Results 21 to 30 of about 26,326 (279)

Multi-tissue Metabolic GWAS and Drought-Responsive Multi-omics Reveal the Genetic Basis of the Quinoa Metabolome. [PDF]

Adv Sci (Weinh)
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
von Steimker J, Rey EL, Stanschewski C, Wendenburg R, Klemmer A, Macho M, Thirumalaikumar VP, Saber NO, Skirycz A, Fernie AR, Tester M, Alseekh S.   +11 more
europepmc   +2 more sources

Studies on the Self-Assembly of Dipeptides [PDF]

, 2021
Understanding the structure of amino acids and peptides is a major part of biochemistry courses. The research project discussed here will focus on the development of an experiment showcasing the construction of dipeptides that allows biochemistry ...
Lybarger, Colton, Akmel, Vadeah
core   +2 more sources

Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition

Molecules, 2022
Novel semisynthetic coumarin derivatives were synthesized to be developed as chemotherapeutic anticancer agents through topoisomerase II, VEGFR2 inhibition that leads to apoptotic cancer cell death.
Mohamed S. Gomaa, Ibrahim A. I. Ali, Gaber El Enany, El Sayed H. El Ashry, Samir M. El Rayes, Walid Fathalla, Abdulghany H. A. Ahmed, Samar A. Abubshait, Haya A. Abubshait, Mohamed S. Nafie   +9 more
doaj   +1 more source

Fine‐Tuning Supramolecular Assemblies by Controlling Micellar Aggregates

Macromolecular Materials and Engineering, 2023
Supramolecular assembly can be used to fabricate complex functional materials by organizing simple building blocks. However, it is difficult to control the hierarchical assembly across multiple length scales.
Dipankar Ghosh, Libby J. Marshall, Giuseppe Ciccone, Wanli Liu, Adam Squires, Annela Seddon, Massimo Vassalli, Dave J. Adams   +7 more
doaj   +1 more source

Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle

Metabolites, 2021
Sleep is a state in which important restorative and anabolic processes occur. Understanding changes of these metabolic processes during the circadian rhythm in the brain is crucial to elucidate neurophysiological mechanisms important for sleep function ...
Theodosia Vallianatou, Nicholas B. Bèchet, Mario S. P. Correia, Iben Lundgaard, Daniel Globisch   +4 more
doaj   +1 more source

Antibacterial and Antibiofilm Effects of Allelopathic Compounds Identified in Medicago sativa L. Seedling Exudate against Escherichia coli

Molecules, 2023
In this study, the allelopathic properties of Medicago sativa L. (alfalfa) seedling exudates on the germination of seeds of various species were investigated.
Sara Abouzeid, Ulrike Beutling, Engy Elekhnawy, Dirk Selmar   +3 more
doaj   +1 more source

The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship

Molecules, 2020
The translocator protein (TSPO, 18 kDa) plays an important role in the synthesis of neurosteroids by promoting the transport of cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step in neurosteroidogenesis ...
Tatiana A. Gudasheva, Olga A. Deeva, Andrey S. Pantileev, Grigory V. Mokrov, Inna V. Rybina, Milada A. Yarkova, Sergei B. Seredenin   +6 more
doaj   +1 more source

Self-Assembled Short Peptide Nanostructures: ‘’Dipeptides’’

MANAS: Journal of Engineering, 2023
Dipeptides are short peptide molecules formed by the peptide bond between two amino acids, and they play significant roles in various biological processes (such as protein synthesis, nutrient absorption, cellular signaling, immune response).
Mehmet Odabaşı, Ömür Acet, Tuba Gök, Burcu Önal Acet, Emrah Dikici   +4 more
doaj   +1 more source

The Antiproliferative and Apoptotic Effect of a Novel Synthesized S-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos

Molecules, 2021
Several derivatives containing morpholine/piperidine, anilines, and dipeptides as pending moieties were prepared using s-triazine as a scaffold. These compounds were evaluated for their anticancer activity against two human breast cancer cell lines (MCF ...
Azizah M. Malebari, Rakia Abd Alhameed, Zainab Almarhoon, Muhammad Farooq, Mohammad A. M. Wadaan, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham   +8 more
doaj   +1 more source

Proteogenic Dipeptides Are Characterized by Diel Fluctuations and Target of Rapamycin Complex-Signaling Dependency in the Model Plant Arabidopsis thaliana

Frontiers in Plant Science, 2021
As autotrophic organisms, plants capture light energy to convert carbon dioxide into ATP, nicotinamide adenine dinucleotide phosphate (NADPH), and sugars, which are essential for the biosynthesis of building blocks, storage, and growth.
Maria Juliana Calderan-Rodrigues, Marcin Luzarowski, Carolina Cassano Monte-Bello, Romina I. Minen, Boris M. Zühlke, Boris M. Zühlke, Zoran Nikoloski, Zoran Nikoloski, Aleksandra Skirycz, Aleksandra Skirycz, Camila Caldana   +10 more
doaj   +1 more source