Flavones from Erythrina falcata are modulators of fear memory [PDF]
Background: Flavonoids, which have been identified in a variety of plants, have been demonstrated to elicit beneficial effects on memory. Some studies have reported that flavonoids derived from Erythrina plants can provide such beneficial effects on ...
Cavalheiro, Alberto J. +6 more
core +1 more source
IntroductionApolipoprotein (apo) E4, being a major genetic risk factor for Alzheimer’s disease (AD), is actively involved in the proteolytic processing of amyloid precursor protein (APP) to amyloid β (Aβ) peptide, the principle constituent of amyloid ...
Viralkumar Davra, Kenza E. Benzeroual
doaj +1 more source
Direct Identification and Quantification of Flavonoids and Their Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry. [PDF]
ABSTRACT Rationale Flavonoids are phenolic compounds with many health‐benefiting properties. However, differentiating different types of flavonoids and their isomers is challenging due to their highly similar structures of various subtypes and different numbers and sites of substituents.
Wang Y, Xu L, Gu T, Li H, Chen DDY.
europepmc +2 more sources
Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing +3 more
core +1 more source
Physicochemical Properties of Diosmetin and Lecithin Complex
Purpose: To improve the hydrophobicity of diosmetin, the complex of diosmetin and lecithin was prepared and its physicochemical properties were characterized in this study.Methods: The complex of diosmetin and lecithin was prepared by solvent method. The physicochemical properties of the complex were investigated by ultraviolet-visible spectrometry(UV ...
Brad, Korbanjhon, Chen, Chungang
openaire +3 more sources
Flavonoid diosmetin increases ATP levels in kidney cells and relieves ATP depleting effect of ochratoxin A [PDF]
Diosmetin (DIOS) is a flavone aglycone commonly occurring in citrus species and olive leaves, in addition it is one of the active ingredients of some medications.
Antus, Csenge +8 more
core +1 more source
Diosmetin Exerts Synergistic Effects in Combination with 5-Fluorouracil in Colorectal Cancer Cells
5-Fluorouracil (5-FU) is a chemotherapeutic medication commonly used to treat colorectal cancer (CRC); however, the drug-associated adverse effects and toxicity have greatly affected its clinical use.
Sareh Kamran +3 more
doaj +1 more source
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
core +1 more source
Objective To investigate the effect of diosmetin on the proliferation, apoptosis and migration of colorectal cancer cells, and further to analyze whether its mechanism is related to the regulation of STX17-AS1/miR-383-5p axis.
WU Yuan, LIU Jiyu, ZHANG Qin
doaj +1 more source
HPLC microfractionation of flavones and antioxidant (radical scavenging) activity of Saccharum officinarum L. [PDF]
The antioxidant activity of sugarcane (Saccharum officinarum L.) juice towards DPPH reagent was determined (EC50) and the main compounds with radical scavenging activity in juice and leaves extracts were identified by HPLC-UV/PAD analysis combined with ...
COLOMBO, Renata +3 more
core +1 more source

