Results 51 to 60 of about 26,326 (279)
Advanced Science, EarlyView.Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou +10 more
wiley +1 more source
Angewandte Chemie, EarlyView.Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
Synthesis of S- and N,S-Heterocycle–Dipeptide Conjugates for Supramolecular Hydrogel Formation
MoleculesSmall peptides with aromatic nuclei at the N-terminus have been shown to form bioactive, biocompatible, and biodegradable supramolecular peptide hydrogels.
Ana-Morgana G. P. Silva +5 more
doaj +1 more source
Amino Acid-Derived Metabolites from the Ascidian Aplidium sp.
Marine Drugs, 2015 Four new iodobenzene-containing dipeptides (1–4), a related bromotryptophan-containing dipeptide (5), and an iodophenethylamine (6) were isolated from the ascidian Aplidium sp. collected off the coast of Chuja-do, Korea.
Tae Hyung Won +7 more
doaj +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
Advanced Science, EarlyView.WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes
Angewandte Chemie, EarlyView.A strategy for accelerated photochemical reaction discovery is reported that harnesses the dynamic speciation of copper complexes, driven by their labile metal–ligand bonds. This platform simplifies reaction screening by combining an earth‐abundant copper(II) salt with commercially available ligands, which reversibly generate multiple catalytic species
Alessio Regni +6 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez +6 more
wiley +2 more sources
Frontiers in Plant ScienceIntroductionHigh-throughput phenotyping technologies together with metabolomics analysis can speed up the development of highly efficient and effective biostimulants for enhancing crop tolerance to drought stress. The aim of this study was to examine the
Marzia Leporino +6 more
doaj +1 more source
Synthèse des dipeptides d’intérêt biologique [PDF]
, 2015 des dipeptides d’intérêt biologique [texte imprimé] / ATMANI, Nadia, Auteur. - 2015. - 48p: ill.,...; 30cm. Résumé : Le sujet de ce mémoire est la synthèse des dipeptides à partir des aminoacides, avec comme objectif, l’élaboration de quelques ...
Atmani, Nadia
core
Advanced Science, EarlyView.CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen +19 more
wiley +1 more source