Results 81 to 90 of about 26,326 (279)

Discovery of Potent Dengue Virus NS2B-NS3 Protease Inhibitors Among Glycyrrhizic Acid Conjugates with Amino Acids and Dipeptides Esters

Viruses
This study investigated a library of known and novel glycyrrhizic acid (GL) conjugates with amino acids and dipeptide esters, as inhibitors of the DENV NS2B-NS3 protease. We utilized docking algorithms to evaluate the interactions of these GL derivatives
Yu-Feng Lin, Hsueh-Chou Lai, Chen-Sheng Lin, Ping-Yi Hung, Ju-Ying Kan, Shih-Wen Chiu, Chih-Hao Lu, Svetlana F. Petrova, Lidia Baltina, Cheng-Wen Lin   +9 more
doaj   +1 more source

Comprehensive Dipeptide Analysis Revealed Cancer-Specific Profile in the Liver of Patients with Hepatocellular Carcinoma and Hepatitis

Metabolites, 2020
As the physical properties and functionality of dipeptides differ from those of amino acids, they have attracted attention in metabolomics; however, their functions in vivo have not been clarified in detail.
Hitoshi Ozawa, Akiyoshi Hirayama, Futaba Shoji, Midori Maruyama, Kumi Suzuki, Hisami Yamanaka-Okumura, Hiroshi Tatano, Yuji Morine, Tomoyoshi Soga, Mitsuo Shimada, Masaru Tomita   +10 more
doaj   +1 more source

ESI-MSn study on the fragmentation of protonated cyclic-dipeptides [PDF]

, 2009
Cyclic dipeptides are relatively simple compounds that can exhibit a great variety of important biological activities. The fragmentation pathways of protonated cyclic dipeptides have been studied by electrospray ionization multistage mass spectrometry ...
Guo, Y. C., Zong, X. K., Zhao, Y. F., Liao, X. C., 赵玉芬, Cao, S. X.   +5 more
core  

Papain‐catalyzed synthesis of dipeptides

, 1988
Groeger U, Stehle P, Fürst P, Leuchtenberger W, Drauz K. Papain‐catalyzed synthesis of dipeptides. Food Biotechnology.
Stehle, P., Fürst, P., Leuchtenberger, Wolfgang, Groeger, U., Drauz, K.   +4 more
core   +1 more source

In vitro and in vivo Evaluation on the Safety and Efficacy of a Brand-New Intracutaneous Filler with α1-R-Collagen

Clinical, Cosmetic and Investigational Dermatology, 2021
Fabio Rinaldi,1,2 Daniela Pinto,1,2 Anna Trink,2 Giammaria Giuliani,1 Adele Sparavigna3 1Giuliani SpA, Research and Development Department, Milan, Italy; 2IHRF, International Hair Research Foundation, Milan, Italy; 3Derming, Clinical Research, and ...
Rinaldi F, Pinto D, Trink A, Giuliani G, Sparavigna A   +4 more
doaj  

Proline-Based Cyclic Dipeptides from Korean Fermented Vegetable Kimchi and from Leuconostoc mesenteroides LBP-K06 Have Activities against Multidrug-Resistant Bacteria

Frontiers in Microbiology, 2017
Lactobacillus plantarum and Leuconostoc mesenteroides play a prominent role as functional starters and predominant isolates in the production of various types of antimicrobial compound-containing fermented foods, especially including kimchi.
Min-Kyu Kwak, Sa-Ouk Kang, Rui Liu, Andrew H. Kim   +3 more
doaj   +1 more source

Dipeptides as co-formers in co-amorphous systems

, 2019
Drug-amino acid co-amorphous systems have become increasingly well-investigated systems to improve dissolution rate of poorly water-soluble drugs. In this study, dipeptides were investigated as co-formers for co-amorphous systems based on the hypothesis ...
Pedersen, Daniel Sejer, Wu, Wenqi, Knuhtsen, Astrid, Schnitzkewitz, Jan, Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger   +6 more
core   +1 more source

Image5_C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response.TIF

, 2022
Proline:arginine (PR) poly-dipeptides from the GGGGCC repeat expansion in C9orf72 have cytotoxicity and bind intermediate filaments (IFs). However, it remains unknown how PR poly-dipeptides affect cytoskeletal organization and focal adhesion (FA ...
Masaya Matsubayashi (9030926), Takao Kiriyama (9030941), Riko Nagata (9030959), Mari Nakanishi (9030977), Sotaro Kikuchi (10938477), Noriyoshi Isozumi (11895505), Tomo Shiota (9030932), Kazuma Sugie (731203), Kazuaki Nagayama (12277133), Shinko Kobashigawa (9030974), Eiichiro Mori (352015), Hitoki Nanaura (9030929), Yoshito Yamashiro (12277136)   +12 more
core   +1 more source

Image3_C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response.TIF

, 2022
Proline:arginine (PR) poly-dipeptides from the GGGGCC repeat expansion in C9orf72 have cytotoxicity and bind intermediate filaments (IFs). However, it remains unknown how PR poly-dipeptides affect cytoskeletal organization and focal adhesion (FA ...
Masaya Matsubayashi (9030926), Takao Kiriyama (9030941), Riko Nagata (9030959), Mari Nakanishi (9030977), Sotaro Kikuchi (10938477), Noriyoshi Isozumi (11895505), Tomo Shiota (9030932), Kazuma Sugie (731203), Kazuaki Nagayama (12277133), Shinko Kobashigawa (9030974), Eiichiro Mori (352015), Hitoki Nanaura (9030929), Yoshito Yamashiro (12277136)   +12 more
core   +1 more source

Molecular Recognition and Modification Strategies of Umami Dipeptides with T1R1/T1R3 Receptors

Molecules
Umami is a fundamental taste sensation, often described as a delicious and pleasant flavor perception. To enhance or complement the original flavor and meet the tastes of diverse regions, umami dipeptides have been extensively utilized in global food ...
Kaixuan Hu, Guangzhou Sun, Wentong Yu, Mengyu Zhang, Shuang Wang, Yujie Cao, Dongling Hu, Li Liang, Gang He, Jianping Hu, Wei Liu   +10 more
doaj   +1 more source