Results 41 to 50 of about 55,716 (280)

Acute deletion of TET enzymes results in aneuploidy in mouse embryonic stem cells through decreased expression of Khdc3

Nature Communications, 2022
Inducible disruption of TET dioxygenases in mouse embryonic stem cells results in chromosome mis-segregation and aneuploidies, due to Khdc3 downregulation suggesting a role for TET enzymes and DNA methylation patterns in maintaining genome stability.
Romain O. Georges, Hugo Sepulveda, J. Carlos Angel, Eric Johnson, Susan Palomino, Roberta B. Nowak, Arshad Desai, Isaac F. López-Moyado, Anjana Rao   +8 more
doaj   +1 more source

Genome-wide identification and in-silico expression analysis of carotenoid cleavage oxygenases gene family in Oryza sativa (rice) in response to abiotic stress

Frontiers in Plant Science, 2023
Rice constitutes a foundational cereal and plays a vital role in the culinary sector. However, the detriments of abiotic stress on rice quality and productivity are noteworthy. Carotenoid cleavage oxygenases (CCO) hold vital importance as they enable the
Muhammad Zeshan Haider, Adnan Sami, Muhammad Shafiq, Waheed Anwar, Sajid Ali, Qurban Ali, Sher Muhammad, Irfan Manzoor, Muhammad Adnan Shahid, Daoud Ali, Saud Alarifi   +10 more
doaj   +1 more source

Does abscisic acid affect strigolactone biosynthesis? [PDF]

, 2010
Strigolactones are considered a novel class of plant hormones that, in addition to their endogenous signalling function, are exuded into the rhizosphere acting as a signal to stimulate hyphal branching of arbuscular mycorrhizal (AM) fungi and germination
Adie, Akiyama, Alder, Andrew J. Thompson, Anna K. Undas, Aroca, Auldridge, Bainbridge, Bethke, Booker, Booker, Bouwmeester, Bouwmeester, Burbidge, Carbone, Carolien Ruyter-Spira, Christmann, Cook, Cornish, Cutler, Davies, De Smet, Dunlap, Ejeta, Francel Verstappen, Fraser, Gomez-Roldan, Harrison, Harro Bouwmeester, Hernandez, Herrera-Medina, Jeschke, Jiang, Juan A. López-Ráez, Kahn, Kitahata, Li, Livak, López-Ráez, López-Ráez, López-Ráez, López-Ráez, Martin J. Sergeant, Matusova, Misson, Nitsch, Parry, Parry, Paszkowski, Patrick Mulder, Rani, Rock, Sagi, Saika, Schwartz, Schwartz, Schwartz, Sergeant, Simkin, Sorefan, Spinsanti, Strack, Sun, Tan, Tatsiana Charnikhova, Taylor, Taylor, Thompson, Thompson, Timothy D. H. Bugg, Umehara, Vogel, Wasaki, Wouter Kohlen, Yoneyama, Yoneyama, Zeevaart   +76 more
core   +4 more sources

Carotenoid Cleavage Dioxygenases: Identification, Expression, and Evolutionary Analysis of This Gene Family in Tobacco

International Journal of Molecular Sciences, 2019
Carotenoid cleavage dioxygenases (CCDs) selectively catalyze carotenoids, forming smaller apocarotenoids that are essential for the synthesis of apocarotenoid flavor, aroma volatiles, and phytohormone ABA/SLs, as well as responses to abiotic stresses ...
Qianqian Zhou, Qingchang Li, Peng Li, Song-tao Zhang, Che Liu, Jingjing Jin, Peijian Cao, Yongxia Yang   +7 more
semanticscholar   +1 more source

Hemoglobin: A Nitric-Oxide Dioxygenase [PDF]

Scientifica, 2012
Members of the hemoglobin superfamily efficiently catalyze nitric-oxide dioxygenation, and when paired with native electron donors, function as NO dioxygenases (NODs). Indeed, the NOD function has emerged as a more common and ancient function than the well-known role in O2transport-storage.
openaire   +4 more sources

Sufficiency of hypoxia-inducible 2-oxoglutarate dioxygenases to block chemical oxidative stress-induced differentiation of human embryonic stem cells

Stem Cell Research, 2019
Hypoxia benefits undifferentiated pluripotent stem cell renewal, and 2-oxoglutarate (2OG) dioxygenases have been implicated in pluripotent stem cell induction and renewal.
Eirini Koutsouraki, Steve Pells, Paul A. De Sousa   +2 more
doaj   +1 more source

Oxygen concentration controls epigenetic effects in models of familial paraganglioma. [PDF]

PLoS ONE, 2015
Familial paraganglioma (PGL) is a rare neuroendocrine cancer associated with defects in the genes encoding the subunits of succinate dehydrogenase (SDH), a tricarboxylic acid (TCA) cycle enzyme.
Yeng F Her, Molly Nelson-Holte, Louis James Maher   +2 more
doaj   +1 more source

TET family dioxygenases and DNA demethylation in stem cells and cancers

Experimental &Molecular Medicine, 2017
The methylation of cytosine and subsequent oxidation constitutes a fundamental epigenetic modification in mammalian genomes, and its abnormalities are intimately coupled to various pathogenic processes including cancer development.
Jungeun An, A. Rao, M. Ko
semanticscholar   +1 more source

Enrichment and Identification of Askarel oil (PCB blend) degrading bacteria enriched from landfill sites in Edo State, Nigeria. [PDF]

, 2011
Microbial degradation following aerobic biodegradation is one of the means used by microorganisms for the removal of persistent organic pollutants from the soil. Bacterial species namely: Pseudomonas, Micrococcus Arthrobacter and Acinetobacter capable of
Nwinyi, Obinna
core   +1 more source

Redesign of a Dioxygenase in Morphine Biosynthesis

Chemistry & Biology, 2012
Opium poppy (Papaver somniferum) produces medicinally important benzylisoquinoline alkaloids, including the analgesics codeine and morphine, in the morphinan pathway. We aligned three dioxygenases that were recently discovered in P. somniferum and subsequently identified the nonconserved regions. Two of these enzymes, codeine O-demethylase (PsCODM) and
Weslee S. Glenn, Weslee S. Glenn, Sarah E. O'Connor, Sarah E. O'Connor, Weerawat Runguphan   +4 more
openaire   +5 more sources