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The Aryl Hydrocarbon Receptor in Neurotoxicity: An Intermediator Between Dioxins and Neurons in the Brain [PDF]

Toxics
Industrial development has increased environmental dioxin concentrations, sparking concern about human health impacts. Examining dioxin neurotoxicity has highlighted associations with cognitive impairment and behavioral abnormality.
Eiki Kimura
doaj   +2 more sources

Associations Between Perinatal Dioxin Exposure and Circadian Clock Gene mRNA Expression in Children in Dioxin-Contaminated Areas of Vietnam [PDF]

Toxics
We investigated the impact of perinatal dioxin exposure (indicated by dioxin levels in maternal breast milk) on clock gene mRNA expression in buccal cells of 9-year-old children from the Da Nang birth cohort in Vietnam using reverse transcription ...
Thao Ngoc Pham, Hoa Thi Vu, Takafumi Tasaki, Tai Pham-The, Nghi Ngoc Tran, Muneko Nishijo, Tien Viet Tran, Hai Anh Tran, Tomoya Takiguchi, Yoshikazu Nishino   +9 more
doaj   +2 more sources

Monitoring of Polycyclic Aromatic Hydrocarbon Levels in Mussels (Mytilus galloprovincialis) from Aquaculture Farms in Central Macedonia Region, Greece, Using Gas Chromatography–Tandem Mass Spectrometry Method

Molecules, 2021
A new sensitive and selective gas chromatography tandem mass spectrometry (GC-MS/MS) method was developed for the analysis of 26 polycyclic aromatic hydrocarbons (PAHs), including 16 Environmental Protection Agency (EPA) and 15 + 1 European Union (EU ...
Constantina Grigoriou, Danae Costopoulou, Irene Vassiliadou, Dimitrios Chrysafidis, Vassilios Tzamtzis, Evangelos Bakeas, Leondios Leondiadis   +6 more
doaj   +1 more source

Alterations in Regional Brain Regional Volume Associated with Dioxin Exposure in Men Living in the Most Dioxin-Contaminated Area in Vietnam: Magnetic Resonance Imaging (MRI) Analysis Using Voxel-Based Morphometry (VBM)

Toxics, 2021
To clarify the influence of dioxin exposure on brain morphometry, the present study investigated associations between dioxin exposure at high levels and brain structural irregularities in 32 Vietnamese men.
Hoa Thi Vu, Thao Ngoc Pham, Takashi Yokawa, Muneko Nishijo, Tai Pham The, Quyet Do, Yoshikazu Nishino, Hisao Nishijo   +7 more
doaj   +1 more source

Dioxins and dioxin-like compounds in meat and meat products

Теория и практика переработки мяса, 2022
Dioxin and dioxin-like compounds are persistent organic pollutants that received considerable attention in recent years due to their high potential toxicity, wide distribution and extreme stability.
E. Aoudeh, E. Oz, M. R. Khan, F. Oz
doaj   +1 more source

Systematic review and meta-analysis of cancer risks in relation to environmental waste incinerator emissions: a meta-analysis of case-control and cohort studies [PDF]

Epidemiology and Health, 2022
OBJECTIVES Various toxic substances can be generated from incinerators, exposing nearby residents, and epidemiological studies have shown wide variations in risk estimates for cancer risk in populations living close to incinerators. METHODS Following the
Kiook Baek, Jong-Tae Park, Kyeongmin Kwak   +2 more
doaj   +1 more source

The footprint of dioxins in globally traded pork meat

iScience, 2021
Summary: The bioaccumulation of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), known as dioxins, in fatty meat is one of primary pathways of entry into the human body, but levels of human exposure to dioxins in fatty meat subject to global trade are
Kaijie Chen, Tao Huang, Xiaodong Zhang, Xinrui Liu, Yufei Huang, Linfei Wang, Yuan Zhao, Hong Gao, Shu Tao, Junfeng Liu, Xiaohu Jian, Alexey Gusev, Jianmin Ma   +12 more
doaj   +1 more source

PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor. [PDF]

PLoS ONE, 2012
Dioxins and dioxin-like compounds encompass a group of structurally related heterocyclic compounds that bind to and activate the aryl hydrocarbon receptor (AhR).
Wenshuo Zhang, Robert M Sargis, Paul A Volden, Christopher M Carmean, Xiao J Sun, Matthew J Brady   +5 more
doaj   +1 more source

Dioxin toxicity in vivo results from an increase in the dioxin-independent transcriptional activity of the aryl hydrocarbon receptor.

PLoS ONE, 2010
The Aryl hydrocarbon receptor (Ahr) is the nuclear receptor mediating the toxicity of dioxins--widespread and persistent pollutants whose toxic effects include tumor promotion, teratogenesis, wasting syndrome and chloracne.
Miguel Angel Céspedes, Maximo Ibo Galindo, Juan Pablo Couso   +2 more
doaj   +1 more source

Serum metabolic changes associated with dioxin exposure in a Chinese male cohort

Environment International, 2020
Dioxins, a group of persistent organic pollutants, have been proved to correlate with ranges of diseases by activating the aryl hydrocarbon receptor (AhR).
Yanshan Liang, Zhi Tang, Yousheng Jiang, Chunyan Ai, Jinling Peng, Yuan Liu, Jinru Chen, Jianqing Zhang, Zongwei Cai   +8 more
doaj   +1 more source