Results 11 to 20 of about 18,468 (228)
The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship
Molecules, 2020 The translocator protein (TSPO, 18 kDa) plays an important role in the synthesis of neurosteroids by promoting the transport of cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step in neurosteroidogenesis ...
Tatiana A. Gudasheva +6 more
doaj +1 more source
Self-Assembled Short Peptide Nanostructures: ‘’Dipeptides’’
MANAS: Journal of Engineering, 2023 Dipeptides are short peptide molecules formed by the peptide bond between two amino acids, and they play significant roles in various biological processes (such as protein synthesis, nutrient absorption, cellular signaling, immune response).
Mehmet Odabaşı +4 more
doaj +1 more source
Molecules, 2021 Several derivatives containing morpholine/piperidine, anilines, and dipeptides as pending moieties were prepared using s-triazine as a scaffold. These compounds were evaluated for their anticancer activity against two human breast cancer cell lines (MCF ...
Azizah M. Malebari +8 more
doaj +1 more source
Frontiers in Plant Science, 2021 As autotrophic organisms, plants capture light energy to convert carbon dioxide into ATP, nicotinamide adenine dinucleotide phosphate (NADPH), and sugars, which are essential for the biosynthesis of building blocks, storage, and growth.
Maria Juliana Calderan-Rodrigues +10 more
doaj +1 more source
Feedback Regulation of Cathepsin C by the Propeptide Dipeptides of Granzymes A and B
Acta Chimica Slovenica, 2019 Granzymes A and B are activated by proteolytic removal of their N-terminal dipeptides by cathepsin C (dipeptidyl-peptidase I). However, the possible physiological role of the cleaved dipeptides Glu-Lys and Gly-Glu is not yet understood.
Janja Božič, Iztok Dolenc
doaj +1 more source
The Synthesis of (2R)-Aziridine-2-carboxylic Acid Containing Dipeptides
Acta Chimica Slovenica, 2022 Optimized conditions for the synthesis of fully deprotected (2R)-aziridine containing dipeptides are described. Preparation of fully protected N- and C- terminal aziridine containing dipeptides was found to be straightforward and high yielding for the ...
Samo Kuzmič, Martina Hrast, Rok Frlan
doaj +1 more source
Dipeptide Absorption in Cystinuria [PDF]
Clinical Science, 1970 Absorption of a dipeptide and its constituent amino-acids has been studied by a perfusion technique in a patient with cystinuria and in a normal subject. Though the cystinuric patient was unable to absorb the dibasic amino-acid lysine in its free form, the dipeptide glycyl-L-lysine was well absorbed.
M D, Hellier +2 more
openaire +3 more sources
Molecules, 2023 Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben +6 more
doaj +1 more source
Dipeptide absorption in man [PDF]
Gut, 1972 A quantitative perfusion method has been used to study intestinal absorption of two dipeptides—glycyl-glycine and glycyl- l -alanine—in normal subjects. In each case, the constituent amino acids were absorbed faster when presented as dipeptides than as free amino acids, suggesting intact ...
M D, Hellier +3 more
openaire +2 more sources
Nearest-Neighbor Interactions and Their Influence on the Structural Aspects of Dipeptides
Biochemistry Research International, 2013 In this theoretical study, the role of the side chain moiety of C-terminal residue in influencing the structural and molecular properties of dipeptides is analyzed by considering a series of seven dipeptides.
Gunajyoti Das, Shilpi Mandal
doaj +1 more source