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Diagnostic Accuracy of PET with Different Radiotracers versus Bone Scintigraphy for Detecting Bone Metastases of Breast Cancer: A Systematic Review and a Meta-Analysis [PDF]

open access: yesJournal of Imaging, 2023
Due to the importance of correct and timely diagnosis of bone metastases in advanced breast cancer (BrC), we performed a meta-analysis evaluating the diagnostic accuracy of [18F]FDG, or Na[18F]F PET, PET(/CT), and (/MRI) versus [99mTc]Tc-diphosphonates ...
Maryam Zamanian   +2 more
doaj   +2 more sources

Incidental finding of bone tracer accumulation in gastrointestinal stromal tumor: Two case reports [PDF]

open access: yesRadiology Case Reports
Bone scintigraphy with technetium-labelled diphosphonates is widely used for evaluating skeletal pathology. However, extra-osseous uptake may also be encountered and can indicate underlying neoplastic processes.
Gary Ka Wai Chan, MBChB   +3 more
doaj   +2 more sources

Comparison of the Effectiveness and Hypocalcemia Risk of Antiresorptive Agents in Patients with Hypercalcemia of Malignancy [PDF]

open access: yesEndocrinology and Metabolism
Background Hypercalcemia of malignancy (HCM), a major metabolic complication of cancer, is often managed with bisphosphonates (BP) and, increasingly, with denosumab.
Sung Hye Kong   +6 more
doaj   +2 more sources

Review and Update of the Risk Factors and Prevention of Antiresorptive-Related Osteonecrosis of the Jaw [PDF]

open access: yesEndocrinology and Metabolism, 2021
Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but serious adverse event of bisphosphonate or denosumab administration; it is associated with severe pain and a deteriorated quality of life.
Ha Young Kim
doaj   +1 more source

Long-Term Treatment of Postmenopausal Osteoporosis [PDF]

open access: yesEndocrinology and Metabolism, 2021
Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate ...
Jacques P. Brown
doaj   +1 more source

Synthesis of Four Enantiomers of (1-Amino-3-Hydroxypropane-1,3-Diyl)Diphosphonic Acid as Diphosphonate Analogues of 4-Hydroxyglutamic Acid

open access: yesMolecules, 2022
All the enantiomers of (1-amino-3-hydroxypropane-1,3-diyl)diphosphonic acid, newly design phosphonate analogues of 4-hydroxyglutamic acids, were obtained.
Liwia Lebelt   +2 more
doaj   +1 more source

Effects of red and infrared laser on post extraction socket repair in rats subjected to alendronate therapy [PDF]

open access: yesBrazilian Oral Research, 2023
This study evaluated the effect of photobiomodulation therapy (PBMT) with a red or infrared laser on the repair of post extraction sockets in rats administered alendronate (ALN).
Fernanda Castanheira GONÇALVES   +4 more
doaj   +1 more source

Can bone turnover markers help to define the suitability and duration of bisphosphonate drug holidays?

open access: yesDrugs in Context, 2020
Background: On stopping bisphosphonate treatment, bone resorption may increase before evidence of a decrease in bone density. Offset of bisphosphonate effect may therefore be monitored by measuring C-terminal telopeptide (CTX) following long-term ...
Louise Statham   +2 more
doaj   +1 more source

Osteonecrosis of the jaw as a serious adverse effect of bisphosphonate therapy and its indistinct etiopathogenesis [PDF]

open access: yesVojnosanitetski Pregled, 2014
nema
Gavrić Miodrag   +6 more
doaj   +1 more source

Obesity influences the development of bisphosphonate-induced osteonecrosis in Wistar rats [PDF]

open access: yesJournal of Applied Oral Science, 2023
Medication-related osteonecrosis of the jaw (MRONJ) is characterized by bone exposure for more than eight weeks in patients who have used or been treated with antiresorptive or antiangiogenic drugs, without a history of radiation therapy or metastatic ...
Wilson José de Miranda LIMA   +7 more
doaj   +1 more source

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