Results 121 to 130 of about 19,297 (179)

Downsizing the Histone H3–H4 Quaternary Structure Into Foldamer Mimetics Yields High‐Affinity and Cell‐Permeable Ligands of ASF1

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
We present a foldamer strategy to downsize the histone H3‐H4 quaternary structure into high‐affinity, medium‐sized binders (∼2 kDa) for the histone chaperone ASF1. Our peptide‐oligourea chimeras, designed through structure‐guided optimization and foldamer chemistry, recapitulate the natural H3‐H4 dimer binding mode while demonstrating plasma stability ...
Bo Li, Marie E. Perrin, Emma Maillard, Arthur Vitard, Gwenaëlle Moal, Johanne Mbianda, Christophe André, Magda Teixeira Nunes, Marie Vandamme, Guillaume Pinna, Céline Douat, Emmanuelle Thinon, Raphaël Guerois, Pierre Legrand, Gilles Guichard, Francoise Ochsenbein   +15 more
wiley   +2 more sources

A Dipeptide Module Substitution-Based Strategy for the Modification and Evaluation of ACE Inhibitory Peptides. [PDF]

Foods
Liang Q, Wang S, Sun N, Zhu C, Liu Z, Mou H.   +5 more
europepmc   +1 more source

Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A strategy for accelerated photochemical reaction discovery is reported that harnesses the dynamic speciation of copper complexes, driven by their labile metal–ligand bonds. This platform simplifies reaction screening by combining an earth‐abundant copper(II) salt with commercially available ligands, which reversibly generate multiple catalytic species
Alessio Regni, Siyu Liang, Supreeta Sen, Hailey Hendricks, Xijue Wu, Matthew V. Pecoraro, Jose B. Roque   +6 more
wiley   +2 more sources

Therapy-resistant lymphomas may want nucleotides, but they just need to grow. [PDF]

J Clin Invest
Carmona-Fontaine C.
europepmc   +1 more source

Complete NMR assignment for 275 of the most common dipeptides in intrinsically disordered proteins. [PDF]

Sci Data
Rindfleisch T, Taule EF, Miettinen MS, Underhaug J.   +3 more
europepmc   +1 more source

From Dipeptide Systems to Polypeptides: Evolution of Mutual Information. [PDF]

ACS Omega
Javaheri Moghadam M, Boguslawski K, Tecmer P, De Baerdemacker S.   +3 more
europepmc   +1 more source

Phosphorus Chemistry and the Origin of Life: From N-Phosphoryl Amino Acid to Protocell. [PDF]

Acc Chem Res
Ying J, Liu Y, Fu S, Gao X, Zhao Y.
europepmc   +1 more source

Suspect screening-based LC-HRMS characterization of short-chain peptide hydrolysates from marine macroalgae. [PDF]

Anal Bioanal Chem
Achahbar H, Cerrato A, Durán-Guerrero E, Hernández I, Laganà A, Lucà E, Montone CM, Taglioni E, Capriotti AL.   +8 more
europepmc   +1 more source

SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation. [PDF]

J Clin Invest
Yang H, Zingaro VA, Boardman K, Noronha A, Guney E, Xue L, Hoigebazar S, Liu I, Miglani S, Chen S, Vu H, Wen KW, Nguyen HG, Goodarzi H, DeBerardinis RJ, Ruggero D.   +15 more
europepmc   +1 more source

<i>N</i>-Terminal Coumarin Derivatization-Aided <i>De Novo</i> Peptide Sequencing and Its Application to Peptidomics Using LC-Trapped Ion Mobility Spectrometry-qTOF/MS. [PDF]

Anal Chem
Luan H, Toyama Y, Honda F, Asai R, Katagihara R, Xiao Y, Nakamura S, Matsui T, Tanaka M.   +8 more
europepmc   +1 more source