Results 61 to 70 of about 2,828 (161)

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

ChemistryOpen, Volume 15, Issue 4, April 2026.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni, Aziz Drioiche, Fadoua El Makhoukhi, Omkulthom Al kamaly, Hannou Zerkani, Smail Amalich, Imane Tagnaout, Mohamed Radi, Yahya Cherrah, Touriya Zair, Katim Alaoui   +10 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Changes of Phenolic Profiles, Bioaccessibility, and Antioxidant Performance of Areca catechu L. Extracts During In Vitro Digestion

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This diagram illustrates the dynamic changes in phenolic content, bioaccessibility, antioxidant activity, and phenolic profiles of areca nut extracts from different parts during in vitro digestion, highlighting their functional food potential. ABSTRACT Areca nut (Areca catechu L.), an economically vital tropical fruit in China, generates substantial ...
Wenting Dai, Xiaoning Kang, Jiahui Dai, Shiping Wang, Jianbang Ji   +4 more
wiley   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

The FEBS Journal, Volume 293, Issue 5, Page 1386-1399, March 2026.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima, Sayako Shimomura, Mayuka Wakabayashi, Wei Qi Loh, Harumi Ando, Haruka Sei, Hiroyuki Hattori, Didik Huswo Utomo, Masaki Kita, Asuka Inoue, Koji Uchida, Takahiro Shibata   +11 more
wiley   +1 more source

Potential Therapeutic Anti-Inflammatory and Immunomodulatory Effects of Dihydroflavones, Flavones, and Flavonols

Molecules, 2020
Systemic inflammation, circulating immune cell activation, and endothelial cell damage play a critical role in vascular pathogenesis. Flavonoids have shown anti-inflammatory effects.
Cristina Zaragozá, Lucinda Villaescusa, Jorge Monserrat, Francisco Zaragozá, Melchor Álvarez-Mon   +4 more
doaj   +1 more source

Tailored biosynthesis of diosmin through reconstitution of the flavonoid pathway in Nicotiana benthamiana

Frontiers in Plant Science
The flavonoid diosmin (diosmetin 7-O-rutinoside) is used as a therapeutic agent for disorders of the blood vessels such as hemorrhoids and varicose veins. Diosmin is commercially produced using semi-synthetic methods involving the oxidation of hesperidin,
Hyo Lee, Sangkyu Park, Saet Buyl Lee, Jaeeun Song, Tae-Hwan Kim, Beom-Gi Kim   +5 more
doaj   +1 more source

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice

Molecules, 2019
Colon cancer is the third most common type of cancer in the world. Diosmetin (Dis), a natural O-methylated flavone, has been reported to have anti-cancer effects against different types of cancer.
Sanaz Koosha, Zahurin Mohamed, Ajantha Sinniah, Mohammed A. Alshawsh   +3 more
doaj   +1 more source

Dioscin attenuates lupus nephritis in NZB/W F1 mice by decreasing NF-κB activation and NLRP3 inflammasome

Folia Histochemica et Cytobiologica
INTRODUCTION: Dioscin, a natural steroid saponin, has anticancer, anti-inflammatory, anti-hyperlipidemic, and glycemic capabilities. This study focused on dioscin roles and its related mechanisms in experimental lupus nephritis.
Yaling Xu, Han Li
doaj   +1 more source

Diosmin and its aglycone form Diosmetin as potential therapeutics for cardiovascular diseases

Journal of Functional Foods
Cardiovascular disease (CVD) is the principal etiology of death worldwide. Flavonoids are phytochemicals existing in vegetables, tea, fruits, cocoa, and wines that have been linked to positive pharmacological properties, counting antithrombotic ...
Sara Asadi, Parisa Zare Mehrjerdi, Soroush Fotouhi, Vahid Reza Askari, Vafa Baradaran Rahimi   +4 more
doaj   +1 more source

Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers

Molecules, 2018
Diosmin is a flavonoid commonly found in citrus fruits, largely used as adjuvant treatment for circulatory disorders, including chronic venous insufficiency (CVI) and hemorrhoids.
Rosario Russo, Divya Chandradhara, Nunziatina De Tommasi   +2 more
doaj   +1 more source