Recurrent diphtheria outbreaks in Nigeria: A review of the underlying factors and remedies [PDF]
Introduction The introduction of the diphtheria−tetanus−pertussis (DTP) vaccine into childhood immunization programs resulted in its widespread elimination in high‐income countries. However, Nigeria is currently experiencing an outbreak.
Nasir Abdulrasheed+10 more
doaj +4 more sources
Seroprevalence of IgG antibodies against diphtheria antitoxin among migrant workers in Singapore, 2016–2019 [PDF]
Background Since the last local case of diphtheria in 1992, there had not been any case in Singapore until an autochthonous case was reported in 2017.
Li Wei Ang+10 more
doaj +3 more sources
Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin [PDF]
Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin+5 more
doaj +3 more sources
Diphtheria Antitoxin Administration, Outcomes, and Safety: Response to a Diphtheria Outbreak in Cox's Bazar, Bangladesh. [PDF]
Background Diphtheria has re-emerged over the past several years. There is a paucity of data on the administration and safety of diphtheria antitoxin (DAT), the standard treatment for diphtheria.
Eisenberg N+9 more
europepmc +2 more sources
The re-emergence of diphtheria in Nigeria: Descriptive assessment of the post-COVID-19 crisis management. [PDF]
Health Science Reports, Volume 6, Issue 11, November 2023.
Ogunniyi TJ+3 more
europepmc +2 more sources
Investigating Alternative Container Formats for Lyophilization of Biological Materials Using Diphtheria Antitoxin Monoclonal Antibody as a Model Molecule [PDF]
When preparing biological reference materials, the stability of the lyophilized product is critical for long-term storage, particularly in order to meet WHO International Standards, which are not assigned expiry dates but are expected to be in use for ...
Kiran P. Malik+5 more
doaj +2 more sources
UNTOWARD RESULTS FROM DIPHTHERIA ANTITOXIN. [PDF]
The Journal, Jan. 25, 1908, published a letter from me asking for reports of cases in which the injection of diphtheria antitoxin had been followed by alarming symptoms or death, especially noting whether there was any history of asthma in the case.
HERBERT F. GILLETTE
openalex +2 more sources
Effect of acupuncture therapy on vaccine-induced immune response in d-galactose-induced aging rats [PDF]
Objective: This study aimed to explore whether acupuncture and moxibustion can enhance the immune response by increasing the expression of the endogenous adjuvant HSP70 mRNA.
Jia Li+4 more
doaj +2 more sources
Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study [PDF]
Background Despite recurrent outbreaks of diphtheria in Nigeria, there is a lack of in-depth analysis of hospitalization outcomes. Herein, we describe the sociodemographic, clinical, and laboratory features associated with hospitalization outcomes ...
Abdurrazzaq Alege+7 more
doaj +2 more sources
A population-level analysis of armed conflict and diphtheria at the subnational level in the WHO African Region 2017–2024 [PDF]
Background Diphtheria has been re-emerging around the world at alarming rates, raising concerns about emergency preparedness, especially when global supplies of life-saving diphtheria antitoxin are insufficient.
Tierney O’Sullivan, Lindsay T. Keegan
doaj +2 more sources