Results 101 to 110 of about 38,805 (284)
InorganicsUtilizing all-atom molecular dynamics simulations, in the current study, we examine how three different graphene-based nanosheets (pristine graphene, graphene oxide and edge-functionalized graphene) impact the self-assembly mechanism of diphenylalanine ...
Elena Markopoulou +3 more
doaj +1 more source
Cell Biology. Clogging information flow in ALS. [PDF]
, 2014 Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disorder that causes a progressive loss of motor neurons, leading to paralysis and death typically within 2 to 5 years of onset.
A. D. Gitler, J. W. Paul, Kato, Sareen
core +1 more source
FREQUENCY OF DIPEPTIDES AND ANTIDIPEPTIDES
Computational and Structural Biotechnology Journal, 2013 Although it is reasonable to expect that the frequency of a generic dipeptide XY in proteins is the same of its counterpart YX, on the basis of an accurate statistical analysis of a large number of protein sequences, it appears that some dipeptides XY are considerably more frequent than their mirror images YX, referred to as antidipeptides.
openaire +4 more sources
Chemical Ligation of Backbone N‐hydroxylated Peptides
Chemistry – A European Journal, EarlyView.Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio +1 more
wiley +1 more source
Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches
Chemistry – A European Journal, EarlyView.We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal +4 more
wiley +1 more source
Free Energies of Reaction for Aqueous Glycine Condensation Chemistry at Extreme Temperatures
Geophysical Monograph Series, Page 271-283., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Matthew Kroonblawd, Nir Goldman
wiley +1 more source
Effect of Charge and Molecular Weight on Transdermal Peptide Delivery by Iontophoresis [PDF]
, 2018 Purpose: The study was conducted to investigate the impact of charge and molecular weight (MW) on the iontophoretic delivery of a series of dipeptides.
Abla, Nada +3 more
core
, 2007 We present an exhaustive study of more than 250 ab initio potential energy surfaces (PESs) of the model dipeptide HCO-L-Ala-NH2. The model chemistries (MCs) used are constructed as homo- and heterolevels involving possibly different RHF and MP2 ...
Alonso, J. L., Echenique, Pablo
core +2 more sources
Cytoskeleton, EarlyView.ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source
Molecules, 2019 Forward and backward stepwise regression (FR and BR, respectively) was applied for the structure–bioactivity prediction of angiotensin converting enzyme (ACE)-inhibitory/bitter-tasting dipeptides.
Monika Hrynkiewicz +4 more
doaj +1 more source