Results 111 to 120 of about 19,297 (179)

Bitter 2,5-Diketopiperazines From Cocoa Activate Human Bitter Taste Receptors. [PDF]

Mol Nutr Food Res
Schaefer S, Luna A, Behrens M.
europepmc   +1 more source

Fluorophenylalanine-Containing Dipeptides with Antibiofilm Activity Against <i>Pseudomonas aeruginosa</i> Discovered Through a Collaborative Undergraduate Research and Educational Program. [PDF]

Molecules
Dounay AB, Fuller AA, Lawton DRY, Buchman S, Bergstrom MF, Gilmore R, Hernly E, Hitchens J, Tee J, Tran C, Weiler N, Anderson GG, Hatton O, Marrs KA, Mudrack K, O'Donnell MJ, Schirch D, Sullivan K, Samaritoni JG, Scott WL.   +19 more
europepmc   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez, David Buedo, Alberto Vega‐Peñaloza, Kian Gosling, Stuart C. D. Kennington, Bart Limburg, Xavier Companyó   +6 more
wiley   +2 more sources

Sequence Inversion Dictates the Antiproliferative Activity of Bidirectional Tryptophan-Containing Dipeptide Libraries. [PDF]

J Pept Sci
Díaz JB, Khan AN, González-Bakker A, Padrón JM.   +3 more
europepmc   +1 more source

Unified Approach for the Synthesis of Close Analogues of Reverse‐Prenylated Hexahydropyrrolo Indole Alkaloids

European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
A simple, modular, and unified strategy for the synthesis of reverse‐prenylated hexahydropyrrolo indole alkaloids has been developed. An unusual retrosynthetic disconnection allows for the late introduction of a side chain, which distinguishes many members of this class of natural products.
Daniel Schmelzer, Carina S. Wencke, Christian B. W. Stark   +2 more
wiley   +1 more source

Analysis and Annotation of c-Type Ions in Peptide Mass Spectral Libraries. [PDF]

J Proteome Res
Burke MC, Yang X, Liang Y, Neta P, Stein SE.   +4 more
europepmc   +1 more source

Quantification of Carnosine and Anserine in Diverse Meat Matrices via Optimized Extraction and Validated HPLC-DAD. [PDF]

Methods Protoc
Kaewkhow C, Chumang C, Pantu P, Luksirikul P, Pongprayoon P, Koonawootrittriron S, Suwanasopee T, Saleepoch T, Kityakarn S.   +8 more
europepmc   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +2 more sources

Circulating Dipeptides in Cancer: Degradation Fragments or Functional Metabolites? [PDF]

Int J Mol Sci
Kim KH, Yoo BC.
europepmc   +1 more source