Results 171 to 180 of about 4,892 (216)
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The effect of diosmin against lead exposure in rats‡
Naunyn-Schmiedeberg's Archives of Pharmacology, 2019In this study, the effect of diosmin against the adverse effects of lead exposure in rats was investigated. Wistar Albino race 40 male rats weighing 150-200 g 2-3 months were used. A total of 4 groups were assigned, one of which was control and the other 3 were trial groups.
Mehmet Bozdağ, Gökhan Eraslan
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Diosmin-containing phlebotropic drugs in varicose eczema
Angiology and vascular surgery, 2019The purpose of the study was to examine the effect of diosmine-based phlebotropic drugs on dynamics of regress of varicose eczema in patients with chronic venous diseases, to compare their objective complaints and subjective symptoms before and after treatment, to determine the time of improvement.The study enrolled a total of 80 patients presenting ...
D V, Rodnyansky, A A, Fokin
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Effects of Micronization on Digestive Absorption of Diosmin
Phlebology: The Journal of Venous Disease, 1994Objective: To investigate the effect of diosmin particle size on the rate and extent of absorption and excretion of total radioactivity, following oral administration of micronized and non-micronized [14C]-diosmin to New Zealand White rabbits. Design: This study was conducted in a 2 x 12 cross-over design at a uniform target dose level of 10 mg/kg, and
A. M. Johnston, H. J. Paul, C. G. Young
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A pharmacokinetic study of 3H-diosmine.
Arzneimittel-Forschung, 1977A pharmacokinetic study of 3H-labelled 7-rhamnoglycoside of 5,7,3'-trihydroxy-4'-methoxyflavone (3H-diosmine) administered both i.v. and orally, shows the great ease with which it is absorbed in digestion. A very sharp difference in elimination between the two modes of treatment must be associated with a difference in metabolism.
J, Oustrin, M J, Fauran, L, Commanay
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[Studies on pharmacokinetics of diosmin in rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008To establish a HPLC method for the determination of diosmin in Rats plasma and to study the pharmacokinetics of diosmin in Rats.Rats were given diosmin with 3 doses as 225, 325, 425 mg x kg(-1). Blood samples were collected at different times after oral administration. The plasma concentration of diosmin was determined by HPLC, and the pharmacokinetics
Ying-Li, Ma, Chao, Ma
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Diosmin: A potential natural drug
Global Journal of Basic ScienceDiosmin is of potential interest for its possible role in human health. Diosmin is a flavone glycoside that is a member of the class of flavonoids, which are secondary metabolites found in large quantities in plants and vegetables. Diosmin is specifically the glycoside of the aglycon diosmetin (3′, 5, 7-trihydroxy-4′-methoxyflavone), which is found ...
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