Results 161 to 170 of about 4,688 (209)

Phytochemical Profiling and Molecular Insights of <i>Centaurea lycaonica</i>: Apoptosis Induction via the Intrinsic Pathway in Endometrial Cancer Cells. [PDF]

Pharmaceuticals (Basel)
Karaboğa Arslan AK, Korubaşı R, Paşayeva L, Bozkurt NM, Tugay O.   +4 more
europepmc   +1 more source

Dynamic Chemical Profiling of <i>Lonicera japonica</i> Flos During the Maceration and Decoction Processes Integrating UPLC-MS and Molecular Networking. [PDF]

Foods
Ding H, Sun C, Kang C, Liu Y, Wang X, Li L.   +5 more
europepmc   +1 more source

Integrated multiomics profiling elucidates the spatiotemporal metabolic dynamics and regulatory networks of the bioactive components of <i>Trichosanthes kirilowii</i>. [PDF]

Front Plant Sci
Gao H, Li X, Wang C, Li Y, Liu T, Chang N, Xu Y, Wang Y, Ren Y, Zhou G, Gao W, Zeng Y, Zhao H, Li H.   +13 more
europepmc   +1 more source

Screening the Active Phytochemicals From <i>Eclipta prostrata</i> and Unraveling Their Molecular Insight Into Human Malignancies. [PDF]

Cancer Innov
Hossain MS, Khatun S, Mia MM, Zohora F, Sarker MR, Tanjida Islam KM, Sayeed MA, Mou MA, Hamidu S, Hamidu F, Wasaf Hasan AM, Mumtaj S, Hossain MK, Sohel M.   +13 more
europepmc   +1 more source

RETRACTION: Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decreasing Oxidative Stress and Myocardial Apoptosis. [PDF]

Clin Exp Pharmacol Physiol
europepmc   +1 more source

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Diosmetin Induces Apoptosis of Acute Myeloid Leukemia Cells

Molecular Pharmaceutics, 2018
Acute myeloid leukemia is an aggressive disease with limited and nonselective therapeutic options. This study explored the bioactivity and cell death inducing mechanism of diosmetin, a novel compound identified in a nutraceutical screen to impart selective anti-AML activity.
Alessia Roma, Paul A Spagnuolo
exaly   +3 more sources

Mechanism underlying the vasodilation induced by diosmetin in porcine coronary artery

European Journal of Pharmacology, 2020
Diosmetin is a flavonoid present naturally in citrus fruit. Plants containing diosmetin have been reported to have anti-hypertensive and vasorelaxant effects. Therefore, experiments were carried out to study the effects of diosmetin in segments of the porcine coronary artery (PCA).
Taseer Ahmad, Abdul Jabbar Shah, Taous Khan   +2 more
exaly   +3 more sources

Probing the Binding of the Flavonoid Diosmetin to Human Serum Albumin by Multispectroscopic Techniques

Journal of Agricultural and Food Chemistry, 2012
The binding mechanism of molecular interaction between diosmetin and human serum albumin (HSA) in a pH 7.4 phosphate buffer was studied using atomic force microscopy (AFM) and various spectroscopic techniques including fluorescence, resonance light scattering (RLS), UV-vis absorption, circular dichroism (CD), and Fourier transform infrared (FT-IR ...
Guowen Zhang, Junhui Pan
exaly   +3 more sources

Inhibition of Cytochrome P450 2C8-mediated Drug Metabolism by the Flavonoid Diosmetin

Drug Metabolism and Pharmacokinetics, 2011
The aim of this study was to assess the effects of diosmetin and hesperetin, two flavonoids present in various medicinal products, on CYP2C8 activity of human liver microsomes using paclitaxel oxidation to 6α-hydroxy-paclitaxel as a probe reaction. Diosmetin and hesperetin inhibited 6α-hydroxy-paclitaxel production in a concentration-dependent manner ...
Luigi Quintieri, Pietro Palatini, Stefano Moro   +2 more
exaly   +3 more sources