Results 51 to 60 of about 92,948 (222)
Advanced Science, EarlyView.This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun +23 more
wiley +1 more source
Pediatric Rheumatology Online Journal, 2021 Background Immunosuppressive drugs, incomplete vaccine coverage, immune system dysregulation might be factors of a low level of anti-vaccine antibodies in JIA patients. The study aimed to evaluate vaccine coverage, post-vaccine immunity, and risk factors
Mikhail M. Kostik +4 more
doaj +1 more source
Paediatrica IndonesianaBackground Diphtheria can be effectively prevented by adequate immunization. A combined vaccine against diphtheria toxoid, pertussis, and tetanus toxoid (DPT) is currently used in routine pediatric immunizations.
Theresia Santi +8 more
doaj +1 more source
Breaking barriers: Smart vaccine platforms for cancer immunomodulation
Cancer Communications, EarlyView.Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari +11 more
wiley +1 more source
Is Diphtheria Booster Vaccination Still Necessary in Turkey?
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2018 Introduction: Diphtheria is a serious disease that can be prevented by vaccination. The aim of the study was to determine immunity against diphtheria and the necessity of booster doses in the adult population.Materials and Methods: Serum antibody levels ...
Sule Eren CAKAR +5 more
doaj +1 more source
Immune cell dynamics in heart failure: implicated mechanisms and therapeutic targets
ESC Heart Failure, EarlyView.Abstract The relationship between heart failure (HF) and immune activation has garnered significant interest. Studies highlight the critical role of inflammation in HF, affecting cardiac structure and function. Despite promising anti‐inflammatory therapies, clinical trials have faced challenges, indicating an incomplete understanding of immune ...
Gen Li, Wu He, Dao Wen Wang
wiley +1 more source
International Journal of Infectious Diseases, 2020 Objective: To determine the seroprevalence of antibodies against of diphtheria, tetanus, and pertussis among Thai adolescents. Methods: A cross-sectional study was conducted among Thai adolescents aged 11–20 years who had completed five doses of ...
Pimpika Hanvatananukul +7 more
doaj
Nanomaterials for acute myeloid leukemia therapy: Current progress and future perspectives
Interdisciplinary Medicine, EarlyView.Infographics of this review introducing the current treatment strategies, types of nanomaterials, and their advantages in AML treatment (Created with BioRender.com, a license purchased, accessed on March 26, 2024). Abstract Acute myeloid leukemia (AML) is a highly aggressive hematologic malignancy characterized by poor prognosis, high relapse rates ...
Jiarui Zhao +8 more
wiley +1 more source