Results 21 to 30 of about 1,995 (163)

The origin and evolution of the diosgenin biosynthetic pathway in yam

Plant Communications, 2021
Diosgenin, mainly produced by Dioscorea species, is a traditional precursor of most hormonal drugs in the pharmaceutical industry. The mechanisms that underlie the origin and evolution of diosgenin biosynthesis in plants remain unclear.
Jian Cheng, Jing Chen, Xiaonan Liu, Xiangchen Li, Weixiong Zhang, Zhubo Dai, Lina Lu, Xiang Zhou, Jing Cai, Xueli Zhang, Huifeng Jiang, Yanhe Ma   +11 more
doaj   +1 more source

Identification and Characterization of a Trillin Rhamnosyltransferase From Dioscorea zingiberensis

Frontiers in Plant Science, 2021
Dioscorea zingiberensis accumulates abundant steroidal saponins, such as dioscin, which is the principal bioactive ingredient displaying a wide range of pharmacological activities.
Jia Li, Isidore Mosongo, Han Li, Yalun Wu, Changfu Li, Shihui Yang, Yansheng Zhang   +6 more
doaj   +1 more source

Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum

Frontiers in Plant Science, 2021
Fenugreek (Trigonella foenum-graecum), a pharmacologically important herb, is widely known for its antidiabetic, hypolipidemic, and anticancer effects. The medicinal properties of this herb are accredited to the presence of bioactive steroidal saponins ...
Jianghong Gao, Yehan Xu, Congkun Hua, Changfu Li, Yansheng Zhang   +4 more
doaj   +1 more source

Diosgenin Biosynthesis in the Sprouts of Fenugreek as Influenced by Chitosan [PDF]

OnLine Journal of Biological Sciences, 2019
Trigonella foenum-graecum L. (Fabaceae), known as Fenugreekis an annual herb, contains various secondary metabolites including steroidal saponins, flavonoids, phenolic compounds and alkaloids. This study was planned to investigate the effect of concentrations of chitosan on growth, expression of diosgenin biosynthetic genes and diosgenin accumulation ...
Do Yeon Kwon, Jae Kwang Kim, Sang Un Park   +2 more
openaire   +1 more source

The genome of Dioscorea zingiberensis sheds light on the biosynthesis, origin and evolution of the medicinally important diosgenin saponins

Horticulture Research, 2022
Abstract Diosgenin saponins isolated from Dioscorea species such as D. zingiberensis exhibit a broad spectrum of pharmacological activities. Diosgenin, the aglycone of diosgenin saponins, is an important starting material for the production of steroidal drugs. However, how plants produce diosgenin saponins and the origin and evolution of
Li, Yi, Tan, Chao, Li, Zihao, Guo, Jingzhe, Li, Song, Chen, Xin, Wang, Chen, Dai, Xiaokang, Yang, Huan, Song, Wei, Hou, Lixiu, Xu, Jiali, Tong, Ziyu, Xu, Anran, Yuan, Xincheng, Wang, Weipeng, Yang, Qingyong, Chen, Lingling, Sun, Zongyi, Wang, Kai, Pan, Bo, Chen, Jianghua, Bao, Yinghua, Liu, Faguang, Qi, Xiaoquan, Gang, David R, Wen, Jun, Li, Jiaru   +27 more
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Exploring the medicinally important secondary metabolites landscape through the lens of transcriptome data in fenugreek (Trigonella foenum graecum L.)

Scientific Reports, 2022
Fenugreek (Trigonella foenum-graecum L.) is a self-pollinated leguminous crop belonging to the Fabaceae family. It is a multipurpose crop used as herb, spice, vegetable and forage.
Mahantesha B. N. Naika, Nitish Sathyanarayanan, Radha Sivarajan Sajeevan, Teerna Bhattacharyya, Pritha Ghosh, Meenakshi S. Iyer, Mahita Jarjapu, Adwait G. Joshi, K. Harini, K. Mohamed Shafi, Neha Kalmankar, Snehal D. Karpe, Bhavika Mam, Shaik Naseer Pasha, Ramanathan Sowdhamini   +14 more
doaj   +1 more source

Metabolome Profiling of Eight Chinese Yam (Dioscorea polystachya Turcz.) Varieties Reveals Metabolite Diversity and Variety Specific Uses

Life, 2021
The Chinese yam (Dioscorea polystachya Turcz.) is an underutilized orphan tuber crop. However, in China it has been used in traditional medicine and food for centuries due to the presence of high starch, protein, fiber, and biologically active compounds.
Xiaoxuan Zeng, Dahui Liu, Luqi Huang
doaj   +1 more source

Development of a New High-Cell Density Fermentation Strategy for Enhanced Production of a Fungus β-Glucosidase in Pichia pastoris

Frontiers in Microbiology, 2020
Traditional diosgenin manufacturing process has led to serious environmental contamination and wastewater. Clean processes are needed that can alternate the diosgenin production. The β-glucosidase FBG1, cloned from Fusarium sp.
Wancang Liu, Haibo Xiang, Haibo Xiang, Tao Zhang, Xu Pang, Jing Su, Hongyu Liu, Baiping Ma, Liyan Yu   +8 more
doaj   +1 more source

Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells [PDF]

Biochemical Journal, 1984
The aglycon form of the steroidal sapogenin furost −5-ene-3 beta, 22,26-triol, 3 beta- chacotrioside 26 beta-D-glucopyranoside was isolated from cell suspension cultures of Dioscorea deltoidea and its molecular structure was determined by mass spectrometry and 1H and 13C n.m.r. spectroscopy.
B, Tal, I, Tamir, J S, Rokem, I, Goldberg   +3 more
openaire   +2 more sources

Impact of ploidy change on secondary metabolites and photochemical efficiency in Solanum bulbocastanum Dun. [PDF]

, 2013
Plants are well known for producing a wide diversity of natural compounds and several strategies have been proposed to enhance their production. Among them, somatic chromosome doubling may represent an effective and inexpensive method.
Aversano R, Carputo D, Caruso I, Dal Piaz F, De Tommasi N, Malafronte M, Scarano MT, Zottelec CW   +7 more
core   +3 more sources