Results 101 to 110 of about 314,031 (226)
The Dynamic Behavior (Effects) of Impulsive Toxicant Input on a Single-Species Population in a Small Polluted Environment [PDF]
arXiv, 2016 In this paper, we study a single-species population model with pulse toxicant input to a small polluted environment. The intrinsic rate of population is affected by environment and toxin in organisms. The toxin in organisms is influenced by toxin in environment and the food chain. A new mathematical model is derived.
arxiv
Maternal IgE Influence on Fetal and Infant Health
Immunological Reviews, Volume 331, Issue 1, May 2025.ABSTRACT Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE‐mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment.
Jozef Balla +2 more
wiley +1 more source
Sri Lankan Journal of Infectious Diseases, 2011 Diphtheria is a nearly eradicated disease in Sri Lanka. After introduction of EPI vaccination program in 1978 childhood diphtheria has been eradicated.
Rohitha Jayamaha
doaj +1 more source
The receptor-toxin-antibody interaction: Mathematical model and numerical simulation [PDF]
arXiv, 2012 A reaction-diffusion model of receptor-toxin-antibody (RTA) interaction is studied numerically. The protective properties of an antibody against a given toxin are evaluated for a spherical cell placed into a toxin-antibody solution. The selection of parameters for numerical simulation approximately corresponds to the practically relevant values ...
arxiv
Journal of Neuroscience, 2012 We developed a transgenic mouse to permit conditional and selective ablation of hair cells in the adult mouse utricle by inserting the human diphtheria toxin receptor (DTR) gene into the Pou4f3 gene, which encodes a hair cell-specific transcription ...
Justin S. Golub +6 more
semanticscholar +1 more source
Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.Fast‐relaxation viscoelastic hydrogel triggers a metabolic shift in macrophages, favoring oxidative phosphorylation (OXPHOS) over glycolysis via vasodilator‐stimulated phosphoprotein (VASP) / hypoxia‐inducible factor 1 alpha (HIF1α) signaling meditated mechanotransdution, thereby enhancing their capacity to recruit mesenchymal stem cells (MSCs) and ...
Dihao Tao +9 more
wiley +1 more source
A solid approach to biopharmaceutical stabilisation [PDF]
, 2018 Ensilication is a technology we developed that can physically stabilise proteins in silica without use of a pre-formed particle matrix. Stabilisation is done by tailor fitting individual proteins with a silica coat using a modified sol-gel process. Biopharmaceuticals, for example, liquid-formulated vaccines with adjuvants, have poor thermal stability ...
arxiv +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.Staphylococcus aureus (S. aureus) infection induces persistent pain via toxins, leading to CGRP release from TRPV1+ nociceptive nerves. CGRP inhibits chemotactic factor release from CX3CR1+ synovial lining macrophages and suppresses their bactericidal activity. This study highlights neuroimmune interactions in chronic septic arthritis and suggests CGRP
Xinyu Fang +19 more
wiley +1 more source
Late Presentation of Post Diphtheritic Myocarditis in a 15-year male
Journal of Nepal Medical Association, 2017 A 15-year old male patient presented to us with dyspnoea for four days. He had a history of fever, pseudo-membranous tonsillitis and cervical adenopathy twenty-five days prior to the presentation.
Kutty Sharada Vinod +3 more
doaj +1 more source
Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197
Proceedings of the National Academy of Sciences of the United States of America, 2012 CRM197 is an enzymatically inactive and nontoxic form of diphtheria toxin that contains a single amino acid substitution (G52E). Being naturally nontoxic, CRM197 is an ideal carrier protein for conjugate vaccines against encapsulated bacteria and is ...
E. Malito +13 more
semanticscholar +1 more source