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A silaproline-containing dipeptide

Acta Crystallographica Section C Crystal Structure Communications, 2000
The silaproline-containing dipeptide N-(3, 3-dimethyl-1-pivaloyl-1-aza-3-sila-5-cyclopentylcarbonyl)-L- alanine isopropylamide, C(17)H(33)N(3)O(3)Si, has two independent molecules in the asymmetric unit and each adopts a beta-II folded conformation, where the amide on the terminal C interacts intramolecularly with the pivaloyl O atom. The five-membered
B, Vivet   +5 more
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Conformation of dipeptides

Biopolymers, 1969
AbstractThe amide bond in L,L‐ and L,D‐α‐chloropropionylalanine methyl ester is shown to be trans by molar polarization and infrared spectroscopy. In these dipeptide diastereoisomer analogues, therefore, differences in physical properties, i.e., melting points, crystalline forms, gas chromatographic mobilities, etc., depend on preferred molecular ...
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Human renin inhibiting dipeptide

European Journal of Pharmacology, 1986
KRI-1177, a dipeptide containing nor-statine inhibited renin activity in human and Japanese monkey plasma to a markedly greater extent than that in dog, rabbit and rat plasma. The systemic blood pressure of anesthetized monkeys was lowered by intravenous injections of this compound which also reduced plasma renin activity and concentration of ...
N, Toda   +4 more
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Fluoroolefin dipeptide isosteres -II.

Tetrahedron Letters, 1990
Abstract The syntheses of Gly-Gly and racemic Phe-Gly fiuoroolefin dipeptide isosteres are described, the first examples of a new class of peptide analogues.
Thomas Allmendinger   +2 more
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Related dipeptide and characteristic dipeptide of optimal pH in α-amylase

Biochemical and Biophysical Research Communications, 2002
Alpha-amylase is an enzyme of great significance to industry, but most alpha-amylases are unstable at lower pH. In this paper, we have studied the related dipeptide and characteristic dipeptide of optimal pH in alpha-amylase. On analysis, it gives the explicit results as follows: (1) Ten dipeptides are associated with alpha-amylase's optimal pH. AH, DV,
Ge-Xin, Zhang, Wei-Jiang, Li
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Imidazole Dipeptides

2015
Carnosine in the Context of Histidine Containing Dipeptides Carnosine and its Homologues in Foods The Chemistry of Imidazole Dipeptides The Chemistry of Carnosine Derivatives Chiral Carnosine The Biochemistry of Enzymes Producing Carnosine and Anserine The Biochemistry of Anserine and Carnosine Degrading Enzymes Carnosine and Derivatives as Inhibitors ...
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A Bisnitroxyl Dipeptide

Liebigs Annalen der Chemie, 1992
AbstractThe dinitroxylamide 8 is synthesized from the monomer 4‐amino‐4‐carboxy‐2,2,6,6‐tetramethylpiperidine‐1‐oxyl (2). The benzyloxycarbonyl group as amino protective group and the methoxy group as carboxyl protective group have been introduced. The acylation of compound 3 with compound 4 is carried out in the presence of dicyclohexylcarbodiimide ...
Lothar Dulog, Wei Wang
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Glutamine dipeptides in clinical nutrition

Nutrition, 1997
Glutamine is a conditional indispensable amino acid during stress. However, limited solubility and instability of glutamine prevent its addition to presently available nutritional preparations. To overcome these drawbacks, we propose the dipeptide concept by which stable and highly soluble synthetic glutamine containing dipeptides are used.
P, Fürst, K, Pogan, P, Stehle
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Determination of dipeptides in urine

Clinica Chimica Acta, 1974
Abstract The urine of a patient suffering from dermatological purpura was examined for dipeptides by combined gas chromatography—mass spectrometry. Several dipeptides were identified and all were of the general formula, R proline, where R is one of the amino acids, glycine, alanine, leucine, isoleucine, valine, phenylalanine, glutamic acid, aspartic ...
R A, Johnstone   +5 more
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Simulated dipeptide recognition by vancomycin

Journal of Molecular Recognition, 1997
The antimicrobial activity of vancomycin and related glycopeptide antibiotics is due to stereospecific recognition of polypeptide components in bacterial cell walls. To better understand how these antibiotics recognize polypeptide determinants, we have developed dynamic models of the complexes formed by the vancomycin aglycon and two different ...
D, Li   +6 more
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