary metabolites including steroidal saponins, flavonoids, phenolic compounds and alkaloids. This study was planned to investigate the effect of concentrations of chitosan on growth, expression of diosgenin biosynthetic genes and diosgenin accumulation ...
Do Yeon Kwon, Jae Kwang Kim, Sang Un Park   +2 more
openaire   +1 more source

Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum

Frontiers in Plant Science, 2021
Fenugreek (Trigonella foenum-graecum), a pharmacologically important herb, is widely known for its antidiabetic, hypolipidemic, and anticancer effects. The medicinal properties of this herb are accredited to the presence of bioactive steroidal saponins ...
Jianghong Gao, Yehan Xu, Congkun Hua, Changfu Li, Yansheng Zhang   +4 more
doaj   +1 more source

The genome of Dioscorea zingiberensis sheds light on the biosynthesis, origin and evolution of the medicinally important diosgenin saponins

Horticulture Research, 2022
Abstract Diosgenin saponins isolated from Dioscorea species such as D. zingiberensis exhibit a broad spectrum of pharmacological activities. Diosgenin, the aglycone of diosgenin saponins, is an important starting material for the production of steroidal drugs. However, how plants produce diosgenin saponins and the origin and evolution of
Li, Yi, Tan, Chao, Li, Zihao, Guo, Jingzhe, Li, Song, Chen, Xin, Wang, Chen, Dai, Xiaokang, Yang, Huan, Song, Wei, Hou, Lixiu, Xu, Jiali, Tong, Ziyu, Xu, Anran, Yuan, Xincheng, Wang, Weipeng, Yang, Qingyong, Chen, Lingling, Sun, Zongyi, Wang, Kai, Pan, Bo, Chen, Jianghua, Bao, Yinghua, Liu, Faguang, Qi, Xiaoquan, Gang, David R, Wen, Jun, Li, Jiaru   +27 more
openaire   +2 more sources

Bio-Assisted Synthesis of Reduced Graphene Oxide Nanosheets From Graphene Oxide: Promising and Efficient Cytotoxic and Antidiabetic Potency in In Vitro, Kinetic, and In Silico Models. [PDF]

Int J Biomater
Green chemistry has recently made strides in the sustainable synthesis of next‐generation nanomaterials using reducing agents sourced from plants. Biocompatible conversion of reduced graphene oxide from graphene oxide nanomaterials is of particular interest in medical applications. The leaf extract of C.
Yadav M, Vashishth D, Bhardwaj M, Yadav JP, Kataria SK.   +4 more
europepmc   +2 more sources

Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus. [PDF]

Chem Biodivers
Analysis of the chemical profile and antiviral potential of Costus arabicus L. extracts. ABSTRACT Widely used in Brazilian folk medicine, Costus arabicus L. (Canarana) is a herbaceous plant with promising pharmacological potential. Here, we profile the molecular composition of extracts from different plant organs and evaluate their in vitro activity ...
Carvalho ARV, Reis JDE, Ferraz AC, da Silva Menegatto MB, da C Lopes J, Pamplona SDGSR, da Silva MN, de Brito Magalhães CL, Gomes PWP, Yoshioka E Silva CY.   +9 more
europepmc   +2 more sources

Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells [PDF]

Biochemical Journal, 1984
The aglycon form of the steroidal sapogenin furost −5-ene-3 beta, 22,26-triol, 3 beta- chacotrioside 26 beta-D-glucopyranoside was isolated from cell suspension cultures of Dioscorea deltoidea and its molecular structure was determined by mass spectrometry and 1H and 13C n.m.r. spectroscopy.
B, Tal, I, Tamir, J S, Rokem, I, Goldberg   +3 more
openaire   +2 more sources

Development of a New High-Cell Density Fermentation Strategy for Enhanced Production of a Fungus β-Glucosidase in Pichia pastoris

Frontiers in Microbiology, 2020
Traditional diosgenin manufacturing process has led to serious environmental contamination and wastewater. Clean processes are needed that can alternate the diosgenin production. The β-glucosidase FBG1, cloned from Fusarium sp.
Wancang Liu, Haibo Xiang, Haibo Xiang, Tao Zhang, Xu Pang, Jing Su, Hongyu Liu, Baiping Ma, Liyan Yu   +8 more
doaj   +1 more source

Exploring the medicinally important secondary metabolites landscape through the lens of transcriptome data in fenugreek (Trigonella foenum graecum L.)

Scientific Reports, 2022
Fenugreek (Trigonella foenum-graecum L.) is a self-pollinated leguminous crop belonging to the Fabaceae family. It is a multipurpose crop used as herb, spice, vegetable and forage.
Mahantesha B. N. Naika, Nitish Sathyanarayanan, Radha Sivarajan Sajeevan, Teerna Bhattacharyya, Pritha Ghosh, Meenakshi S. Iyer, Mahita Jarjapu, Adwait G. Joshi, K. Harini, K. Mohamed Shafi, Neha Kalmankar, Snehal D. Karpe, Bhavika Mam, Shaik Naseer Pasha, Ramanathan Sowdhamini   +14 more
doaj   +1 more source

Metabolome Profiling of Eight Chinese Yam (Dioscorea polystachya Turcz.) Varieties Reveals Metabolite Diversity and Variety Specific Uses

Life, 2021
The Chinese yam (Dioscorea polystachya Turcz.) is an underutilized orphan tuber crop. However, in China it has been used in traditional medicine and food for centuries due to the presence of high starch, protein, fiber, and biologically active compounds.
Xiaoxuan Zeng, Dahui Liu, Luqi Huang
doaj   +1 more source