Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis [PDF]
Proteins in living cells can be made receptive to bioorthogonal chemistries through metabolic labeling with appropriately designed noncanonical amino acids (ncAAs).
Ngo, John T., Tirrell, David A.
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Diethyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2,2-dicarboxylate
The title compound, C18H22N2O7, was synthesized by the 1,3-dipolar cycloaddition reaction of but-3-en-2-one, diethyl 2-aminomalonate and 2-nitrobenzaldehyde. In the molecule, the pyrrolidine ring possesses an envelope conformation.
Long He
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Recent advances in the synthesis of triazole derivatives [PDF]
Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and those dealing with the medicinal compounds due to its versatile potential to interact with biological systems.
Ahmad, Matloob +6 more
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Rational Perturbation of the Fluorescence Quantum Yield in Emission‐Tunable and Predictable Fluorophores (Seoul‐Fluors) by a Facile Synthetic Method Involving C—H Activation† [PDF]
Fluorescence imaging enables the uniquely sensitive observation of functional‐ and molecular‐recognition events in living cells. However, only a limited range of biological processes have been subjected to imaging because of the lack of a design strategy
Choi, Eun Joung +4 more
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1,3-Dipolar cycloadditions of azomethine imines
Azomethine imines react with alkenes and alkynes to give pyrazolines, pyrazolidines, pyrazolopyridines, indazoloisoquinolines, pyrazolo[1,5-a]isoquinolines and pyrazolopyrazolones through regio-, stereo- and enantioselective 1,3-dipolar cycloadditions.
Nájera, Carmen +2 more
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A rapid and simple procedure was devised for the synthesis of multifunctionalized cyclic β-amino esters and γ-amino alcohols via the 1,3-dipolar cycloaddition of nitrile oxides to β-aminocyclopentenecarboxylates.
Melinda Nonn +3 more
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1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with diazoalkanes [PDF]
2-Thio-3-chloroacrylamides undergo 1,3-dipolar cycloadditions with diazoalkanes leading to a series of novel pyrazolines and pyrazoles. The mechanistic and synthetic features of the cycloadditions to the 2-thio-3-chloroacrylamides at both the sulfide and
Kissane, Marie +2 more
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Studies on Reactions of Isoprenoids. V. 1,3-Dipolar Cycloaddition Adducts of Myrcene with Benzonitrile Oxide [PDF]
Tadashi Sasaki +2 more
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New Substituted Indolizines by 1,3-Dipolar Cycloaddition VI. 7-(4-Nitrobenzyl)indolizines [PDF]
Emilian Georgescu +4 more
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Theoretical analysis of mechanism, regio- and stereoselectivity of 1, 3-dipolar cycloaddition of cyclic nitrone and substituted alkenes by DFT method. [PDF]
Samir Bouacha
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