Results 21 to 30 of about 5,826 (213)
Patients with prostate cancer (PCa) on androgen-deprivation therapy (ADT) are at high risk of osteoporosis and fragility fractures. We aimed to provide some practical insights into the delivery of optimal bone health care for PCa patients, particularly
Enrique Casado+5 more
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Objectives: Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats ...
Felipe M. Silveira+3 more
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Renal secretion of diphosphonates in rats
Diphosphonates, characterized by a P--C--P bond, are relatively new experimental drugs used for the treatment of myositis ossificans, dental calculus, nephrolithiasis and Paget's disease. These compounds are not metabolized and the fraction which is not taken up by the skeleton is excreted unchanged in the urine.
Herbert Fleisch+2 more
openaire +3 more sources
Severe congestive heart failure in elderly patient with Paget’s disease
Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj +1 more source
In conditions of 120-daily bedrest changes of a metabolism of the calcium, the functions of a bone directed on preservation at a necessary level of a bone material at the maximal economy level in these conditions were studied.
O I ORLOV
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Rhenium Radioisotopes for Medicine, a Focus on Production and Applications
In recent decades, the use of alpha; pure beta; or beta/gamma emitters in oncology, endocrinology, and interventional cardiology rheumatology, has proved to be an important alternative to the most common therapeutic regimens. Among radionuclides used for
Licia Uccelli+9 more
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Diphosphonates in the treatment of osteoporosis
Etidronate disodium has been shown to increase bone density and decrease fracture rates, but it may have more important applications in the prevention of bone loss.
openaire +3 more sources
Pamidronato dissódico (APD) no tratamento das metástases ósseas.
Diphosphonates are potent inhibitors of bone resorption, they have been evaluated in several clinical trials for bone metastases. We performed a clinical study to evaluate the therapeutic effect of Disodium Pamidronate over pain and radiologic evolution ...
L Costa, C Moreira, E B da Costa
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Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature [PDF]
There has been a conscious effort to address osteoporosis in the aging population. As bisphosphonate and intermittent parathyroid hormone (PTH) therapy become more widely prescribed to treat osteoporosis, it is important to understand their effects on ...
Michael A. Stone+9 more
doaj +1 more source
CTHRC1 promotes bone metastasis in prostate cancer
What's New? The mechanisms driving bone metastasis in prostate cancer are still unclear, and predicting markers have not yet been identified. Based on the biological characterization of prostate cancer cell lines and integrated data analysis of clinical samples, the authors identified CTHRC1 as a candidate gene regulating prostate cancer bone ...
Yuichiro Sawada+18 more
wiley +1 more source