Results 61 to 70 of about 38,805 (284)

Muscle histidine-containing dipeptides are elevated by glucose intolerance in both rodents and men. [PDF]

PLoS ONE, 2015
Muscle carnosine and its methylated form anserine are histidine-containing dipeptides. Both dipeptides have the ability to quench reactive carbonyl species and previous studies have shown that endogenous tissue levels are decreased in chronic diseases ...
Sanne Stegen, Inge Everaert, Louise Deldicque, Silvia Vallova, Barbora de Courten, Barbara Ukropcova, Jozef Ukropec, Wim Derave   +7 more
doaj   +1 more source

RGS4 is arginylated and degraded by the N-end rule pathway in vitro [PDF]

, 2000
The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. We used an expression-cloning screen to search for mouse proteins that are degraded by the ubiquitin/proteasome-dependent N-end rule pathway in a ...
Davydov, Ilia V., Varshavsky, Alexander
core   +1 more source

Cucurbit[8]Uril Achieved Single‐Molecule Chiral Transfer to Supramolecular Circularly Polarized Luminescence

Advanced Science, EarlyView.
A single‐molecule cascade supramolecular system comprising L/D‐FPy, CB[8], and SC4AD serves as an efficient light‐harvesting platform. It facilitates cascade energy transfer and chiral transfer to acceptor dyes. Co‐assembly with a PVA matrix produces a multicolor solid film that exhibits enhanced luminescence dissymmetry factors (glum), enabling ...
Yongxue Li, Jie Wu, Weiheng Zhang, Hengzhi Zhang, Wei‐Lei Zhou, Yu Liu   +5 more
wiley   +1 more source

Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against Aspergillus Species

Biomolecules
In recent years, fungal infections have emerged as a significant health concern across veterinary species, especially in livestock such as cattle, where fungal diseases can result in considerable economic losses, as well as in humans.
Tatevik Sargsyan, Lala Stepanyan, Henrik Panosyan, Heghine Hakobyan, Monika Israyelyan, Avetis Tsaturyan, Nelli Hovhannisyan, Caterina Vicidomini, Anna Mkrtchyan, Ashot Saghyan, Giovanni N. Roviello   +10 more
doaj   +1 more source

Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones [PDF]

, 2018
Because of the beneficial effect of a trifluoromethyl group on the biological properties of bioactive compounds on the one hand and the versatile synthetic potential of beta-lactams on the other hand, 4-CF3-beta-lactams comprises interesting entities for
D'hooghe, Matthias, Dao Thi, Hang, Van Nguyen, Tuyen   +2 more
core   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Nematophin, an Antimicrobial Dipeptide Compound From Xenorhabdus nematophila YL001 as a Potent Biopesticide for Rhizoctonia solani Control

Frontiers in Microbiology, 2019
This study was conducted to purify and identify metabolites of antimicrobial activity against phytopathogens from Xenorhabdus nematophila YL001. Three dipeptide compounds were purified from its cell-free cultural broth and identified as (±)-nematophin ...
Shujing Zhang, Qi Liu, Yunfei Han, Jinghua Han, Zhiqiang Yan, Yonghong Wang, Xing Zhang   +6 more
doaj   +1 more source

Inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase enzyme by dipeptides identified in dry-cured ham

Food Production, Processing and Nutrition, 2021
High cholesterolemia is a key risk factor for the development of cardiovascular diseases, which are the main cause of mortality in developed countries.
Alejandro Heres, Leticia Mora, Fidel Toldrá   +2 more
doaj   +1 more source

The role of histidine dipeptides on postmortem acidification of broiler muscles with different energy metabolism

Poultry Science, 2021
It is generally held that the content of several free amino acids and dipeptides is closely related to the energy-supplying metabolism of skeletal muscles.
Giulia Baldi, Francesca Soglia, Luca Laghi, Adele Meluzzi,, Massimiliano Petracci   +4 more
doaj   +1 more source

Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Histidyl dipeptides such as carnosine are present in a micromolar to millimolar range in mammalian hearts. These dipeptides facilitate glycolysis by proton buffering.
Keqiang Yan, Zhanlong Mei, Jingjing Zhao, Md Aminul Islam Prodhan, Detlef Obal, Kartik Katragadda, Benjamin Doelling, David Hoetker, Dheeraj Kumar Posa, Liqing He, Xinmin Yin, Jasmit Shah, Jianmin Pan, Shesh Rai, Pawel Konrad Lorkiewicz, Xiang Zhang, Siqi Liu, Aruni Bhatnagar, Shahid P. Baba   +18 more
doaj   +1 more source