Results 101 to 110 of about 2,018 (130)
Brain DisordersInhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation can provide normalization of neurochemical homeostasis and neurotrophic support in the pathogenesis of psychiatric disorders with complex symptoms such as ...
Benneth Ben-Azu +10 more
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Production of diosgenin by hairy root cultures of Trigonella foenum-graecum L [PDF]
, 2018 Hairy root cultures ofTrigonella foenum-graecum L. were established withAgrobacterium rhizogenes strain A4. The hairy roots produce diosgenin, an important spirostanol for the semi-synthesis of steroid hormones.
Merkli, A. +2 more
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Estimation of Diosgenin by HPLC in a Dioscorea zingiberensis Collection from Different Local Markets in Middle and South Iraq [PDF]
Diosgenin, a steroidal sapogenin, is found in significant quantities in some plant species, such as Dioscorea alata, Smilax China, and Trigonella foenum graecum.
jebor, Mohammed Abdullah +2 more
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Analysis of diosgenin and phenol compounds in Tribulus terrestris L.
, 2019 Caltrop (Tribulus terrestris L.) is a weed plant widely growing in warm climate. The crude caltrop has multidirectional pharmacological action favorable for the development of drug preparations.
Burda, Nadiia Ye. +7 more
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Journal of Medicinal Plants, 2010 Fenugreek (Trigonella foenum-graecum L.) has a long and respected history of medicinal uses in Middle East and Persian medicine. The hypocholesterolaemic and hypoglycaemic effects of fenugreek were attributed to its major steroidal sapogenin, diosgenin ...
A Mehrafarin +5 more
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Natural Product CommunicationsThe present study is aimed to explore the therapeutic attributes of diosgenin against atherosclerosis and associated health disorder. Side effects associated with synthetic drugs for the treatment and management of diseases worldwide have necessitated ...
Rizwan ur-Rehman +5 more
doaj +1 more source
, 2007 Diosgenin為山藥中具生理效應的主要成分，結構與固醇類荷爾蒙相似，所以廣被製藥業拿來作為合成荷爾蒙(如黃體素、睪固酮等)或類固醇製劑的原料。現已有文獻指出diosgenin可顯著減少因卵巢切除而造成骨質疏鬆老鼠之骨質流失。骨質代謝包括骨合成（bone formation）與骨吸收（bone resorption）。調控骨再塑（bone remodling）的二個主要細胞為：造骨細胞(osteoblasts) 及破骨細胞(osteoclasts)，造骨細胞主要負責骨骼的製造 ...
陳瑋芳, Chen, Wei-Fang
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Discover ChemistryBackground Diosgenin is a steroidal saponin of Dioscorea and Trigonella species, which has been gaining a lot of interest due to its health-promoting action.
Tayyaba Rao +6 more
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Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum
Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of ...
Park, Soon Ju +16 more
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, 2008 Fatty acid synthase (FAS) expression is markedly elevated in HER2- overexpressing breast cancer cells. In this study, diosgenin, a plant- derived steroid, was found to be effective in suppressing FAS expression in HER2- overexpressing breast cancer cells.
江俊德;魏宗德;林仁混 +1 more
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