Results 1 to 10 of about 7,343 (255)

Spondylosis in Horses: Clinical Features, Diagnostic Imaging Findings, Treatment and Outcome in 13 Horses

Veterinary Medicine and Science, Volume 11, Issue 2, March 2025.
The aim of this study is to describe for the first time clinical signs, treatment and long‐term outcomes of horses diagnosed with thoracic spondylosis. Of the 13 horses that met the inclusion criteria, four were able to continue their athletic careers with good results, after treatment and rehabilitation. ABSTRACT Background Back pain is a debilitating
Claudia de Secondi, Federica Cantatore, Marco Marcatili, Marianna Biggi, Jonathan Withers, Donatella de Zani, Davide Zani   +6 more
wiley   +1 more source

Interaction between Kupffer cells and platelets in the early period of hepatic ischemia–reperfusion injury—An in vivo study [PDF]

, 2012
journal ...
FUKUNAGA Kiyoshi, KONDO Tadashi, Murata Soichiro, Nakano Yoritaka, OHKOHCHI Nobuhiro, Pak Sugiru, TAMURA Takafumi   +6 more
core   +1 more source

Frailty in heart failure according to the presence or absence of wild‐type transthyretin cardiac amyloidosis

ESC Heart Failure, Volume 12, Issue 1, Page 281-289, February 2025.
Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt CA) is a common, underdiagnosed cause of heart failure (HF) in the elderly. Concurrent extracardiac amyloid infiltration might be responsible for a specific frailty phenotype. This study aims to compare the prevalence and characteristics of frailty parameters in HF patients, with or ...
Amaury Broussier, Marie Paugam, Nina Liu, Silvia Oghina, Mounira Kharoubi, Charlotte Lafont, Amira Zaroui, Arnault Galat, Luc Hittinger, Emmanuel Teiger, Jean Philippe David, Sylvie Bastuji‐Garin, Thibaud Damy   +12 more
wiley   +1 more source

Pharmacokinetics of Pamidronate in Patients With Bone Metastases [PDF]

, 2017
Background: Pamidronate is a secondgeneration bisphosphonate used in the treatment of tumor-induced hypercalcemia and in the management of bone metastases from breast cancer, myeloma, or prostate cancer.
Bauer, J., Burckhardt, P., Flesch, G., Ford, J. M., Hauffe, S., Hess, U., Leyvraz, S.   +6 more
core  

Metal Pyrazolyl‐Diphosphonate Pillared Materials as Heterogeneous Catalysts in the Mukaiyama‐Type Aerobic Olefin Epoxidation

Chemistry – A European Journal, Volume 31, Issue 6, January 27, 2025.
The coordination of the organic PZDP linker to alkaline earth or transition metals yields 2D‐pillared metal phosphonate frameworks under solvothermal or hydrothermal conditions. The structures of the materials are determined and the catalytic performance of Co‐PZDP is tested in the Mukaiyama olefin epoxidation, achieving high yields of the ...
Nikolaos S. Giakoumakis, Elpiniki Chachlaki, Duane Choquesillo‐Lazarte, Konstantinos D. Demadis   +3 more
wiley   +1 more source

Use of Bone Scanning and Skeletal Radiography in the Diagnosis of Bone Metastasis [PDF]

, 1975
The radionuclide bone scan is becoming increasingly useful for evaluating a wide variety of bone and joint disorders. However, the commonest application is still the detection of skeletal metastases in the patient with known or suspected neoplastic ...
Hoffer, Paul B., Mall, Jay C.
core   +1 more source

The role of bisphosphonates in breast cancer: Development of bisphosphonates [PDF]

, 2001
Bisphosphonates are synthetic compounds characterized by a P–C–P group, and are thus analogs of inorganic pyrophosphate. They are used in medicine mainly to inhibit bone resorption in diseases like osteoporosis, Paget's disease and tumor bone disease ...
A Jung, A Jung, A Sasaki, AA Reszka, AB Gasser, CM Shipman, DE Hughes, E van Beek, E van Beek, G van der Pluijm, GR Mundy, H Fleisch, H Fleisch, H Fleisch, H Fleisch, H Fleisch, Herbert Fleisch, JC Frith, JD Bergstrom, JE Dunford, JE Fisher, M Menschutkin, MD Francis, MJ Rogers, P Masarachia, R Schenk, RGG Russell, RR Martodam, S Boissier, SP Luckman, SP Luckman   +30 more
core   +2 more sources

Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling

Clinical Pharmacology &Therapeutics, Volume 117, Issue 1, Page 261-269, January 2025.
NI006 (aka ALXN2220) is a therapeutic antibody candidate in phase III clinical development for the depletion of amyloid transthyretin (ATTR) in patients with ATTR cardiomyopathy, an infiltrative cardiomyopathy leading to increased left ventricular wall thickness (LVWT).
Aubin Michalon, Lionel Renaud, Matthias Machacek, Cédric Cortijo, Chandrasekhar Udata, Michele F. Mercuri, Fabian Buller, Christoph Hock, Roger M. Nitsch, Peter C. Kahr, Jan Grimm   +10 more
wiley   +1 more source

In vitro and in vivo evaluation of superparamagnetic iron oxide nanoparticles coated by bisphosphonates: the effects of electrical charge and molecule length. [PDF]

, 2013
Physicochemical coating properties are often considered to be determining factors for in vivo characteristics of superparamagnetic iron oxide nanoparticles, used as contrast agent in Magnetic Resonance Imaging (MRI). To investigate the electrical charge (
A. Karimi, B. Denizot, C. Passirani-Malleret, F. Hindré, J. Roux, J.J. Le Jeune, P. Legras   +6 more
core   +3 more sources

A Two‐Stage CNN‐Based Method for Enhanced Metastasis Segmentation in SPECT Bone Scans

International Journal of Intelligent Systems, Volume 2025, Issue 1, 2025.
Accurate segmentation of metastatic lesions is crucial for improving the quality of patient care, particularly in the context of bone scans. However, existing automated methods, which are predominantly data‐driven, exhibit limited performance and lack interpretability.
Yang He, Qiang Lin, Zhengxing Man, Yongchun Cao, Xianwu Zeng, Xiaodi Huang, Vittorio Memmolo   +6 more
wiley   +1 more source