Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Journal of Lipid Research, 2016 Oligosaccharyl phosphates (OSPs) are hydrolyzed from oligosaccharide-diphosphodolichol (DLO) during protein N-glycosylation by an uncharacterized process.
Ahmad Massarweh +8 more
doaj
Ribulose 1,5-Diphosphate Carboxylase Activity in Relation to Photosynthesis by Intact Leaves And Isolated Chloroplasts. [PDF]
, 1959 Robert M. Smillie, R. Clinton Fuller
openalex +1 more source
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
METABOLISM OF FRUCTOSE-1,6-DIPHOSPHATE AND ACETATE IN ACETOBACTER SUBOXYDANS [PDF]
, 1957 Paul A. Kitos +2 more
openalex +1 more source
Polyisoprenyl Diphosphate Phosphatase 1 Remodels Cellular Presqualene Diphosphate
The FASEB Journal, 2008 Previous work established that presqualene diphosphate (PSDP), a polyisoprenyl diphosphate (PIPP) that blocks pivotal intracellular signals in PMN, is rapidly converted to its monophosphate form (PSMP) upon cell activation. PIPP phosphatase 1 (PDP1) is the first PSDP phosphatase.
Bruce D. Levy +2 more
openaire +2 more sources
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
Chemistry &Biodiversity, EarlyView.ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos +8 more
wiley +1 more source
The Effect of Tetra-sodium 2-Methyl-1: 4-Naphthohydroquinone Diphosphate (Synkayvite) on a Variety of Malignant Tumours in Experimental Animals [PDF]
, 1950 Alfred Gellhorn, Tersa Gagliano
openalex +1 more source
Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential
Chemistry &Biodiversity, EarlyView.Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira +9 more
wiley +1 more source
Spectroscopic effects of adenosine diphosphate upon the respiratory pigments of rat-heart-muscle sarcosomes [PDF]
, 1958 B. Chance, Margareta Baltscheffsky
openalex +1 more source