Results 11 to 20 of about 1,074 (118)

Diosgenin producing Bacillus sp. strain IRMC27M2 as a genome-mined weapon against multidrug-resistant Candidozyma (Candida) auris [PDF]

Computational and Structural Biotechnology Journal
Candidozyma auris (Candida auris) is an emerging multidrug-resistant (MDR) fungal pathogen prioritised by the World Health Organisation that poses a significant global health threat due to high mortality. Discovering novel antifungal drugs is crucial for
Rahaf Alquwaie, Noor B. Almandil, Reem AlJindan, Nehal Mahmoud, Sarah Almofty, Dana Almohazey, Hoor Hashim Alqudihi, Sarah Hunachagi, Tharmathass Stalin Dhas, P. Sowmiya, Sayed AbdulAzeez, J. Francis Borgio   +11 more
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De Novo Transcriptome Sequencing in Trigonella foenum-graecum L. to Identify Genes Involved in the Biosynthesis of Diosgenin

The Plant Genome, 2013
T L. (fenugreek) is a viable alternative for production of diosgenin because of its shorter growing cycle, lower production costs, and consistent yield and quality.
Kanak Vaidya, Arpita Ghosh, Vinay Kumar, Spandan Chaudhary, Navin Srivastava, Kalpesh Katudia, Tanushree Tiwari, Surendra K. Chikara   +7 more
doaj   +2 more sources

Integrated MALDI-MSI and UHPLC-OE-MS for Spatial Visualization and Biosynthetic Pathway Elucidation of Bioactive Metabolites in Lilium lancifolium Thunb. [PDF]

Molecules
Lilium lancifolium Thunb. is an important economic crop widely cultivated and traded across Asia and has significant pharmacological activity. Despite decades of research on their chemical composition, the spatial distribution patterns of characteristic ...
Qibo Deng, Zhihui Wang, Jiajia Ji, Minsi Xie, Qiaozhen Tong, Kunlai Sun, Qinghua Peng, Zhiying Yuan   +7 more
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Advances in fenugreek breeding: novel genetic and omic approaches [PDF]

Frontiers in Plant Science
Fenugreek (Trigonella foenum-graecum L.) has long been valued for its diverse applications in culinary, medicinal, and cultural traditions across the globe.
Solanki Bal, Amit Baran Sharangi, Mohd Saeed, Ali Alkhathami, Samra Siddiqui, Nadiyah M. Alabdallah   +5 more
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Systemic role of melatonin in enhancing temperature stress tolerance in fenugreek: coordination of antioxidant defense, hormonal regulation, energy status, sulfur metabolism, and diosgenin pathway genes [PDF]

BMC Plant Biology
Background Temperature stresses, encompassing heat and cold, significantly hinder the growth and productivity of fenugreek. Melatonin, known for its antioxidant and signaling properties, enhances plant stress tolerance, yet its specific role and mode of ...
Shahrokh Gharanjik, Amin Ebrahimi, Liela Rezaei Somee, Zeinab Chaghakaboodi, Hadi Alipour   +4 more
doaj   +2 more sources

Identification of genetic variants controlling diosgenin content in Dioscorea zingiberensis tuber by genome-wide association study [PDF]

BMC Plant Biology
Background Diosgenin is an important steroidal precursor renowned for its diverse medicinal uses. It is predominantly sourced from Dioscorea species, particularly Dioscorea zingiberensis.
Shi xian Sun, Yanmei Li, Lu Jia, Shili Ye, Yunpeng Luan   +4 more
doaj   +2 more sources

Titanium dioxide -mediated regulation of enzymatic and non-enzymatic antioxidants, pigments, and diosgenin content promotes cold stress tolerance in Trigonella foenum-graecum L. [PDF]

Scientific Reports
Abiotic stresses, notably cold stress, significantly influence various aspects of plant development and reproduction. Various approaches have been proposed to counteract the adverse impacts of cold stress on plant productivity.
Mohamad Javad Babaei, Amin Ebrahimi, Parviz Heidari, Elham Azadvari, Shahrokh Gharanjik, Zeinab Chaghakaboodi   +5 more
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Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek [PDF]

BMC Genomics
Medicinal plants are rich sources for treating various diseases due their bioactive secondary metabolites. Fenugreek (Trigonella foenum-graecum) is one of the medicinal plants traditionally used in human nutrition and medicine which contains an active ...
Sara Lamei Javan, Arman Beyraghdar Kashkooli, AbdolAli Shojaeiyan, Sina Majidian   +3 more
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Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum. [PDF]

Plant Biotechnol J
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Lim J, Kim K, Heo J, Seo SM, Choung S, Kim H, Choi Y, Park K, Yun H, Kim D, Lee ES, Lee J, Warsadiharja SM, Lee SB, Han S, Park SJ, Kim SG.   +16 more
europepmc   +2 more sources

The origin and evolution of the diosgenin biosynthetic pathway in yam

Plant Communications, 2021
Diosgenin, mainly produced by Dioscorea species, is a traditional precursor of most hormonal drugs in the pharmaceutical industry. The mechanisms that underlie the origin and evolution of diosgenin biosynthesis in plants remain unclear.
Jian Cheng, Jing Chen, Xiaonan Liu, Xiangchen Li, Weixiong Zhang, Zhubo Dai, Lina Lu, Xiang Zhou, Jing Cai, Xueli Zhang, Huifeng Jiang, Yanhe Ma   +11 more
doaj   +1 more source