Results 91 to 100 of about 63,745 (188)

A Stepwise [4 + 3] Cycloaddition Reaction of the 1,3-Diphenyl-2-azaallyl Anion [PDF]

, 1993
The 1,3-diphenyl-2-azaallyl anion (1) undergoes [3 + 2] cycloaddition reactions with the s-cis-fixed 1,3-dienes 8-11. In contrast, 1,1,2,2,3,3-hexamethyl-4,5-bis(methylene)cyclopentane (7) reacts with 1 to give the [4 + 3] cycloadduct 13 and the linear 1,
Mayr, Herbert, Heigl, Ulrich W., Baran, Janusz   +2 more
core   +1 more source

Nano- and Microstructured Delivery Systems Containing Diphenyl Diselenide: A Scoping Review

Diphenyl diselenide, an organoselenium compound widely investigated in experimental models, exhibits several pharmacological properties, including antioxidant, anti-inflammatory, neuroprotective, antimicrobial, and antitumor activities.
Roberto Pontarolo, Fabricio Costa Fanhani, Ana Clara Rodrigues de Freitas, Marcel Henrique Marcondes Sari, wellington martins de carvalho ragassi, Luana Mota Ferreira, Eric Luiz Domingos   +6 more
core   +1 more source

Protective effects of novel organic selenium compounds against oxidative stress in the nematode Caenorhabditis elegans

Toxicology Reports, 2015
Organic selenium compounds possess numerous biological properties, including antioxidant activity. Yet, the high toxicity of some of them, such as diphenyl diselenide (DPDS), is a limiting factor in their current usage.
Sílvio Terra Stefanello, Priscila Gubert, Bruna Puntel, Caren Rigon Mizdal, Marli Matiko Anraku de Campos, Syed M. Salman, Luciano Dornelles, Daiana Silva Avila, Michael Aschner, Félix Alexandre Antunes Soares   +9 more
doaj   +1 more source

Indium(I) iodide-mediated cleavage of diphenyl diselenide. An efficient one-pot procedure for the synthesis of unsymmetrical diorganyl selenides

, 2003
A simple and efficient procedure has been developed for the synthesis of unsymmetrical diorganyl selenides through a one-pot indium(I) iodide-mediated reaction of alkyl halide and diphenyl diselenide in methylene chloride at room ...
Ranu, Brindaban C., Mandal, Tanmay, Samanta, Sampak   +2 more
core   +1 more source

Synthesis and Biological Evaluation of 2-Picolylamide-Based Diselenides with Non-Bonded Interactions

Molecules, 2015
In this paper, we report the synthesis and biological evaluation of picolylamide-based diselenides with the aim of developing a new series of diselenides with O···Se non-bonded interactions.
Jamal Rafique, Sumbal Saba, Rômulo Faria Santos Canto, Tiago Elias Allievi Frizon, Waseem Hassan, Emily Pansera Waczuk, Maryam Jan, Davi Fernando Back, João Batista Teixeira Da Rocha, Antonio Luiz Braga   +9 more
doaj   +1 more source

Selenoprotein L-inspired nano-vesicular peroxidase mimics based on amphiphilic diselenides [PDF]

, 2018
In this study, we developed selenoprotein L-inspired nano-vesicular peroxidase mimics based on amphiphilic diselenides. Selenocystine (SeCyst) was used as the starting material for the synthesis of four liposomal membrane-compatible diselenide ...
Fuchigami, Takeshi, Yui Emaya, Mamoru Haratake, Sakura Yoshida, Haratake, Mamoru, Nakayama, Morio, Takeshi Fuchigami, Emaya, Yui, Wataru Uehara, Yoshida, Sakura, Morio Nakayama, Uehara, Wataru   +11 more
core   +1 more source

Diphenyl diselenide and its interaction with antifungals against Aspergillus spp

, 2020
Given the few antifungal classes available to treat aspergillosis, this study aimed to evaluate the in vitro antifungal activity of diphenyl diselenide (PhSe)2 alone and in combination with classical antifungals against Aspergillus spp., and its in vivo ...
Martinez, Marife, Stevens, David A, Sass, Gabriele, Melo, Aryse Martins, Nogueira, Cristina Wayne, Trapaga, Mariana, Poester, Vanice Rodrigues, Xavier, Melissa Orzechowski, Zeni, Gilson   +8 more
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Activity of Diphenyl diselenide against Aspergillus isolates

, 2020
Organoselenium compounds have been showing promising antimicrobial activity against bacteria and some fungal species. Among these compounds, diphenyl diselenide (PhSe)2 is a simple and chemically stable molecule with proven low toxicity to animal hosts.
Roca, Beatriz, Stevens, David A., Munhoz, Lívia, Melo, Aryse Martins, Trápaga, Mariana, Klafke, Gabriel Baracy, Poester, Vanice Rodrigues, Xavier, Melissa Orzechowski, Sabino, Raquel   +8 more
core  

Diphenyl Diselenide and SARS-CoV-2: in silico Exploration of the Mechanisms of Inhibition of Main Protease (M^pro) and Papain-like Protease (PL^pro). [PDF]

J Chem Inf Model, 2023
Omage FB, Madabeni A, Tucci AR, Nogara PA, Bortoli M, Rosa ADS, Neuza Dos Santos Ferreira V, Teixeira Rocha JB, Miranda MD, Orian L.   +9 more
europepmc   +1 more source

Diphenyl Diselenide Alleviates Tert-Butyl Hydrogen Peroxide-Induced Oxidative Stress and Lipopolysaccharide-Induced Inflammation in Rat Glomerular Mesangial Cells. [PDF]

Int J Mol Sci, 2022
Wang X, Huan Y, Liu S, Li C, Cao H, Lei L, Liu Q, Ji W, Sun S, Huang K, Zhou J, Shen Z.   +11 more
europepmc   +1 more source