Results 11 to 20 of about 19,297 (179)
The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship
Molecules, 2020 The translocator protein (TSPO, 18 kDa) plays an important role in the synthesis of neurosteroids by promoting the transport of cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step in neurosteroidogenesis ...
Tatiana A. Gudasheva +6 more
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Self-Assembled Short Peptide Nanostructures: ‘’Dipeptides’’
MANAS: Journal of Engineering, 2023 Dipeptides are short peptide molecules formed by the peptide bond between two amino acids, and they play significant roles in various biological processes (such as protein synthesis, nutrient absorption, cellular signaling, immune response).
Mehmet Odabaşı +4 more
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Molecules, 2021 Several derivatives containing morpholine/piperidine, anilines, and dipeptides as pending moieties were prepared using s-triazine as a scaffold. These compounds were evaluated for their anticancer activity against two human breast cancer cell lines (MCF ...
Azizah M. Malebari +8 more
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The Synthesis of (2R)-Aziridine-2-carboxylic Acid Containing Dipeptides
Acta Chimica Slovenica, 2022 Optimized conditions for the synthesis of fully deprotected (2R)-aziridine containing dipeptides are described. Preparation of fully protected N- and C- terminal aziridine containing dipeptides was found to be straightforward and high yielding for the ...
Samo Kuzmič, Martina Hrast, Rok Frlan
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Feedback Regulation of Cathepsin C by the Propeptide Dipeptides of Granzymes A and B
Acta Chimica Slovenica, 2019 Granzymes A and B are activated by proteolytic removal of their N-terminal dipeptides by cathepsin C (dipeptidyl-peptidase I). However, the possible physiological role of the cleaved dipeptides Glu-Lys and Gly-Glu is not yet understood.
Janja Božič, Iztok Dolenc
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Molecules, 2023 Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben +6 more
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Frontiers in Plant Science, 2021 As autotrophic organisms, plants capture light energy to convert carbon dioxide into ATP, nicotinamide adenine dinucleotide phosphate (NADPH), and sugars, which are essential for the biosynthesis of building blocks, storage, and growth.
Maria Juliana Calderan-Rodrigues +10 more
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Nearest-Neighbor Interactions and Their Influence on the Structural Aspects of Dipeptides
Biochemistry Research International, 2013 In this theoretical study, the role of the side chain moiety of C-terminal residue in influencing the structural and molecular properties of dipeptides is analyzed by considering a series of seven dipeptides.
Gunajyoti Das, Shilpi Mandal
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Chimica Techno Acta, 2022 Neurodegenerative processes of the central nervous system are an important socially significant problem of modern society. They cause many diseases, such as Alzheimer's disease and cerebral ischemia, which significantly reduce the quality of human life ...
Alexey S. Chiriapkin +2 more
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Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization
Molecules, 2018 Cis/trans isomerization of amide bonds is a key step in a wide range of biological and synthetic processes. Occurring through C-N amide bond rotation, it also coincides with the activation of amides in enzymatic hydrolysis.
Balmukund S. Thakkar +2 more
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