Design of Lipopeptides and dsRNA‐Lipopeptide Complexes for Sprayable RNAi‐Based Plant Protection
Lipopeptide surfactants self‐assemble into nanostructure carriers that complex, protect, and deliver dsRNA, establishing structure–function relationships for next‐generation RNAi‐based insect control. ABSTRACT Broad‐spectrum insecticides persist in the environment, affecting non‐target organisms and selecting for resistant pest populations. In contrast,
Pascal Geisler +3 more
wiley +1 more source
Electrochemical α-acyloxylation of dibenzoylmethane with C-terminal carboxylic acids for peptide and drug diversification. [PDF]
Jiang S +6 more
europepmc +1 more source
Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek +3 more
wiley +1 more source
Dipeptide Transport Systems at the Interface of Peptide Metabolism and Drug Delivery in Cancer. [PDF]
Kim KH, Yoo BC.
europepmc +1 more source
DPP-4 inhibitory and insulin-signaling-modulating potential of <i>Allomyrina dichotoma</i> larval protein hydrolysate. [PDF]
Han JH, Auh JH.
europepmc +1 more source
Elderly human donor microbiota disrupts intestinal barrier integrity and reshapes host metabolic and mucosal transcriptional profiles in human microbiota‐associated pigs. Integrated multi‐omics analyses identify coordinated microbial, metabolic, and host alterations associated with age‐related intestinal decline.
Jiaxin Wang +19 more
wiley +1 more source
Dipeptide photodegradation under copper ion influence suggests protective second-shell design in copper-binding proteins. [PDF]
Shi X +5 more
europepmc +1 more source
ABSTRACT Background Skin aging, a key aspect of physiological decline, markedly affects appearance, making strategies to delay it vital for quality of life. Materials and Methods We applied network medicine analysis to screen herbal medicines from the TCMSP database, yielding an anti‐skin aging formula, ZiYuShuang (ZYS).
Yingpeng Tong +6 more
wiley +1 more source
Direct Regioselective para‐Fluorination via I(I)/I(III) Catalysis
A direct, para‐selective fluorination by I(I)/I(III) catalysis is disclosed that does not require substrate pre‐functionalization. This strategy leverages the Leonard link inherent to phenylpropanoate and phenylpropanamides to promote a spirocyclization/para‐selective sequence. The C3‐side chain maps onto a range of common drug scaffolds and allows the
Christoph Roblick +5 more
wiley +2 more sources
Inhibition of Candida albicans yeast-to-hypha transition and virulence by cyclic dipeptides derived from probiotic Aeromonas veronii V03. [PDF]
Sekar J +5 more
europepmc +1 more source

