Results 41 to 50 of about 4,688 (209)
Defining key structural determinants for the pro-osteogenic activity of flavonoids [PDF]
, 2015 Epidemiological studies suggest that fruits and vegetables may play a role in promoting bone growth and preventing age-related bone loss, attributable, at least in part, to phytochemicals such as flavonoids stimulating osteoblastogenesis.
Bicknell, Katrina A. +5 more
core +2 more sources
Effect of diosmetin on airway remodeling in a murine model of chronic asthma [PDF]
Acta Biochimica et Biophysica Sinica, 2015 Bronchial asthma, one of the most common allergic diseases, is characterized by airway hyperresponsiveness (AHR), inflammation, and remodeling. The anti-oxidant flavone aglycone diosmetin ameliorates the inflammation in pancreatitis, but little is known about its impact on asthma.
Ai, Ge +7 more
openaire +2 more sources
Human Gut Microbial Degradation of Flavonoids: Structure−Function Relationships [PDF]
, 2005 The relationship between chemical structure and gut microbial degradation rates of 14 flavonoids, flavone, apigenin, chrysin, naringenin, kaempferol, genistein, daidzein, daidzin, puerarin, 7,4‘-dihydroxyflavone, 6,4‘-dihydroxyflavone, 5,4 ...
Hendrich, Suzanne +4 more
core +3 more sources
Plants, 2023 Chronic venous disease (CVD) is an often underestimated inflammatory pathological condition that can have a serious impact on quality of life. Many therapies have been proposed to deal with CVD, but unfortunately the symptoms recur with increasing ...
Raffaella Nocera +9 more
doaj +1 more source
PLoS ONE, 2016 This study aimed to determine the reaction kinetics of the regioselective glucuronidation of diosmetin and chrysoeriol, two important methylated metabolites of luteolin, by human liver microsomes (HLMs) and uridine-5'-diphosphate glucuronosyltransferase (
Xuejun Zeng +10 more
doaj +1 more source
Molecules, 2022 Diosmin is widely used as a venoactive drug in the pharmacological treatment of chronic venous disorders. It exerts a strong protective effect on blood vessels via an increase in the elasticity of vessel walls and reduces the permeability of capillary ...
Marcin Feldo +4 more
doaj +1 more source
Kaohsiung Journal of Medical Sciences, 2022 Inhibition of hypoxia‐induced cardiomyocyte apoptosis is considered as an important treatment method for ischemic heart diseases, but related drugs are still insufficient. The present study aims to explore the protective function and mechanism of the key
Wen‐Shuai He +4 more
doaj +1 more source
Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer [PDF]
Cell Cycle, 2020 Radiotherapy is an essential treatment for endometrial cancer (EC), especially in advanced, metastatic, and recurrent cases. Combining radiotherapy, which mainly causes DNA double-strand breaks (DSBs), with small molecules targeting aberrantly activated homologous recombination (HR) repair pathways holds great potential for treating ECs in advanced ...
Zhiyi, Hu +9 more
openaire +2 more sources
Study of C- and O-glycosylflavones in sugarcane extracts using liquid chromatography: exact mass measurement mass spectrometry [PDF]
, 2008 The flavonoids present in sugarcane (Saccharum officinarum) extracts were analyzed by liquid chromatography - mass spectrometry (LC-MS), and a study of the fragmentation patterns of selected flavonoids was conducted using orthogonal acceleration time-of ...
COLOMBO, Renata +2 more
core +1 more source
Synthetic flavonoids as novel modulators of platelet function and thrombosis [PDF]
, 2019 Cardiovascular diseases represent a major cause of mortality and morbidity in the world and thrombotic conditions such as heart attacks and strokes are caused by unwarranted activation of platelets and subsequent formation of blood clots (thrombi) within
Dina A. I. Albadawi +7 more
core +1 more source