Results 131 to 140 of about 21,027 (334)

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, EarlyView.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source

Conversion from Farnesyl Diphosphate Synthase to Geranylgeranyl Diphosphate Synthase by Random Chemical Mutagenesis [PDF]

, 1996
Shin‐ichi Ohnuma, T Nakazawa, Hisashi Hemmi, Anna-Maria Hallberg, Tanetoshi Koyama, Kyozo Ogura, Tokuzo Nishino   +6 more
openalex   +1 more source

Об условиях синтеза кобальт(II) дифосфата гексагидрата [PDF]

, 2009
Визначено умови одержання та взаємодією у системі СоSO₄ – K₄P₂O₇ – H₂O с интезовано аморфний Со₂Р₂О₇·5Н₂О і кристалічний Со₂Р₂О₇·6Н₂О кобальт(ІІ) дифосфати.
Антрапцева, Н. М., Ткачева, Н. В.   +1 more
core  

ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay

Cytoskeleton, EarlyView.
ABSTRACT Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternative splicing of a neural‐specific microexon in DAAM1 in modulating actin's role in synaptic processes.
Patryk Poliński, Marta Miret Cuesta, Manuel Irimia   +2 more
wiley   +1 more source

Epilepsy Phenotypic Spectrum of NUS1‐Related Disorder: A Case Series

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Epilepsy with myoclonic and atonic seizures (EMAtS), also known as Doose syndrome, accounts for 1%–2% of childhood epilepsies, and various genes have been implicated in causing this epilepsy syndrome. NUS1 encodes for Nogo‐B receptor (NgBR), which stabilizes the dehydrodolichyl‐diphosphate synthase complex in the endoplasmic ...
Saumel Ahmadi, Natalie Fulton, Michael Morrissey, Rebekah Landre, Stuart Tomko, Fumihiko Urano, Réjean M Guerriero   +6 more
wiley   +1 more source

Identification and expression analysis of NUDIX gene family in Rosa chinensis ‘Old Blush’

浙江大学学报. 农业与生命科学版
To explore the function and potential application of NUDIX (nucleoside diphosphates linked to other moieties X) gene family in Rosa chinensis ‘Old Blush’, 41 NUDIX gene family members of Rosa chinensis ‘Old Blush’ were identified using bioinformatics ...
FANG Huiyi, LIANG Yuwei, LI Xinyuan, Sun Fuhui, BI Bo, ZHANG Liangsheng   +5 more
doaj   +1 more source

Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte [PDF]

, 1990
Ames, Anastassiades, Angyal, Ballou, Breslow, Butlerow, Bürgi, Bürgi, Castells, Decker, Denmark, Drenkard, Eschenmoser, Eschenmoser, Evans, Ferris, Fischer, Fischer, Fischer, Fischer, Fluharty, Guerrier-Takada, Heathcock, Heathcock, Huskey, IUPAC/IUB, King-Morris, Ksander, Langenbeck, Langenbeck, Loew, Lyengar, Masamune, Masamune, Matsumoto, Miller, Miller, Miller, Mitchell, Mizuno, Orgel, Oro, Pfeil, Pfeil, Racker, Richard, Ruckert, Seebach, Shapiro, Shapiro, Shigemasa, Shigemasa, Shigemasa, Socha, Wagner, Warren, Weiss, Weissbuch, Westheimer, Zaug, Zimmermann   +60 more
core   +1 more source

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

Clinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park, Jae‐Hwan Lee, Jin‐Ok Jeong, Diana A. Gorog, Udaya S. Tantry, Byeong‐Keuk Kim, Hyung Joon Joo, Kiyuk Chang, Jin‐Yong Hwang, Young Bin Song, Sung Gyun Ahn, Jung‐Won Suh, Woong Gil Choi, Jung Rae Cho, Jeehoon Kang, Sang Yeub Lee, Hyo‐Soo Kim, Moo Hyun Kim, Do‐Sun Lim, Eun‐Seok Shin, Paul A. Gurbel, Young‐Hoon Jeong, on behalf of the PTRG‐DES Consortium Investigators   +22 more
wiley   +1 more source

Quantitation of hydroxylamine sensitive mono(adenosine diphosphate ribose) residues in different hepatic tissues [PDF]

, 1975
Peter Stone, Helmuth Hilz, Helgard Lengyel   +2 more
openalex   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source