Results 31 to 40 of about 25,696 (256)

Pathways to defense metabolites and evading fruit bitterness in genus Solanum evolved through 2-oxoglutarate-dependent dioxygenases

Nature Communications, 2019
The genus Solanum comprises three food crops (potato, tomato, and eggplant), which are consumed on daily basis worldwide and also producers of notorious anti-nutritional steroidal glycoalkaloids (SGAs). Hydroxylated SGAs (i.e.
P. Cárdenas, Prashant D. Sonawane, U. Heinig, A. Jozwiak, S. Panda, B. Abebie, Y. Kazachkova, M. Pliner, T. Unger, D. Wolf, Itai Ofner, Ester Vilaprinyó, S. Meir, Olga Davydov, A. Gal‐On, S. Burdman, A. Giri, D. Zamir, T. Scherf, J. Szymański, I. Rogachev, A. Aharoni   +21 more
semanticscholar   +1 more source

Genome-wide identification and in-silico expression analysis of carotenoid cleavage oxygenases gene family in Oryza sativa (rice) in response to abiotic stress

Frontiers in Plant Science, 2023
Rice constitutes a foundational cereal and plays a vital role in the culinary sector. However, the detriments of abiotic stress on rice quality and productivity are noteworthy. Carotenoid cleavage oxygenases (CCO) hold vital importance as they enable the
Muhammad Zeshan Haider, Adnan Sami, Muhammad Shafiq, Waheed Anwar, Sajid Ali, Qurban Ali, Sher Muhammad, Irfan Manzoor, Muhammad Adnan Shahid, Daoud Ali, Saud Alarifi   +10 more
doaj   +1 more source

Sufficiency of hypoxia-inducible 2-oxoglutarate dioxygenases to block chemical oxidative stress-induced differentiation of human embryonic stem cells

Stem Cell Research, 2019
Hypoxia benefits undifferentiated pluripotent stem cell renewal, and 2-oxoglutarate (2OG) dioxygenases have been implicated in pluripotent stem cell induction and renewal.
Eirini Koutsouraki, Steve Pells, Paul A. De Sousa   +2 more
doaj   +1 more source

Diversity of aromatic hydroxylating dioxygenase genes in mangrove microbiome and their biogeographic patterns across global sites

MicrobiologyOpen, 2017
Aromatic hydrocarbons (AH), such as polycyclic aromatic hydrocarbons, are compounds largely found in nature. Aromatic‐ring‐hydroxylating dioxygenases (ARHD) are proteins involved in AH degradation pathways.
Sanderson T. P. deSousa, Lucélia Cabral, Gileno Vieira Lacerda Júnior, Valéria M. Oliveira   +3 more
doaj   +1 more source

Biochemistry and occurrence of O-demethylation in plant metabolism

Frontiers in Physiology, 2010
Demethylases play a pivitol role in numerous biological processes from covalent histone modification and DNA repair to specialized metabolism in plants and microorganisms.
Jillian Hagel, Peter Facchini
doaj   +1 more source

Functional diversity of bacterial genes associated with aromatic hydrocarbon degradation in anthropogenic dark earth of Amazonia

Pesquisa Agropecuária Brasileira, 2012
The objective of this work was to evaluate the catabolic gene diversity for the bacterial degradation of aromatic hydrocarbons in anthropogenic dark earth of Amazonia (ADE) and their biochar (BC).
Mariana Gomes Germano, Fabiana de Souza Cannavan, Lucas William Mendes, Amanda Barbosa Lima, Wenceslau Geraldes Teixeira, Vivian Helena Pellizari, Siu Mui Tsai   +6 more
doaj   +1 more source

Oxygen concentration controls epigenetic effects in models of familial paraganglioma. [PDF]

PLoS ONE, 2015
Familial paraganglioma (PGL) is a rare neuroendocrine cancer associated with defects in the genes encoding the subunits of succinate dehydrogenase (SDH), a tricarboxylic acid (TCA) cycle enzyme.
Yeng F Her, Molly Nelson-Holte, Louis James Maher   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Increasing TET Expression and 5‐Hydroxymethylcytosine Formation by a Carbocyclic 5‐Aza‐2′‐deoxy‐cytidine Antimetabolite

Angewandte Chemie, EarlyView.
The carbocyclic Decitabine analog (cAzadC) incorporates as an antimetabolite weakly into the genome of growing tumor cells, where it triggers a genome‐wide demethylation and a surprisingly strong hydroxymethylation of cytosine, which translates into an efficient in vivo antitumor (AML) effect.
Maike Däther, Elsa Peev, Annika Fröhlich, Binje Vick, Sogol Fatourechi, Gilles Gasparoni, Matthias Heiss, Corinna C. Pleintinger, Emmanuel Asu Bisong, Hans Hurmiz, Davide Guglielminotti, Yasmin V. Gärtner, Tina Aumer, Karsten Spiekermann, Jörn Walter, Irmela Jeremias, Franziska R. Traube, Thomas Carell   +17 more
wiley   +2 more sources

2-Oxoglutarate: linking TCA cycle function with amino acid, glucosinolate, flavonoid, alkaloid and gibberellin biosynthesis

Frontiers in Plant Science, 2014
The tricarboxylic acid (TCA) cycle intermediate 2-oxoglutarate (2-OG) is used as an obligatory substrate in a range of oxidative reactions catalyzed by 2-OG-dependent dioxygenases.
Wagner L. Araújo, Wagner L. Araújo, Auxiliadora O Martins, Alisdair eFernie, Takayuki eTohge   +4 more
doaj   +1 more source