Effectiveness and safety of pamidronate treatment in nonambulatory children with low bone mineral density [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose Nonambulatory pediatric patients may have low bone mineral density (BMD) and increased risk of pathologic fractures. Though bisphosphonate therapy is the mainstream medical intervention in these children, clinical data regarding this treatment ...
Myeongseob Lee +7 more
doaj +1 more source
Differential sensitivity of membrane-associated pyrophosphatases to inhibition by diphosphonates and fluoride delineates two classes of enzyme [PDF]
, 1993 1,1-Diphosphonate analogs of pyrophosphate, containing an amino or a hydroxyl group on the bridge carbon atom, are potent inhibitors of the H+-translocating pyrophosphatases of chromatophores prepared from the bacterium Rhodospirillum rubrum and vacuolar
Bakuleva, Natalia P. +5 more
core +1 more source
Strontium Ranelate Elevates Expression of Heme Oxygenase-1 and Decreases Alveolar Bone Loss in Rats
eJournal of Oral Maxillofacial Research, 2018 Objectives: The purpose of this study was to determine the effects of strontium ranelate on ligature-induced periodontitis in rats and assess the putative involvement of heme oxygenase-1 (HO-1) pathway in these effects.
Ricardo Basto Souza +6 more
doaj +1 more source
The role of bisphosphonates in breast cancer: Development of bisphosphonates [PDF]
, 2001 Bisphosphonates are synthetic compounds characterized by a P–C–P group, and are thus analogs of inorganic pyrophosphate. They are used in medicine mainly to inhibit bone resorption in diseases like osteoporosis, Paget's disease and tumor bone disease ...
A Jung +30 more
core +2 more sources
Treatment of bone metastases from breast cancer with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD). [PDF]
, 1988 Twenty-eight patients with progressive symptomatic bone metastases from breast cancer received (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD) 30 mg in 500 ml of 0.9% saline infused over 2 h every 14 days.
Coleman, R. E. +4 more
core +2 more sources
, 2014 Eight new transition metal diphosphonates, namely, [Mn(H2L)(H2O)2][(H2O)2] (1), [Co(H2O)6][H2L][(H2O)2] (2), [Co(H2O)6][(H3L)2][(H2O)2] (3), [Ni(H2O)6][H2L][(H2O)2] (4), [Cu(H2L)][(H2O)2] (5), [Zn(H2O)6][(H3L)2][(H2O)2] (6), [Zn(H2L)(H2O)2] (7) and [Cd ...
Sifu Tang +4 more
semanticscholar +1 more source
BISPHOSPHONATES RELATED OSTEONECROSIS OF THE JAW IN CANCER PATIENTS – EPIDEMIOLOGICAL STUDY
Romanian Journal of Oral Rehabilitation, 2022 Aim of the study Medication related osteonecrosis of the jaw (MRONJ) is a severe drug adverse effect, often being diagnosed in an advanced stage. The aim of this epidemiological study was to determine the frequency of MRONJ in cancer patients from ...
George Adrian Ciobanu +8 more
doaj
Chronic intoxication by ethane-1-hydroxy-1,1-diphosphonate (EHDP) in a child with myositis ossificans progressiva. [PDF]
, 1993 Chronic intoxication by ethane-1-hydroxy-1,1-diphosphonate (EHDP) in a child with myositis ossificans progressiva.
Beluffi G +4 more
core +1 more source
Photoinduced Absorption Spectra of Halogen-Bridged Binuclear Metal Complexes: Possible Contrast between R_4_[Pt_2_(P_2_O_5_H_2_)_4_X]nH_2_O and Pt_2_(CH_3_CS_2_)_4_I [PDF]
, 2004 The optical conductivity of photogenerated solitons in quasi-one-dimensional halogen-bridged binuclear metal (MMX) complexes is investigated with particular emphasis on a comparison between the two family compounds R_4_[Pt_2_(P_2_O_5_H_2_)_4_X]nH_2_O (X=Cl,Br,I;R=NH_4_,Na,K,...; pop=diphosphonate=P_2_O_5_H_2_^2-^) and Pt_2_(dta)_4_I (dta=dithioacetate ...
arxiv +1 more source
Severe congestive heart failure in elderly patient with Paget’s disease
Geriatric Care, 2017 Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj +1 more source