Results 91 to 100 of about 362,065 (266)
Advanced Science, Volume 13, Issue 1, 5 January 2026.Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
The MicrobeBackground of study: Diphtheria, caused by Corynebacterium diphtheriae, is still a major global health concern, especially in resource-limited settings.
Adedoyin John-Joy Owolade +7 more
doaj +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.Puerarin targets mitochondrial MIC19 in tumor‐infiltrating Tregs, impairing their immunosuppressive function and enhancing antitumor immunity. This study uncovers the metabolic dependency of tumor‐infiltrating Tregs and highlights a potential metabolic‐targeted immunotherapeutic strategy for liver cancer. Abstract Regulatory T cells (Tregs) are pivotal
Yu Li +10 more
wiley +1 more source
Late Presentation of Post Diphtheritic Myocarditis in a 15-year male
Journal of Nepal Medical Association, 2017 A 15-year old male patient presented to us with dyspnoea for four days. He had a history of fever, pseudo-membranous tonsillitis and cervical adenopathy twenty-five days prior to the presentation.
Kutty Sharada Vinod +3 more
doaj +1 more source
Chemical Engineering &Technology, Volume 49, Issue 1, January 2026.This review presents the state‐of‐the‐art knowledge on vibromixers, which are alternative mixing systems to conventional rotating agitators and mostly used in the biotechnology sector. It critically surveys the working principles of different vibromixer types and their operating conditions, the designs and key geometrical parameters, hydrodynamics and ...
Muhammad Muhammad Gimba +2 more
wiley +1 more source
Characterization of a transgenic mouse model of chronic conditional platelet depletion
Research and Practice in Thrombosis and Haemostasis, 2019 Background Platelets are widely recognized for their role in maintaining hemostasis. Recently, platelets have become appreciated for their varying roles in immunity, neuroprotection, and other physiological processes.
Leah M. Wuescher +2 more
doaj +1 more source
BMC Microbiology, 2012 BackgroundCorynebacterium ulcerans can cause a diphtheria-like illness, especially when the bacterium is lysogenized with a tox gene-carrying bacteriophage that produces diphtheria toxin.
T. Sekizuka +7 more
semanticscholar +1 more source
Cancer, Volume 132, Issue 1, 1 January 2026.Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic neoplasm that expresses CD123, is often observed in the bone marrow (BM), as well as skin, blood, and viscera. Tagraxofusp, a first‐in‐class CD123‐targeted therapy, is the only drug approved to treat BPDCN.
Marina Konopleva +10 more
wiley +1 more source
Evidence that the regulation of diphtheria toxin production is directed at the level of transcription [PDF]
, 1978 J R Murphy, J L Michel, Mingxiang Teng
openalex +1 more source
Efzimfotase Alfa Improves Respiratory Capacity in Muscle Tissue From a Mouse Model of HPP
JIMD Reports, Volume 67, Issue 1, January 2026.ABSTRACT Hypophosphatasia (HPP) is an inherited metabolic disease caused by deficient tissue‐nonspecific alkaline phosphatase (ALP) activity and characterized by skeletal and nonskeletal symptoms, including muscle weakness and fatigue. We hypothesized that mitochondrial respiration is impaired in muscle in HPP, independent of skeletal manifestations ...
Denise Devore +10 more
wiley +1 more source