Advanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.Selective late‐stage modification of N‐terminal phenylalanine short peptides is achived by visible‐light initiated reaction with N‐iodoimides in a debenzylation–amination process. This metal‐free method permits the incorporation of N‐containing heterocycles into the α‐position of the peptide backbone.
Guillermo Morales‐Ortega +4 more
wiley +1 more source
Untargeted metabolomics identifies a bacterial cyclic dipeptide that induces resistance to a rust fungus of beans. [PDF]
Sci RepCooper B, Yang R, Campbell KB.
europepmc +1 more source
Self‐Immolative Systems in Diagnostic and Therapeutic Applications
ChemMedChem, Volume 21, Issue 5, 13 March 2026.Self‐Immolative Systems enable the precise, residue‐free release of active molecules, drugs, probes, or sensors, via cyclization or elimination, triggered by specific stimuli. Their versatility drives advances in drug delivery, diagnostics, nanotechnology, materials chemistry, and biosensing, offering chemists control over molecular activation and ...
Windbedema Prisca Ouédraogo +2 more
wiley +1 more source
The solute-binding proteins DppA1-5 of Pseudomonas aeruginosa have distinct substrate profiles. [PDF]
Sci RepPlöchl K, Böttcher T.
europepmc +1 more source
Catalytic Amyloids: Turning Fibrils Into Biocatalysts
Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito +3 more
wiley +1 more source
Synthetic Studies Towards Darobactin A
Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.The urgent need for new antibiotics led us to develop a new methodology for the synthesis of the natural product darobactin A selectively targeting gram‐negative bacteria. This study provides new insights into the synthesis of strained indole‐containing macrocycles.
Till Steiner +4 more
wiley +1 more source
The Effect of Serum Carnosinase on the Tissue Distribution of Imidazole Dipeptides After Their Oral Administration in Golden Hamsters. [PDF]
NutrientsShiotani S +5 more
europepmc +1 more source
Integrated In Silico - In Vitro Study Investigating Dipeptides as Chorismate Synthase Modulators: Spotlight on Its Mechanism of Action. [PDF]
Glob ChallPedroni L +4 more
europepmc +1 more source
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides. [PDF]
J Pept SciMoriyama Y, Sada H, Nanjo T.
europepmc +1 more source
Myocardial protection by acidic amino acids and natural dipeptides: potential for an underused resource. [PDF]
Amino AcidsKing N.
europepmc +1 more source