Results 111 to 120 of about 18,468 (228)
Circulating Dipeptides in Cancer: Degradation Fragments or Functional Metabolites? [PDF]
Kim KH, Yoo BC.
europepmc +1 more source
ABSTRACT Mycorrhizal symbiosis shapes plant growth and stress resilience. Here, we compared physiological and molecular responses of poplars (P. x canescens) colonised by Paxillus involutus (Pi) or Cenococcum geophilum (Cg) under control conditions, drought stress and recovery.
Huili Shi, Zhuchou Lu, Andrea Polle
wiley +1 more source
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng +4 more
wiley +2 more sources
Carnosine‐Related Metabolism in Rat Cardiomyocytes and Human Heart Tissue
Carnosine‐related metabolism in rat cardiomyocytes and human heart tissue. Jade V Creighton, Lívia de Souza Gonçalves, Saulo Gil, Bianca Scigliano Vargas, Leonardo Jensen, Marisa Helena Gennari de Medeiros, Hamilton Roschel, Mark D Turner, Craig L Doig, Guilherme Giannini Artioli, Craig Sale.
Jade V. Creighton +10 more
wiley +1 more source
Post‐Translational Isoaspartate Promotes Amyloid Formation in β2‐Microglobulin
Chemical synthesis of five β2‐microglobulin (β2m) variants reveals the structural impact of Asn deamidation. By introducing Asp or isoAsp at susceptible Asn‐Gly sequences, we demonstrate that isoAsp17 formation specifically accelerates amyloid fibril formation, highlighting its potential contribution to dialysis‐related amyloidosis.
Ryuji Kawakami +5 more
wiley +2 more sources
Partial hepatectomy (PH) reshapes gut microbiota composition, resulting in the release of microbial metabolites and components, including short chain fatty acids (SCFAs)/β‐hydroxybutyric acid (BHB), bacterial DNA and extracellular vesicles (EVs), bile acids (deoxycholic acid, DCA), and aminobenzoate degradation products.
Roberto Loi +3 more
wiley +1 more source
Dipeptide Transport Systems at the Interface of Peptide Metabolism and Drug Delivery in Cancer. [PDF]
Kim KH, Yoo BC.
europepmc +1 more source
Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner +2 more
wiley +1 more source
Dipeptide photodegradation under copper ion influence suggests protective second-shell design in copper-binding proteins. [PDF]
Shi X +5 more
europepmc +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source

