Results 61 to 70 of about 4,688 (209)

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Diosmetin ameliorates osteoarthritic inflammation in vivo and ECM macromolecules degradation in interleukin-1β-stimulated murine chondrocytes through the Nrf2/NF-κB pathway

Folia Histochemica et Cytobiologica
INTRODUCTION: Osteoarthritis (OA) is a prevailing degenerative disease in elderly population and can lead to severe joint dysfunction. Studies have revealed various pharmacological activities of diosmetin, including the anti-OA efficacy.
Liang Qian, Chuang Li, Hong Liu, Hui Zhou, Tao Tan   +4 more
doaj   +1 more source

Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]

, 2014
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes, Antonis Vlassopoulos, Bhagwat, El-Salem, Emilie Combet, Hao, Hodge, Khaw, Koenig, Maillard, Malickova, Michael E. J. Lean, Monnier, Nicholl, Rothwell, Schmidt, Sell, Vlassara   +17 more
core   +3 more sources

Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Amal Elrherabi, Oussama Khibech, Mohamed Bouhrim, Abdelouahid Laftouhi, Abdelaaty A. Shahat, Abdullah R. Alanzi, Rashed N. Herqash, Joe Miantezila Basilua, Mohamed Bnouham   +8 more
wiley   +1 more source

Inhibition of TGF-β Signaling in Gliomas by the Flavonoid Diosmetin Isolated from Dracocephalum peregrinum L.

Molecules, 2020
Background: Dracocephalum peregrinum L., a traditional Kazakh medicine, has good expectorant, anti-cough, and to some degree, anti-asthmatic effects. Diosmetin (3′,5,7-trihydroxy-4′-methoxyflavone), a natural flavonoid found in traditional ...
Yuli Yan, Xingyu Liu, Jie Gao, Yin Wu, Yuxin Li   +4 more
doaj   +1 more source

α-Amylase inhibitors : a review of raw material and isolated compounds from plant source [PDF]

, 2012
Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes and obesity, as well as, dental caries and periodontal diseases ...
Batista, Pérola de Oliveira Magalhães Dias, Sales, Paloma Michelle de, Silveira, Dâmaris, Simeoni, Luiz Alberto, Souza, Paula Monteiro de   +4 more
core   +2 more sources

Effects of Juice Processing on Anti-inflammatory Flavonoids in Plant Foods [PDF]

, 2009
Apigenin glycosides are abundant in parsley, celery, and chamomile tea and possess unique anti-inflammatory properties in vitro. Apigenin O-glycosides have been evaluated in foods by hydrolysis and comparison to aglycone standards, but intact O- and C ...
Hostetler, Greg
core  

Flavonoid Inhibition of Bacillus licheniformis LP‐8 Lipase: In Vitro and In Silico Insights Into Anti‐Obesity Potential

ChemistryOpen, Volume 15, Issue 5, May 2026.
Bacillus licheniformis LP‐8, isolated from hot spring, produced lipase using waste frying oil. Flavonoids inhibited enzyme activity, confirmed by reduced activity assays. Molecular docking revealed hydrogen‐bond interactions within the lipase active site.
Songul Bayrak, Mehmet Akif Omeroglu, Halil Senol   +2 more
wiley   +1 more source

Formulation and characterization of an apigenin-phospholipid phytosome (APLC) for improved solubility, in vivo bioavailability, and antioxidant potential [PDF]

, 2016
The apigenin-phospholipid phytosome (APLC) was developed to improve the aqueous solubility, dissolution, in vivo bioavailability, and antioxidant activity of apigenin.
Anand, Sridhar, Dave, Vivek S., Fegade, Harshal, Patin, Arun T., Pethe, Anil M., Telange, Darshan R.   +5 more
core   +2 more sources

Integrative Network Pharmacology, Molecular Docking, and In Vitro Insights Into the Mechanism of Finger Citron for Non‐Alcoholic Fatty Liver Disease

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
An integrative strategy combining network pharmacology, molecular docking, and in vitro cellular experiments was employed to elucidate the anti‐NAFLD mechanism of FC. A total of 62 bioactive compounds and 306 common target genes were identified, followed by PPI, GO, and KEGG analyses to screen key targets and pathways.
Qingpeng Li, Huilong Sun, Xiaoling Chen, Chunyang Chen, Yongsheng Chen, Hui He, Fan Yang, Dan Wang, Lin Zhou   +8 more
wiley   +1 more source