Results 11 to 20 of about 25,787 (305)

Substrate stereo‐specificity in tryptophan dioxygenase and indoleamine 2,3‐dioxygenase [PDF]

Proteins: Structure, Function, and Bioinformatics, 2010
AbstractThe first and rate‐limiting step of the kynurenine pathway, in which tryptophan (Trp) is converted to N‐formylkynurenine is catalyzed by two heme‐containing proteins, Indoleamine 2,3‐dioxygenase (IDO), and Tryptophan 2,3‐dioxygenase (TDO). In mammals, TDO is found exclusively in liver tissue, IDO is found ubiquitously in all tissues.
Luciana, Capece, Mehrnoosh, Arrar, Adrian E, Roitberg, Syun-Ru, Yeh, Marcelo A, Marti, Dario A, Estrin   +5 more
openaire   +2 more sources

Discovery and Characterization of a Second Mammalian Thiol Dioxygenase, Cysteamine Dioxygenase [PDF]

Journal of Biological Chemistry, 2007
There are only two known thiol dioxygenase activities in mammals, and they are ascribed to the enzymes cysteine dioxygenase (CDO) and cysteamine (2-aminoethanethiol) dioxygenase (ADO). Although many studies have been dedicated to CDO, resulting in the identification of its gene and even characterization of the tertiary structure of the protein ...
John E, Dominy, Chad R, Simmons, Lawrence L, Hirschberger, Jesse, Hwang, Relicardo M, Coloso, Martha H, Stipanuk   +5 more
openaire   +2 more sources

Application of nitroarene dioxygenases in the design of novel strains that degrade chloronitrobenzenes. [PDF]

, 2009
Widespread application of chloronitrobenzenes as feedstocks for the production of industrial chemicals and pharmaceuticals has resulted in extensive environmental contamination with these toxic compounds, where they pose significant risks to the health ...
Ju, Kou-San, Parales, Rebecca E
core   +1 more source

Structure of an aromatic-ring-hydroxylating dioxygenase – naphthalene 1,2-dioxygenase [PDF]

Structure, 1998
Pseudomonas sp. NCIB 9816-4 utilizes a multicomponent enzyme system to oxidize naphthalene to (+)-cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene. The enzyme component catalyzing this reaction, naphthalene 1,2-dioxygenase (NDO), belongs to a family of aromatic-ring-hydroxylating dioxygenases that oxidize aromatic hydrocarbons and related compounds to cis ...
Kauppi, Björn, Lee, Kyoung, Carredano, Enrique, Parales, Rebecca E, Gibson, David T, Eklund, Hans, Ramaswamy, S   +6 more
openaire   +2 more sources

Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones. [PDF]

PLoS ONE, 2011
2-Oxoglutarate (2OG) dependent dioxygenases are ubiquitous iron containing enzymes that couple substrate oxidation to the conversion of 2OG to succinate and carbon dioxide.
Hanne Korvald, Anne Margrethe Mølstad Moe, F Henning Cederkvist, Bernd Thiede, Jon K Laerdahl, Magnar Bjørås, Ingrun Alseth   +6 more
doaj   +1 more source

The MarR-Type Repressor MhqR Confers Quinone and Antimicrobial Resistance in Staphylococcus aureus [PDF]

, 2019
Aims: Quinone compounds are electron carriers and have antimicrobial and toxic properties due to their mode of actions as electrophiles and oxidants.
Fritsch, Verena Nadin, Loi, Vu Van, Busche, Tobias, Sommer, Anna, Tedin, Karsten, Nürnberg, Dennis J., Kalinowski, Jörn, Bernhardt, Jörg, Fulde, Marcus, Antelmann, Haike   +9 more
core   +1 more source

Synthetic, Spectroscopic and DFT Studies of Iron Complexes with Iminobenzo(semi)quinone Ligands: Implications for o-Aminophenol Dioxygenases [PDF]

, 2013
The oxidative CC bond cleavage of o-aminophenols by nonheme Fe dioxygenases is a critical step in both human metabolism (the kynurenine pathway) and the microbial degradation of nitroaromatic pollutants. The catalytic cycle of o-aminophenol dioxygenases (
Bittner, Michael M., Fiedler, Adam T., Krause, David S., Lindeman, Sergey V., Popescu, Cordina V.   +4 more
core   +2 more sources

Transcriptome-Stable Isotope Probing Provides Targeted Functional and Taxonomic Insights Into Microaerobic Pollutant-Degrading Aquifer Microbiota

Frontiers in Microbiology, 2018
While most studies using RNA-stable isotope probing (SIP) to date have focused on ribosomal RNA, the detection of 13C-labeled mRNA has rarely been demonstrated.
Lauren M. Bradford, Gisle Vestergaard, Gisle Vestergaard, András Táncsics, Baoli Zhu, Michael Schloter, Tillmann Lueders   +6 more
doaj   +1 more source

Isolation and characterization of Alicycliphilus denitrificans strain BC, which grows on benzene with chlorate as the electron acceptor [PDF]

, 2008
A bacterium, strain BC, was isolated from a benzene-degrading chlorate-reducing enrichment culture. Strain BC degrades benzene in conjunction with chlorate reduction.
Broeke, H., ten, Doesburg, W.C.J., van, Gerritse, J., Junca, H., Kieboom, C., van den, Langenhoff, A.A.M., Stams, A.J.M., Tan, N.C.G., Weelink, S.A.B.   +8 more
core   +2 more sources

Mangrove microniches determine the structural and functional diversity of enriched petroleum hydrocarbon-degrading consortia [PDF]

, 2010
In this study, the combination of culture enrichments and molecular tools was used to identify bacterial guilds, plasmids and functional genes potentially important in the process of petroleum hydrocarbon (PH) decontamination in mangrove microniches ...
Baek, Bale, Barac, Bartilson, Beeson, Benson, Bosch, Brito, Cecilia G. Flocco, Chou, Clarke, Costa, Das, Dennis, Dietmar H. Pieper, Dionisi, Ellen Krögerrecklenfort, Eltis, Entcheva, Eulberg, Fox, Fulthorpe, Germaine, Gomes, Gomes, Gomes, Gomes, Grayston, Götz, Harris, Head, Hedge, Heuer, Heuer, Hoff, Howard Junca, Izmalkova, Jaeger, Jeon, Junca, Koren, Kornelia Smalla, Krasowiak, Kuiper, Kummerová, Laurie, Leda C.S. Mendonça-Hagler, Lloyd-Jones, MacCormack, Margesin, Milling, Moser, Nakai, Nam, Neumann, Newton C.M. Gomes, Palleroni, Pleshakova, Proffitt, Pukall, Pérez-Pantoja, Ramette, Ramiro Vilchez, Rasmussen, Rodolfo Paranhos, Rodrigo Costa, Sambrook, Sar, Schlüter, Seo, Smalla, Smalla, Smits, Sobecky, Sota, Van Hamme, Venosa, Wang, Widada, Wilson, Wongsa, Yakimov   +81 more
core   +1 more source