Results 101 to 110 of about 51,558 (250)
, 1989 Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
Levinsky, Norman G. +1 more
core
Locating a residue in the diphtheria toxin channel
Biophysical Journal, 1992 We are studying structure-function relationships in the Diphtheria Toxin (DT) channel using a combination of site-directed mutagenesis and electrophysiology in artificial lipid bilayers. We made site-directed mutations of charged residues in the toxin's channel-forming B fragment, and after expressing the mutant proteins in Escherichia coli, we ...
Joseph A. Mindell +3 more
openaire +3 more sources
Data in Brief, 2022 Corynebacterium diphtheriae (C. diphtheriae) is the causative agent of diphtheria. The main virulence factor of C. diphtheriae is diphtheria toxin, which is encoded by the tox gene and regulated by the dtxR gene.
Vivi Setiawaty +11 more
doaj
Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
BMC Infectious Diseases, 2018 Background Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation A 55-year old male presented to the emergency room
Sten Skogmar, Johan Tham
doaj +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019 Background and Objectives: Cancer is one of the most deadly diseases in the present age and its conventional therapies have had low success. Toxin therapy of cancer is a new therapeutic approach, which has attracted the attention of pharmaceutical ...
Mohaddeseh Parvand +2 more
doaj
Is Diphtheria Booster Vaccination Still Necessary in Turkey?
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2018 Introduction: Diphtheria is a serious disease that can be prevented by vaccination. The aim of the study was to determine immunity against diphtheria and the necessity of booster doses in the adult population.Materials and Methods: Serum antibody levels ...
Sule Eren CAKAR +5 more
doaj +1 more source
The Bacteriology of Diphtheria, including Sections on the History, Epidemiology, and Pathology of the Disease, the Mortality caused by it, the Toxins and Antitoxins, and the Serum Disease [PDF]
, 1908 George Nuttall +2 more
openalex +1 more source
Diphtheria Toxin and Related Proteins
Journal of Biological Chemistry, 1973 Conditions are described for reassembly in high yield of hybrid diphtheria toxin molecules using Fragment A derived from cross-reacting material 45 and Fragment B from other proteins related to diphtheria toxin.
Tsuyoshi Uchida +2 more
openaire +5 more sources
Heparin-binding EGF-like growth factor: mechanisms of biological activity and potential therapeutic applications [PDF]
The Ukrainian Biochemical JournalThe diphtheria toxin receptor on sensitive mammalian cells is known as the membrane anchored precursor of heparin-binding EGF-like growth factor (HB-EGF).
L. M. Dronko +8 more
doaj +1 more source
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis. [PDF]
J Exp Med, 2023 Robinson KS +13 more
europepmc +1 more source